| Full name: adducin 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q25.1-q25.2 | ||
| Entrez ID: 120 | HGNC ID: HGNC:245 | Ensembl Gene: ENSG00000148700 | OMIM ID: 601568 |
Expression of ADD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADD3 | 120 | 201034_at | -0.3444 | 0.2419 | |
| GSE20347 | ADD3 | 120 | 201753_s_at | 0.0978 | 0.7000 | |
| GSE23400 | ADD3 | 120 | 201034_at | 0.0499 | 0.7296 | |
| GSE26886 | ADD3 | 120 | 201753_s_at | -0.9616 | 0.0086 | |
| GSE29001 | ADD3 | 120 | 201753_s_at | -0.0076 | 0.9877 | |
| GSE38129 | ADD3 | 120 | 201034_at | -0.3032 | 0.0925 | |
| GSE45670 | ADD3 | 120 | 201034_at | -0.5286 | 0.0524 | |
| GSE53622 | ADD3 | 120 | 58298 | -0.3128 | 0.0005 | |
| GSE53624 | ADD3 | 120 | 58298 | -0.3353 | 0.0023 | |
| GSE63941 | ADD3 | 120 | 201034_at | -1.3745 | 0.0088 | |
| GSE77861 | ADD3 | 120 | 201753_s_at | 0.6590 | 0.0569 | |
| GSE97050 | ADD3 | 120 | A_24_P90097 | -0.0713 | 0.7580 | |
| SRP007169 | ADD3 | 120 | RNAseq | 0.4343 | 0.4988 | |
| SRP008496 | ADD3 | 120 | RNAseq | 0.4929 | 0.2495 | |
| SRP064894 | ADD3 | 120 | RNAseq | -0.3538 | 0.2374 | |
| SRP133303 | ADD3 | 120 | RNAseq | -0.2204 | 0.2170 | |
| SRP159526 | ADD3 | 120 | RNAseq | 0.1656 | 0.7539 | |
| SRP193095 | ADD3 | 120 | RNAseq | -0.1964 | 0.3380 | |
| SRP219564 | ADD3 | 120 | RNAseq | -0.1794 | 0.6970 | |
| TCGA | ADD3 | 120 | RNAseq | -0.2041 | 0.0060 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ADD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADD3 | 120 | 1 | 10 | 19 | |
| GSE20123 | ADD3 | 120 | 1 | 9 | 20 | |
| GSE43470 | ADD3 | 120 | 0 | 7 | 36 | |
| GSE46452 | ADD3 | 120 | 0 | 11 | 48 | |
| GSE47630 | ADD3 | 120 | 2 | 14 | 24 | |
| GSE54993 | ADD3 | 120 | 8 | 0 | 62 | |
| GSE54994 | ADD3 | 120 | 1 | 10 | 42 | |
| GSE60625 | ADD3 | 120 | 0 | 0 | 11 | |
| GSE74703 | ADD3 | 120 | 0 | 5 | 31 | |
| GSE74704 | ADD3 | 120 | 1 | 4 | 15 | |
| TCGA | ADD3 | 120 | 4 | 28 | 64 |
Total number of gains: 18; Total number of losses: 98; Total Number of normals: 372.
Somatic mutations of ADD3:
Generating mutation plots.
Highly correlated genes for ADD3:
Showing top 20/201 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADD3 | UBE2J1 | 0.699573 | 3 | 0 | 3 |
| ADD3 | VAMP1 | 0.694471 | 3 | 0 | 3 |
| ADD3 | STRN | 0.68064 | 3 | 0 | 3 |
| ADD3 | MBOAT1 | 0.679811 | 3 | 0 | 3 |
| ADD3 | GABPB1 | 0.670422 | 3 | 0 | 3 |
| ADD3 | NOA1 | 0.663455 | 3 | 0 | 3 |
| ADD3 | ABCA3 | 0.654402 | 3 | 0 | 3 |
| ADD3 | FBXO8 | 0.653458 | 4 | 0 | 3 |
| ADD3 | WDR92 | 0.652468 | 4 | 0 | 3 |
| ADD3 | PIGN | 0.651975 | 3 | 0 | 3 |
| ADD3 | NAGK | 0.644983 | 3 | 0 | 3 |
| ADD3 | CCDC117 | 0.641588 | 3 | 0 | 3 |
| ADD3 | FAM122A | 0.635851 | 3 | 0 | 3 |
| ADD3 | CEP44 | 0.628271 | 3 | 0 | 3 |
| ADD3 | AP3M1 | 0.625728 | 3 | 0 | 3 |
| ADD3 | NINL | 0.623406 | 5 | 0 | 5 |
| ADD3 | RNF111 | 0.622557 | 3 | 0 | 3 |
| ADD3 | PDE4B | 0.622047 | 3 | 0 | 3 |
| ADD3 | PIK3IP1 | 0.620552 | 3 | 0 | 3 |
| ADD3 | PRPH2 | 0.614681 | 4 | 0 | 3 |
For details and further investigation, click here
