| Full name: piwi like RNA-mediated gene silencing 1 | Alias Symbol: PIWI|HIWI|CT80.1 | ||
| Type: protein-coding gene | Cytoband: 12q24.33 | ||
| Entrez ID: 9271 | HGNC ID: HGNC:9007 | Ensembl Gene: ENSG00000125207 | OMIM ID: 605571 |
| Drug and gene relationship at DGIdb | |||
Expression of PIWIL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIWIL1 | 9271 | 214868_at | 0.0686 | 0.7841 | |
| GSE20347 | PIWIL1 | 9271 | 214868_at | -0.0306 | 0.6252 | |
| GSE23400 | PIWIL1 | 9271 | 214868_at | 0.0061 | 0.7249 | |
| GSE26886 | PIWIL1 | 9271 | 214868_at | 0.0174 | 0.8701 | |
| GSE29001 | PIWIL1 | 9271 | 214868_at | 0.0740 | 0.5400 | |
| GSE38129 | PIWIL1 | 9271 | 214868_at | -0.0093 | 0.8784 | |
| GSE45670 | PIWIL1 | 9271 | 214868_at | -0.0268 | 0.8690 | |
| GSE53622 | PIWIL1 | 9271 | 39428 | 0.4164 | 0.0101 | |
| GSE53624 | PIWIL1 | 9271 | 39428 | 0.4325 | 0.0043 | |
| GSE63941 | PIWIL1 | 9271 | 214868_at | 0.0367 | 0.8261 | |
| GSE77861 | PIWIL1 | 9271 | 214868_at | -0.0542 | 0.6213 | |
| TCGA | PIWIL1 | 9271 | RNAseq | 2.4321 | 0.0900 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PIWIL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PIWIL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIWIL1 | 9271 | 4 | 4 | 22 | |
| GSE20123 | PIWIL1 | 9271 | 4 | 4 | 22 | |
| GSE43470 | PIWIL1 | 9271 | 2 | 2 | 39 | |
| GSE46452 | PIWIL1 | 9271 | 8 | 2 | 49 | |
| GSE47630 | PIWIL1 | 9271 | 9 | 3 | 28 | |
| GSE54993 | PIWIL1 | 9271 | 0 | 6 | 64 | |
| GSE54994 | PIWIL1 | 9271 | 4 | 7 | 42 | |
| GSE60625 | PIWIL1 | 9271 | 0 | 0 | 11 | |
| GSE74703 | PIWIL1 | 9271 | 2 | 1 | 33 | |
| GSE74704 | PIWIL1 | 9271 | 2 | 3 | 15 | |
| TCGA | PIWIL1 | 9271 | 21 | 14 | 61 |
Total number of gains: 56; Total number of losses: 46; Total Number of normals: 386.
Somatic mutations of PIWIL1:
Generating mutation plots.
Highly correlated genes for PIWIL1:
Showing all 20 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIWIL1 | CYP46A1 | 0.618097 | 3 | 0 | 3 |
| PIWIL1 | MAST2 | 0.606385 | 3 | 0 | 3 |
| PIWIL1 | MAPK11 | 0.572054 | 3 | 0 | 3 |
| PIWIL1 | UGT2A3 | 0.571969 | 3 | 0 | 3 |
| PIWIL1 | DNM3 | 0.569505 | 4 | 0 | 3 |
| PIWIL1 | ANKRD34C | 0.562287 | 4 | 0 | 3 |
| PIWIL1 | CYP2A13 | 0.54797 | 5 | 0 | 3 |
| PIWIL1 | LGI2 | 0.544711 | 3 | 0 | 3 |
| PIWIL1 | MAPRE3 | 0.538073 | 6 | 0 | 4 |
| PIWIL1 | DENND6B | 0.535314 | 4 | 0 | 3 |
| PIWIL1 | SPEF1 | 0.534406 | 5 | 0 | 3 |
| PIWIL1 | SEMG2 | 0.530922 | 4 | 0 | 3 |
| PIWIL1 | APC2 | 0.519551 | 5 | 0 | 3 |
| PIWIL1 | CNTD2 | 0.5185 | 3 | 0 | 3 |
| PIWIL1 | IQSEC2 | 0.516493 | 5 | 0 | 3 |
| PIWIL1 | MAGEC3 | 0.516406 | 5 | 0 | 4 |
| PIWIL1 | NCAN | 0.506694 | 4 | 0 | 3 |
| PIWIL1 | AVPR2 | 0.505793 | 4 | 0 | 3 |
| PIWIL1 | GNG13 | 0.504534 | 5 | 0 | 3 |
| PIWIL1 | PNLIPRP1 | 0.503029 | 5 | 0 | 3 |
For details and further investigation, click here
