POR

 

Full name: cytochrome p450 oxidoreductase Alias Symbol: CYPOR|FLJ26468
Type: protein-coding gene Cytoband: 7q11.23
Entrez ID: 5447 HGNC ID: HGNC:9208 Ensembl Gene: ENSG00000127948 OMIM ID: 124015
Drug and gene relationship at DGIdb

 

Expression of POR:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 POR 5447 208928_at 0.5866 0.2752
GSE20347 POR 5447 208928_at 0.3532 0.0443
GSE23400 POR 5447 208928_at 0.2134 0.0535
GSE26886 POR 5447 208928_at 0.2015 0.2390
GSE29001 POR 5447 208928_at -0.1604 0.6354
GSE38129 POR 5447 208928_at 0.4847 0.0058
GSE45670 POR 5447 208928_at 0.5217 0.0028
GSE53622 POR 5447 83102 -0.3015 0.0000
GSE53624 POR 5447 83102 -0.0976 0.0558
GSE63941 POR 5447 208928_at 0.7211 0.1910
GSE77861 POR 5447 208928_at 0.3881 0.2137
GSE97050 POR 5447 A_33_P3410895 -0.0284 0.9006
SRP007169 POR 5447 RNAseq -0.6456 0.0698
SRP008496 POR 5447 RNAseq -0.4871 0.0111
SRP064894 POR 5447 RNAseq 0.0364 0.8261
SRP133303 POR 5447 RNAseq 0.1649 0.3612
SRP159526 POR 5447 RNAseq 0.0773 0.7941
SRP193095 POR 5447 RNAseq 0.0974 0.5048
SRP219564 POR 5447 RNAseq 0.0500 0.8357
TCGA POR 5447 RNAseq 0.1711 0.0058

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by POR expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of POR:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 POR 5447 14 1 15
GSE20123 POR 5447 14 1 15
GSE43470 POR 5447 3 2 38
GSE46452 POR 5447 12 0 47
GSE47630 POR 5447 7 2 31
GSE54993 POR 5447 2 7 61
GSE54994 POR 5447 14 3 36
GSE60625 POR 5447 0 0 11
GSE74703 POR 5447 3 1 32
GSE74704 POR 5447 8 1 11
TCGA POR 5447 44 5 47

Total number of gains: 121; Total number of losses: 23; Total Number of normals: 344.  


 

Somatic mutations of POR:

 

Generating mutation plots.

 

Highly correlated genes for POR:

 

Showing top 20/132 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PORABCB90.76513303
PORSALL30.727869303
PORPDCD110.726862303
PORABTB10.722016303
PORPRR150.704937404
PORPLA2G4F0.676924303
PORDRG20.658149303
PORAPBA20.657514303
PORCCDC1420.656423303
PORDUSP90.653746403
PORZNF1820.647769504
PORZNF5240.642556403
PORZDHHC80.63822403
PORMIIP0.637704403
PORNPAS10.637677403
PORBUB1B0.634892504
PORKRIT10.634305303
PORPYGO20.633991404
PORTMEM1020.631376503
PORTMUB10.630645705

For details and further investigation, click here