| Full name: PLAG1 zinc finger | Alias Symbol: ZNF912 | ||
| Type: protein-coding gene | Cytoband: 8q12.1 | ||
| Entrez ID: 5324 | HGNC ID: HGNC:9045 | Ensembl Gene: ENSG00000181690 | OMIM ID: 603026 |
| Drug and gene relationship at DGIdb | |||
Expression of PLAG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLAG1 | 5324 | 205372_at | 1.6694 | 0.2254 | |
| GSE20347 | PLAG1 | 5324 | 205372_at | 1.2152 | 0.0002 | |
| GSE23400 | PLAG1 | 5324 | 205372_at | 0.7271 | 0.0000 | |
| GSE26886 | PLAG1 | 5324 | 205372_at | 0.7751 | 0.1948 | |
| GSE29001 | PLAG1 | 5324 | 205372_at | 1.3994 | 0.0148 | |
| GSE38129 | PLAG1 | 5324 | 205372_at | 0.9741 | 0.0002 | |
| GSE45670 | PLAG1 | 5324 | 205372_at | 1.1327 | 0.0130 | |
| GSE53622 | PLAG1 | 5324 | 54413 | 1.4835 | 0.0000 | |
| GSE53624 | PLAG1 | 5324 | 10931 | 1.6167 | 0.0000 | |
| GSE63941 | PLAG1 | 5324 | 205372_at | -1.0520 | 0.3304 | |
| GSE77861 | PLAG1 | 5324 | 205372_at | 0.5476 | 0.0329 | |
| GSE97050 | PLAG1 | 5324 | A_23_P411723 | 0.4187 | 0.3638 | |
| SRP007169 | PLAG1 | 5324 | RNAseq | 1.1110 | 0.1196 | |
| SRP008496 | PLAG1 | 5324 | RNAseq | 1.3643 | 0.0068 | |
| SRP064894 | PLAG1 | 5324 | RNAseq | 0.2494 | 0.4862 | |
| SRP133303 | PLAG1 | 5324 | RNAseq | 1.3867 | 0.0000 | |
| SRP159526 | PLAG1 | 5324 | RNAseq | 1.7603 | 0.0000 | |
| SRP193095 | PLAG1 | 5324 | RNAseq | 0.8567 | 0.0015 | |
| SRP219564 | PLAG1 | 5324 | RNAseq | 1.4917 | 0.0196 | |
| TCGA | PLAG1 | 5324 | RNAseq | 0.1717 | 0.4432 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by PLAG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLAG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLAG1 | 5324 | 14 | 1 | 15 | |
| GSE20123 | PLAG1 | 5324 | 14 | 1 | 15 | |
| GSE43470 | PLAG1 | 5324 | 13 | 3 | 27 | |
| GSE46452 | PLAG1 | 5324 | 20 | 3 | 36 | |
| GSE47630 | PLAG1 | 5324 | 23 | 1 | 16 | |
| GSE54993 | PLAG1 | 5324 | 1 | 17 | 52 | |
| GSE54994 | PLAG1 | 5324 | 29 | 0 | 24 | |
| GSE60625 | PLAG1 | 5324 | 0 | 4 | 7 | |
| GSE74703 | PLAG1 | 5324 | 12 | 2 | 22 | |
| GSE74704 | PLAG1 | 5324 | 10 | 0 | 10 | |
| TCGA | PLAG1 | 5324 | 43 | 8 | 45 |
Total number of gains: 179; Total number of losses: 40; Total Number of normals: 269.
Somatic mutations of PLAG1:
Generating mutation plots.
Highly correlated genes for PLAG1:
Showing top 20/569 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLAG1 | SPIC | 0.758486 | 3 | 0 | 3 |
| PLAG1 | NAF1 | 0.747401 | 3 | 0 | 3 |
| PLAG1 | CALML5 | 0.725036 | 3 | 0 | 3 |
| PLAG1 | ZNF397 | 0.689221 | 3 | 0 | 3 |
| PLAG1 | SURF6 | 0.686594 | 3 | 0 | 3 |
| PLAG1 | DYRK2 | 0.678643 | 4 | 0 | 4 |
| PLAG1 | WDR81 | 0.675896 | 4 | 0 | 3 |
| PLAG1 | COMMD2 | 0.675302 | 3 | 0 | 3 |
| PLAG1 | TAF1C | 0.671374 | 5 | 0 | 4 |
| PLAG1 | TRADD | 0.664935 | 3 | 0 | 3 |
| PLAG1 | RNF165 | 0.656586 | 3 | 0 | 3 |
| PLAG1 | CHD7 | 0.646443 | 3 | 0 | 3 |
| PLAG1 | ITGAE | 0.643672 | 4 | 0 | 3 |
| PLAG1 | ZNF707 | 0.638392 | 3 | 0 | 3 |
| PLAG1 | UTP23 | 0.634855 | 5 | 0 | 4 |
| PLAG1 | SEC61A2 | 0.634278 | 4 | 0 | 3 |
| PLAG1 | FIP1L1 | 0.633099 | 3 | 0 | 3 |
| PLAG1 | TBCC | 0.631863 | 3 | 0 | 3 |
| PLAG1 | DTNBP1 | 0.63135 | 4 | 0 | 3 |
| PLAG1 | RDH10 | 0.630407 | 4 | 0 | 3 |
For details and further investigation, click here
