| Full name: phospholipase B domain containing 1 | Alias Symbol: FLJ22662 | ||
| Type: protein-coding gene | Cytoband: 12p13.1 | ||
| Entrez ID: 79887 | HGNC ID: HGNC:26215 | Ensembl Gene: ENSG00000121316 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PLBD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLBD1 | 79887 | 218454_at | -0.4075 | 0.7373 | |
| GSE20347 | PLBD1 | 79887 | 218454_at | -1.5150 | 0.0000 | |
| GSE23400 | PLBD1 | 79887 | 218454_at | -1.0919 | 0.0000 | |
| GSE26886 | PLBD1 | 79887 | 218454_at | -3.3309 | 0.0000 | |
| GSE29001 | PLBD1 | 79887 | 218454_at | -0.9903 | 0.0599 | |
| GSE38129 | PLBD1 | 79887 | 218454_at | -1.1031 | 0.0010 | |
| GSE45670 | PLBD1 | 79887 | 218454_at | -0.3599 | 0.3109 | |
| GSE53622 | PLBD1 | 79887 | 62239 | -0.8651 | 0.0000 | |
| GSE53624 | PLBD1 | 79887 | 62239 | -1.3238 | 0.0000 | |
| GSE63941 | PLBD1 | 79887 | 218454_at | 0.8597 | 0.6918 | |
| GSE77861 | PLBD1 | 79887 | 218454_at | -1.6190 | 0.0747 | |
| GSE97050 | PLBD1 | 79887 | A_23_P87709 | -0.5287 | 0.4466 | |
| SRP007169 | PLBD1 | 79887 | RNAseq | -1.5257 | 0.0006 | |
| SRP008496 | PLBD1 | 79887 | RNAseq | -1.5404 | 0.0001 | |
| SRP064894 | PLBD1 | 79887 | RNAseq | -1.3911 | 0.0000 | |
| SRP133303 | PLBD1 | 79887 | RNAseq | -0.8728 | 0.0028 | |
| SRP159526 | PLBD1 | 79887 | RNAseq | -1.4286 | 0.0000 | |
| SRP193095 | PLBD1 | 79887 | RNAseq | -1.9445 | 0.0000 | |
| SRP219564 | PLBD1 | 79887 | RNAseq | -1.8883 | 0.0008 | |
| TCGA | PLBD1 | 79887 | RNAseq | 0.1038 | 0.3769 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by PLBD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLBD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLBD1 | 79887 | 6 | 2 | 22 | |
| GSE20123 | PLBD1 | 79887 | 6 | 2 | 22 | |
| GSE43470 | PLBD1 | 79887 | 9 | 4 | 30 | |
| GSE46452 | PLBD1 | 79887 | 10 | 1 | 48 | |
| GSE47630 | PLBD1 | 79887 | 14 | 1 | 25 | |
| GSE54993 | PLBD1 | 79887 | 1 | 9 | 60 | |
| GSE54994 | PLBD1 | 79887 | 10 | 2 | 41 | |
| GSE60625 | PLBD1 | 79887 | 0 | 1 | 10 | |
| GSE74703 | PLBD1 | 79887 | 9 | 3 | 24 | |
| GSE74704 | PLBD1 | 79887 | 4 | 1 | 15 | |
| TCGA | PLBD1 | 79887 | 40 | 7 | 49 |
Total number of gains: 109; Total number of losses: 33; Total Number of normals: 346.
Somatic mutations of PLBD1:
Generating mutation plots.
Highly correlated genes for PLBD1:
Showing top 20/1412 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLBD1 | GLTP | 0.766281 | 9 | 0 | 9 |
| PLBD1 | TAB3 | 0.746886 | 6 | 0 | 6 |
| PLBD1 | IREB2 | 0.744395 | 3 | 0 | 3 |
| PLBD1 | ATP13A4 | 0.735037 | 7 | 0 | 7 |
| PLBD1 | MPZL3 | 0.734352 | 7 | 0 | 7 |
| PLBD1 | EPHA1 | 0.732018 | 10 | 0 | 10 |
| PLBD1 | ERI2 | 0.729775 | 3 | 0 | 3 |
| PLBD1 | TIAM1 | 0.729714 | 11 | 0 | 11 |
| PLBD1 | TTC9 | 0.728239 | 11 | 0 | 11 |
| PLBD1 | SCEL | 0.724339 | 10 | 0 | 9 |
| PLBD1 | RASSF5 | 0.722937 | 7 | 0 | 7 |
| PLBD1 | RAB11A | 0.719095 | 11 | 0 | 10 |
| PLBD1 | PPL | 0.717703 | 11 | 0 | 11 |
| PLBD1 | ARHGAP27 | 0.717416 | 7 | 0 | 7 |
| PLBD1 | NUAK2 | 0.716692 | 3 | 0 | 3 |
| PLBD1 | ULK3 | 0.715508 | 7 | 0 | 7 |
| PLBD1 | ZDHHC13 | 0.713359 | 11 | 0 | 10 |
| PLBD1 | USP6NL | 0.712707 | 11 | 0 | 11 |
| PLBD1 | SASH1 | 0.712532 | 11 | 0 | 11 |
| PLBD1 | SLURP1 | 0.711335 | 10 | 0 | 10 |
For details and further investigation, click here
