| Full name: mercaptopyruvate sulfurtransferase | Alias Symbol: MST|TST2|TUM1 | ||
| Type: protein-coding gene | Cytoband: 22q12.3 | ||
| Entrez ID: 4357 | HGNC ID: HGNC:7223 | Ensembl Gene: ENSG00000128309 | OMIM ID: 602496 |
| Drug and gene relationship at DGIdb | |||
Expression of MPST:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPST | 4357 | 203524_s_at | -0.3660 | 0.2012 | |
| GSE20347 | MPST | 4357 | 203524_s_at | -0.6089 | 0.0000 | |
| GSE23400 | MPST | 4357 | 203524_s_at | -0.4192 | 0.0000 | |
| GSE26886 | MPST | 4357 | 203524_s_at | 0.1680 | 0.3257 | |
| GSE29001 | MPST | 4357 | 203524_s_at | -0.6382 | 0.0073 | |
| GSE38129 | MPST | 4357 | 203524_s_at | -0.3931 | 0.0020 | |
| GSE45670 | MPST | 4357 | 203524_s_at | -0.1970 | 0.1930 | |
| GSE53622 | MPST | 4357 | 81178 | -0.9161 | 0.0000 | |
| GSE53624 | MPST | 4357 | 81178 | -0.9486 | 0.0000 | |
| GSE63941 | MPST | 4357 | 203524_s_at | 0.5445 | 0.1380 | |
| GSE77861 | MPST | 4357 | 203524_s_at | -0.1489 | 0.4815 | |
| GSE97050 | MPST | 4357 | A_23_P132285 | -0.2424 | 0.3138 | |
| SRP007169 | MPST | 4357 | RNAseq | -1.8982 | 0.0000 | |
| SRP008496 | MPST | 4357 | RNAseq | -2.1769 | 0.0000 | |
| SRP064894 | MPST | 4357 | RNAseq | -0.3317 | 0.4152 | |
| SRP133303 | MPST | 4357 | RNAseq | -1.0203 | 0.0000 | |
| SRP159526 | MPST | 4357 | RNAseq | -0.6588 | 0.0116 | |
| SRP193095 | MPST | 4357 | RNAseq | -1.0273 | 0.0000 | |
| SRP219564 | MPST | 4357 | RNAseq | -0.3414 | 0.4306 | |
| TCGA | MPST | 4357 | RNAseq | -0.1313 | 0.0430 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by MPST expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPST:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPST | 4357 | 6 | 6 | 18 | |
| GSE20123 | MPST | 4357 | 6 | 5 | 19 | |
| GSE43470 | MPST | 4357 | 4 | 6 | 33 | |
| GSE46452 | MPST | 4357 | 31 | 1 | 27 | |
| GSE47630 | MPST | 4357 | 8 | 5 | 27 | |
| GSE54993 | MPST | 4357 | 3 | 6 | 61 | |
| GSE54994 | MPST | 4357 | 10 | 8 | 35 | |
| GSE60625 | MPST | 4357 | 5 | 0 | 6 | |
| GSE74703 | MPST | 4357 | 4 | 4 | 28 | |
| GSE74704 | MPST | 4357 | 3 | 2 | 15 | |
| TCGA | MPST | 4357 | 27 | 16 | 53 |
Total number of gains: 107; Total number of losses: 59; Total Number of normals: 322.
Somatic mutations of MPST:
Generating mutation plots.
Highly correlated genes for MPST:
Showing top 20/1035 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPST | TST | 0.783667 | 12 | 0 | 12 |
| MPST | SLC10A5 | 0.756213 | 3 | 0 | 3 |
| MPST | MCEE | 0.732511 | 5 | 0 | 4 |
| MPST | SPINK7 | 0.731748 | 4 | 0 | 4 |
| MPST | C15orf62 | 0.719467 | 5 | 0 | 4 |
| MPST | ZDHHC21 | 0.718298 | 4 | 0 | 3 |
| MPST | SERPINB11 | 0.716465 | 6 | 0 | 6 |
| MPST | TOM1 | 0.706835 | 10 | 0 | 10 |
| MPST | CBR3-AS1 | 0.706298 | 3 | 0 | 3 |
| MPST | RSPH3 | 0.703488 | 3 | 0 | 3 |
| MPST | TCP11L2 | 0.702887 | 5 | 0 | 5 |
| MPST | CA13 | 0.701076 | 3 | 0 | 3 |
| MPST | HECTD1 | 0.700499 | 3 | 0 | 3 |
| MPST | PLLP | 0.694452 | 9 | 0 | 9 |
| MPST | PLEKHM1 | 0.694362 | 10 | 0 | 10 |
| MPST | PMM1 | 0.69263 | 9 | 0 | 8 |
| MPST | LTA4H | 0.691972 | 3 | 0 | 3 |
| MPST | ATP13A4 | 0.691449 | 6 | 0 | 5 |
| MPST | FAM122A | 0.691178 | 4 | 0 | 4 |
| MPST | ATG9B | 0.68975 | 5 | 0 | 5 |
For details and further investigation, click here
