| Full name: plasmalemma vesicle associated protein | Alias Symbol: gp68|PV-1|PV1|FELS | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 83483 | HGNC ID: HGNC:13635 | Ensembl Gene: ENSG00000130300 | OMIM ID: 607647 |
| Drug and gene relationship at DGIdb | |||
Expression of PLVAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLVAP | 83483 | 221529_s_at | 0.3339 | 0.3936 | |
| GSE20347 | PLVAP | 83483 | 221529_s_at | -0.0129 | 0.9459 | |
| GSE23400 | PLVAP | 83483 | 221529_s_at | 0.1505 | 0.0961 | |
| GSE26886 | PLVAP | 83483 | 221529_s_at | 0.0775 | 0.6929 | |
| GSE29001 | PLVAP | 83483 | 221529_s_at | -0.1613 | 0.4650 | |
| GSE38129 | PLVAP | 83483 | 221529_s_at | -0.1890 | 0.4506 | |
| GSE45670 | PLVAP | 83483 | 221529_s_at | 0.0396 | 0.8941 | |
| GSE53622 | PLVAP | 83483 | 91205 | 0.0698 | 0.4119 | |
| GSE53624 | PLVAP | 83483 | 91205 | 0.2136 | 0.0011 | |
| GSE63941 | PLVAP | 83483 | 221529_s_at | 0.2843 | 0.0527 | |
| GSE77861 | PLVAP | 83483 | 221529_s_at | 0.7199 | 0.0278 | |
| GSE97050 | PLVAP | 83483 | A_23_P56328 | 1.1264 | 0.0620 | |
| SRP007169 | PLVAP | 83483 | RNAseq | 0.0352 | 0.9306 | |
| SRP008496 | PLVAP | 83483 | RNAseq | 0.5507 | 0.1438 | |
| SRP064894 | PLVAP | 83483 | RNAseq | 1.2312 | 0.0001 | |
| SRP133303 | PLVAP | 83483 | RNAseq | 0.0292 | 0.8603 | |
| SRP159526 | PLVAP | 83483 | RNAseq | 0.3838 | 0.2033 | |
| SRP193095 | PLVAP | 83483 | RNAseq | 0.6658 | 0.0047 | |
| SRP219564 | PLVAP | 83483 | RNAseq | 0.6345 | 0.2422 | |
| TCGA | PLVAP | 83483 | RNAseq | -0.2858 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PLVAP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLVAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLVAP | 83483 | 4 | 4 | 22 | |
| GSE20123 | PLVAP | 83483 | 3 | 2 | 25 | |
| GSE43470 | PLVAP | 83483 | 2 | 6 | 35 | |
| GSE46452 | PLVAP | 83483 | 47 | 1 | 11 | |
| GSE47630 | PLVAP | 83483 | 4 | 8 | 28 | |
| GSE54993 | PLVAP | 83483 | 15 | 4 | 51 | |
| GSE54994 | PLVAP | 83483 | 6 | 14 | 33 | |
| GSE60625 | PLVAP | 83483 | 9 | 0 | 2 | |
| GSE74703 | PLVAP | 83483 | 2 | 4 | 30 | |
| GSE74704 | PLVAP | 83483 | 0 | 2 | 18 | |
| TCGA | PLVAP | 83483 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of PLVAP:
Generating mutation plots.
Highly correlated genes for PLVAP:
Showing top 20/328 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLVAP | AGRN | 0.725365 | 3 | 0 | 3 |
| PLVAP | SERPINE1 | 0.707803 | 4 | 0 | 4 |
| PLVAP | AK8 | 0.702367 | 3 | 0 | 3 |
| PLVAP | KCNIP2-AS1 | 0.701106 | 3 | 0 | 3 |
| PLVAP | SUPT5H | 0.698967 | 3 | 0 | 3 |
| PLVAP | SHISA2 | 0.698698 | 3 | 0 | 3 |
| PLVAP | ITGA3 | 0.69682 | 3 | 0 | 3 |
| PLVAP | ITIH5 | 0.692246 | 3 | 0 | 3 |
| PLVAP | S1PR4 | 0.685056 | 3 | 0 | 3 |
| PLVAP | MYBL2 | 0.678007 | 3 | 0 | 3 |
| PLVAP | VMP1 | 0.675412 | 3 | 0 | 3 |
| PLVAP | GRAMD1A | 0.671243 | 6 | 0 | 5 |
| PLVAP | MMP10 | 0.666913 | 3 | 0 | 3 |
| PLVAP | TMEM200C | 0.665089 | 3 | 0 | 3 |
| PLVAP | KDR | 0.66263 | 10 | 0 | 9 |
| PLVAP | DERL3 | 0.659556 | 3 | 0 | 3 |
| PLVAP | ANKRD13B | 0.657617 | 4 | 0 | 3 |
| PLVAP | SEMA4F | 0.653428 | 3 | 0 | 3 |
| PLVAP | PLAU | 0.65308 | 3 | 0 | 3 |
| PLVAP | PLEK | 0.652187 | 6 | 0 | 6 |
For details and further investigation, click here
