| Full name: pyridoxamine 5'-phosphate oxidase | Alias Symbol: PDXPO | ||
| Type: protein-coding gene | Cytoband: 17q21.32 | ||
| Entrez ID: 55163 | HGNC ID: HGNC:30260 | Ensembl Gene: ENSG00000108439 | OMIM ID: 603287 |
Expression of PNPO:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PNPO | 55163 | 222653_at | 0.3294 | 0.4080 | |
| GSE20347 | PNPO | 55163 | 218511_s_at | -0.0700 | 0.6555 | |
| GSE23400 | PNPO | 55163 | 218511_s_at | 0.0735 | 0.1066 | |
| GSE26886 | PNPO | 55163 | 218511_s_at | -0.0500 | 0.8760 | |
| GSE29001 | PNPO | 55163 | 218511_s_at | 0.0819 | 0.8174 | |
| GSE38129 | PNPO | 55163 | 218511_s_at | 0.1023 | 0.4007 | |
| GSE45670 | PNPO | 55163 | 218511_s_at | 0.2518 | 0.1068 | |
| GSE63941 | PNPO | 55163 | 218511_s_at | 0.4158 | 0.1745 | |
| GSE77861 | PNPO | 55163 | 218511_s_at | -0.1085 | 0.6785 | |
| GSE97050 | PNPO | 55163 | A_33_P3243175 | 0.2792 | 0.2913 | |
| SRP007169 | PNPO | 55163 | RNAseq | -0.4598 | 0.1901 | |
| SRP008496 | PNPO | 55163 | RNAseq | -0.5291 | 0.0048 | |
| SRP064894 | PNPO | 55163 | RNAseq | 0.5802 | 0.0018 | |
| SRP133303 | PNPO | 55163 | RNAseq | 0.0455 | 0.7906 | |
| SRP159526 | PNPO | 55163 | RNAseq | 0.2520 | 0.2266 | |
| SRP193095 | PNPO | 55163 | RNAseq | -0.1269 | 0.1805 | |
| SRP219564 | PNPO | 55163 | RNAseq | 0.7650 | 0.0776 | |
| TCGA | PNPO | 55163 | RNAseq | 0.0872 | 0.1042 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PNPO expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of PNPO:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PNPO | 55163 | 5 | 2 | 23 | |
| GSE20123 | PNPO | 55163 | 5 | 2 | 23 | |
| GSE43470 | PNPO | 55163 | 1 | 2 | 40 | |
| GSE46452 | PNPO | 55163 | 32 | 0 | 27 | |
| GSE47630 | PNPO | 55163 | 9 | 0 | 31 | |
| GSE54993 | PNPO | 55163 | 2 | 4 | 64 | |
| GSE54994 | PNPO | 55163 | 11 | 5 | 37 | |
| GSE60625 | PNPO | 55163 | 4 | 0 | 7 | |
| GSE74703 | PNPO | 55163 | 1 | 1 | 34 | |
| GSE74704 | PNPO | 55163 | 4 | 1 | 15 | |
| TCGA | PNPO | 55163 | 27 | 6 | 63 |
Total number of gains: 101; Total number of losses: 23; Total Number of normals: 364.
Somatic mutations of PNPO:
Generating mutation plots.
Highly correlated genes for PNPO:
Showing top 20/172 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PNPO | ZDHHC12 | 0.761171 | 3 | 0 | 3 |
| PNPO | FAM83B | 0.731292 | 3 | 0 | 3 |
| PNPO | FAM83A | 0.714417 | 3 | 0 | 3 |
| PNPO | PSAT1 | 0.709128 | 3 | 0 | 3 |
| PNPO | SP140L | 0.7057 | 3 | 0 | 3 |
| PNPO | SHMT2 | 0.703309 | 3 | 0 | 3 |
| PNPO | ARHGEF19 | 0.694208 | 3 | 0 | 3 |
| PNPO | ATXN7L3 | 0.692291 | 4 | 0 | 3 |
| PNPO | CDK5R1 | 0.688123 | 3 | 0 | 3 |
| PNPO | HTATIP2 | 0.683967 | 4 | 0 | 4 |
| PNPO | HM13 | 0.676778 | 4 | 0 | 3 |
| PNPO | CASP4 | 0.670252 | 3 | 0 | 3 |
| PNPO | PPP1CA | 0.667194 | 4 | 0 | 3 |
| PNPO | TTC39C | 0.658746 | 3 | 0 | 3 |
| PNPO | IFNGR2 | 0.658625 | 3 | 0 | 3 |
| PNPO | ASL | 0.656003 | 4 | 0 | 3 |
| PNPO | WNT10A | 0.648107 | 3 | 0 | 3 |
| PNPO | RPN1 | 0.640733 | 4 | 0 | 3 |
| PNPO | SH3BGRL3 | 0.639277 | 3 | 0 | 3 |
| PNPO | FAM83H | 0.638162 | 4 | 0 | 3 |
For details and further investigation, click here
