| Full name: epithelial membrane protein 2 | Alias Symbol: XMP | ||
| Type: protein-coding gene | Cytoband: 16p13.13 | ||
| Entrez ID: 2013 | HGNC ID: HGNC:3334 | Ensembl Gene: ENSG00000213853 | OMIM ID: 602334 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of EMP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EMP2 | 2013 | 204975_at | -0.2911 | 0.5217 | |
| GSE20347 | EMP2 | 2013 | 204975_at | -0.8392 | 0.0002 | |
| GSE23400 | EMP2 | 2013 | 204975_at | -0.4599 | 0.0001 | |
| GSE26886 | EMP2 | 2013 | 225078_at | -2.0176 | 0.0000 | |
| GSE29001 | EMP2 | 2013 | 204975_at | -0.7479 | 0.2167 | |
| GSE38129 | EMP2 | 2013 | 204975_at | -0.4956 | 0.0432 | |
| GSE45670 | EMP2 | 2013 | 204975_at | -0.2065 | 0.3373 | |
| GSE53622 | EMP2 | 2013 | 137064 | -0.7159 | 0.0000 | |
| GSE53624 | EMP2 | 2013 | 137064 | -0.5192 | 0.0000 | |
| GSE63941 | EMP2 | 2013 | 225079_at | 1.4702 | 0.1032 | |
| GSE77861 | EMP2 | 2013 | 204975_at | -0.3423 | 0.2945 | |
| GSE97050 | EMP2 | 2013 | A_23_P106682 | -0.3179 | 0.3325 | |
| SRP007169 | EMP2 | 2013 | RNAseq | -1.6978 | 0.0000 | |
| SRP008496 | EMP2 | 2013 | RNAseq | -1.3452 | 0.0000 | |
| SRP064894 | EMP2 | 2013 | RNAseq | -0.8836 | 0.0000 | |
| SRP133303 | EMP2 | 2013 | RNAseq | -0.4675 | 0.0573 | |
| SRP159526 | EMP2 | 2013 | RNAseq | -0.9861 | 0.0000 | |
| SRP193095 | EMP2 | 2013 | RNAseq | -0.6194 | 0.0052 | |
| SRP219564 | EMP2 | 2013 | RNAseq | -0.7456 | 0.0564 | |
| TCGA | EMP2 | 2013 | RNAseq | 0.1615 | 0.0416 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by EMP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EMP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EMP2 | 2013 | 5 | 3 | 22 | |
| GSE20123 | EMP2 | 2013 | 5 | 2 | 23 | |
| GSE43470 | EMP2 | 2013 | 3 | 3 | 37 | |
| GSE46452 | EMP2 | 2013 | 38 | 1 | 20 | |
| GSE47630 | EMP2 | 2013 | 14 | 6 | 20 | |
| GSE54993 | EMP2 | 2013 | 3 | 5 | 62 | |
| GSE54994 | EMP2 | 2013 | 5 | 9 | 39 | |
| GSE60625 | EMP2 | 2013 | 4 | 0 | 7 | |
| GSE74703 | EMP2 | 2013 | 3 | 2 | 31 | |
| GSE74704 | EMP2 | 2013 | 2 | 1 | 17 | |
| TCGA | EMP2 | 2013 | 19 | 13 | 64 |
Total number of gains: 101; Total number of losses: 45; Total Number of normals: 342.
Somatic mutations of EMP2:
Generating mutation plots.
Highly correlated genes for EMP2:
Showing top 20/1283 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EMP2 | IMPACT | 0.811875 | 3 | 0 | 3 |
| EMP2 | RNF38 | 0.765933 | 3 | 0 | 3 |
| EMP2 | WDFY1 | 0.750228 | 3 | 0 | 3 |
| EMP2 | PNRC2 | 0.748043 | 3 | 0 | 3 |
| EMP2 | ZNF175 | 0.743354 | 3 | 0 | 3 |
| EMP2 | DDI2 | 0.738282 | 3 | 0 | 3 |
| EMP2 | RTN3 | 0.733853 | 3 | 0 | 3 |
| EMP2 | CCNYL1 | 0.731503 | 4 | 0 | 3 |
| EMP2 | PLEKHA7 | 0.720166 | 8 | 0 | 8 |
| EMP2 | ANO8 | 0.716001 | 4 | 0 | 4 |
| EMP2 | MACC1 | 0.714812 | 5 | 0 | 5 |
| EMP2 | SIAE | 0.710275 | 7 | 0 | 6 |
| EMP2 | TMEM54 | 0.708981 | 4 | 0 | 4 |
| EMP2 | ZCCHC9 | 0.707568 | 3 | 0 | 3 |
| EMP2 | CRBN | 0.705287 | 3 | 0 | 3 |
| EMP2 | GBP6 | 0.704586 | 3 | 0 | 3 |
| EMP2 | EBPL | 0.699466 | 6 | 0 | 5 |
| EMP2 | TRIM6 | 0.696056 | 5 | 0 | 5 |
| EMP2 | ACTR3 | 0.696001 | 3 | 0 | 3 |
| EMP2 | S100A16 | 0.69553 | 6 | 0 | 6 |
For details and further investigation, click here
