| Full name: chromosome 18 open reading frame 21 | Alias Symbol: PNAS-131|PNAS-124|HsT3108 | ||
| Type: protein-coding gene | Cytoband: 18q12.2 | ||
| Entrez ID: 83608 | HGNC ID: HGNC:28802 | Ensembl Gene: ENSG00000141428 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C18orf21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C18orf21 | 83608 | 223526_at | 0.1326 | 0.5601 | |
| GSE26886 | C18orf21 | 83608 | 223526_at | 0.7001 | 0.0059 | |
| GSE45670 | C18orf21 | 83608 | 223526_at | 0.2110 | 0.2276 | |
| GSE53622 | C18orf21 | 83608 | 45249 | 0.2483 | 0.0001 | |
| GSE53624 | C18orf21 | 83608 | 45249 | 0.3147 | 0.0000 | |
| GSE63941 | C18orf21 | 83608 | 223526_at | -0.0768 | 0.9067 | |
| GSE77861 | C18orf21 | 83608 | 223526_at | 0.2403 | 0.5161 | |
| GSE97050 | C18orf21 | 83608 | A_23_P101237 | 0.1669 | 0.5246 | |
| SRP007169 | C18orf21 | 83608 | RNAseq | -0.1383 | 0.7997 | |
| SRP008496 | C18orf21 | 83608 | RNAseq | 0.1817 | 0.6495 | |
| SRP064894 | C18orf21 | 83608 | RNAseq | 0.1610 | 0.4052 | |
| SRP133303 | C18orf21 | 83608 | RNAseq | 0.3977 | 0.0652 | |
| SRP159526 | C18orf21 | 83608 | RNAseq | 0.1711 | 0.5812 | |
| SRP193095 | C18orf21 | 83608 | RNAseq | 0.0091 | 0.9407 | |
| SRP219564 | C18orf21 | 83608 | RNAseq | -0.2891 | 0.3811 | |
| TCGA | C18orf21 | 83608 | RNAseq | 0.0933 | 0.2247 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C18orf21 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C18orf21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C18orf21 | 83608 | 2 | 5 | 23 | |
| GSE20123 | C18orf21 | 83608 | 2 | 5 | 23 | |
| GSE43470 | C18orf21 | 83608 | 0 | 3 | 40 | |
| GSE46452 | C18orf21 | 83608 | 1 | 25 | 33 | |
| GSE47630 | C18orf21 | 83608 | 5 | 20 | 15 | |
| GSE54993 | C18orf21 | 83608 | 8 | 1 | 61 | |
| GSE54994 | C18orf21 | 83608 | 1 | 16 | 36 | |
| GSE60625 | C18orf21 | 83608 | 0 | 4 | 7 | |
| GSE74703 | C18orf21 | 83608 | 0 | 3 | 33 | |
| GSE74704 | C18orf21 | 83608 | 1 | 4 | 15 | |
| TCGA | C18orf21 | 83608 | 16 | 39 | 41 |
Total number of gains: 36; Total number of losses: 125; Total Number of normals: 327.
Somatic mutations of C18orf21:
Generating mutation plots.
Highly correlated genes for C18orf21:
Showing top 20/46 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C18orf21 | PODXL2 | 0.68711 | 3 | 0 | 3 |
| C18orf21 | ZNFX1 | 0.64495 | 3 | 0 | 3 |
| C18orf21 | CELF1 | 0.622719 | 3 | 0 | 3 |
| C18orf21 | IER3IP1 | 0.606579 | 4 | 0 | 3 |
| C18orf21 | PTPRK | 0.597504 | 3 | 0 | 3 |
| C18orf21 | HAUS1 | 0.596906 | 6 | 0 | 5 |
| C18orf21 | ZNF24 | 0.596425 | 6 | 0 | 3 |
| C18orf21 | ELK4 | 0.591931 | 3 | 0 | 3 |
| C18orf21 | C14orf93 | 0.591044 | 3 | 0 | 3 |
| C18orf21 | MRPS17 | 0.580085 | 5 | 0 | 3 |
| C18orf21 | TAP1 | 0.578529 | 4 | 0 | 3 |
| C18orf21 | CEP57 | 0.570092 | 3 | 0 | 3 |
| C18orf21 | C1orf74 | 0.562282 | 4 | 0 | 3 |
| C18orf21 | PIK3C3 | 0.56201 | 6 | 0 | 5 |
| C18orf21 | TAF5 | 0.561814 | 7 | 0 | 4 |
| C18orf21 | CPSF4 | 0.561493 | 4 | 0 | 3 |
| C18orf21 | METTL23 | 0.560832 | 4 | 0 | 3 |
| C18orf21 | TRIM27 | 0.56082 | 5 | 0 | 4 |
| C18orf21 | TTC9C | 0.554869 | 5 | 0 | 3 |
| C18orf21 | RCN1 | 0.553801 | 5 | 0 | 3 |
For details and further investigation, click here
