| Full name: peptidylprolyl isomerase H | Alias Symbol: USA-CYP|CYP-20|SnuCyp-20|CYPH|MGC5016 | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 10465 | HGNC ID: HGNC:14651 | Ensembl Gene: ENSG00000171960 | OMIM ID: 606095 |
| Drug and gene relationship at DGIdb | |||
Expression of PPIH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPIH | 10465 | 204228_at | 0.5212 | 0.1311 | |
| GSE20347 | PPIH | 10465 | 204228_at | 0.4503 | 0.0096 | |
| GSE23400 | PPIH | 10465 | 204228_at | 0.4658 | 0.0000 | |
| GSE26886 | PPIH | 10465 | 204228_at | -0.0789 | 0.7644 | |
| GSE29001 | PPIH | 10465 | 204228_at | 0.2030 | 0.4972 | |
| GSE38129 | PPIH | 10465 | 204228_at | 0.6305 | 0.0000 | |
| GSE45670 | PPIH | 10465 | 204228_at | 0.3168 | 0.0350 | |
| GSE53622 | PPIH | 10465 | 88042 | 0.4811 | 0.0000 | |
| GSE53624 | PPIH | 10465 | 88042 | 0.7523 | 0.0000 | |
| GSE63941 | PPIH | 10465 | 204228_at | 1.2150 | 0.0082 | |
| GSE77861 | PPIH | 10465 | 204228_at | 0.0972 | 0.6527 | |
| GSE97050 | PPIH | 10465 | A_33_P3239122 | 0.1456 | 0.5011 | |
| SRP007169 | PPIH | 10465 | RNAseq | 0.3491 | 0.4329 | |
| SRP008496 | PPIH | 10465 | RNAseq | -0.3864 | 0.2570 | |
| SRP064894 | PPIH | 10465 | RNAseq | 0.4842 | 0.0448 | |
| SRP133303 | PPIH | 10465 | RNAseq | 0.5887 | 0.0077 | |
| SRP193095 | PPIH | 10465 | RNAseq | 0.1959 | 0.1349 | |
| SRP219564 | PPIH | 10465 | RNAseq | 0.6221 | 0.1771 | |
| TCGA | PPIH | 10465 | RNAseq | 0.3509 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PPIH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPIH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPIH | 10465 | 4 | 3 | 23 | |
| GSE20123 | PPIH | 10465 | 3 | 2 | 25 | |
| GSE43470 | PPIH | 10465 | 7 | 2 | 34 | |
| GSE46452 | PPIH | 10465 | 3 | 1 | 55 | |
| GSE47630 | PPIH | 10465 | 9 | 2 | 29 | |
| GSE54993 | PPIH | 10465 | 0 | 2 | 68 | |
| GSE54994 | PPIH | 10465 | 14 | 2 | 37 | |
| GSE60625 | PPIH | 10465 | 0 | 0 | 11 | |
| GSE74703 | PPIH | 10465 | 6 | 1 | 29 | |
| GSE74704 | PPIH | 10465 | 1 | 0 | 19 | |
| TCGA | PPIH | 10465 | 13 | 16 | 67 |
Total number of gains: 60; Total number of losses: 31; Total Number of normals: 397.
Somatic mutations of PPIH:
Generating mutation plots.
Highly correlated genes for PPIH:
Showing top 20/308 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPIH | CC2D1B | 0.742705 | 3 | 0 | 3 |
| PPIH | MIIP | 0.714221 | 5 | 0 | 4 |
| PPIH | LHX1 | 0.711674 | 3 | 0 | 3 |
| PPIH | GPAM | 0.703993 | 3 | 0 | 3 |
| PPIH | ITGA2B | 0.699375 | 3 | 0 | 3 |
| PPIH | RBM28 | 0.689838 | 5 | 0 | 5 |
| PPIH | LRWD1 | 0.689716 | 3 | 0 | 3 |
| PPIH | RAPGEF5 | 0.683669 | 3 | 0 | 3 |
| PPIH | BCL2L12 | 0.677817 | 7 | 0 | 6 |
| PPIH | ARHGAP21 | 0.676608 | 4 | 0 | 3 |
| PPIH | SLC2A6 | 0.676044 | 4 | 0 | 4 |
| PPIH | ZDHHC8 | 0.674827 | 4 | 0 | 4 |
| PPIH | CDCA8 | 0.672429 | 12 | 0 | 10 |
| PPIH | KIF22 | 0.670933 | 9 | 0 | 9 |
| PPIH | KIF2C | 0.670922 | 12 | 0 | 10 |
| PPIH | MTFP1 | 0.670639 | 3 | 0 | 3 |
| PPIH | ALYREF | 0.667966 | 3 | 0 | 3 |
| PPIH | SNORA71A | 0.665826 | 3 | 0 | 3 |
| PPIH | COL27A1 | 0.661975 | 4 | 0 | 3 |
| PPIH | TMEM182 | 0.658079 | 4 | 0 | 3 |
For details and further investigation, click here
