CDCA8

 

Full name: cell division cycle associated 8 Alias Symbol: FLJ12042|MESRGP|BOR|DasraB
Type: protein-coding gene Cytoband: 1p34.3
Entrez ID: 55143 HGNC ID: HGNC:14629 Ensembl Gene: ENSG00000134690 OMIM ID: 609977
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of CDCA8:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CDCA8 55143 221520_s_at 1.1246 0.0393
GSE20347 CDCA8 55143 221520_s_at 0.8764 0.0000
GSE23400 CDCA8 55143 221520_s_at 0.4561 0.0000
GSE26886 CDCA8 55143 221520_s_at 0.0944 0.7718
GSE29001 CDCA8 55143 221520_s_at 0.7230 0.0003
GSE38129 CDCA8 55143 221520_s_at 1.1524 0.0000
GSE45670 CDCA8 55143 221520_s_at 1.1521 0.0000
GSE53622 CDCA8 55143 141534 1.5326 0.0000
GSE53624 CDCA8 55143 141534 1.7188 0.0000
GSE63941 CDCA8 55143 221520_s_at 2.5952 0.0006
GSE77861 CDCA8 55143 221520_s_at 0.3716 0.0279
GSE97050 CDCA8 55143 A_23_P375 1.0824 0.1453
SRP007169 CDCA8 55143 RNAseq 1.5983 0.0005
SRP008496 CDCA8 55143 RNAseq 0.9620 0.0056
SRP064894 CDCA8 55143 RNAseq 1.7227 0.0000
SRP133303 CDCA8 55143 RNAseq 1.6582 0.0000
SRP159526 CDCA8 55143 RNAseq 1.2890 0.0016
SRP193095 CDCA8 55143 RNAseq 0.9446 0.0000
SRP219564 CDCA8 55143 RNAseq 1.9066 0.0097
TCGA CDCA8 55143 RNAseq 0.9502 0.0000

Upregulated datasets: 11; Downregulated datasets: 0.  

 

Survival by CDCA8 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CDCA8:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CDCA8 55143 2 4 24
GSE20123 CDCA8 55143 2 3 25
GSE43470 CDCA8 55143 7 3 33
GSE46452 CDCA8 55143 4 1 54
GSE47630 CDCA8 55143 8 3 29
GSE54993 CDCA8 55143 1 1 68
GSE54994 CDCA8 55143 12 2 39
GSE60625 CDCA8 55143 0 0 11
GSE74703 CDCA8 55143 6 2 28
GSE74704 CDCA8 55143 1 0 19
TCGA CDCA8 55143 12 16 68

Total number of gains: 55; Total number of losses: 35; Total Number of normals: 398.  

 

Somatic mutations of CDCA8:

 

Generating mutation plots.

 

Highly correlated genes for CDCA8:

 

Showing top 20/1218 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CDCA8CDC200.84831413013
CDCA8KIF2C0.84034913013
CDCA8BUB1B0.81569510010
CDCA8UBE2C0.81437512011
CDCA8ESCO20.804824606
CDCA8CEP550.80252111011
CDCA8POC1A0.80049707
CDCA8NUF20.79911707
CDCA8DLGAP50.79514813012
CDCA8C19orf480.795012303
CDCA8ATAD20.79242211011
CDCA8NCAPH0.789819909
CDCA8RAD510.78938712012
CDCA8HJURP0.78857912011
CDCA8CDCA20.787952605
CDCA8UHRF10.787542808
CDCA8UBE2T0.785719706
CDCA8KIF4A0.78380413012
CDCA8ZWINT0.78358712012
CDCA8NEK20.7816612011

For details and further investigation, click here