| Full name: peptidylprolyl isomerase like 6 | Alias Symbol: bA425D10.6|MGC41939|dJ919F19.1|RSPH12 | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 285755 | HGNC ID: HGNC:21557 | Ensembl Gene: ENSG00000185250 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PPIL6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPIL6 | 285755 | 1560910_at | -0.0622 | 0.7856 | |
| GSE26886 | PPIL6 | 285755 | 1560910_at | -0.1727 | 0.1598 | |
| GSE45670 | PPIL6 | 285755 | 1560910_at | -0.2955 | 0.0210 | |
| GSE53622 | PPIL6 | 285755 | 3720 | -0.9064 | 0.0000 | |
| GSE53624 | PPIL6 | 285755 | 24358 | -0.6064 | 0.0000 | |
| GSE63941 | PPIL6 | 285755 | 1553684_at | 0.1910 | 0.5718 | |
| GSE77861 | PPIL6 | 285755 | 1560910_at | -0.0344 | 0.6640 | |
| GSE97050 | PPIL6 | 285755 | A_33_P3211634 | -0.9927 | 0.0665 | |
| SRP007169 | PPIL6 | 285755 | RNAseq | -0.7938 | 0.2008 | |
| SRP064894 | PPIL6 | 285755 | RNAseq | -0.5275 | 0.0362 | |
| SRP133303 | PPIL6 | 285755 | RNAseq | 0.1790 | 0.4294 | |
| SRP159526 | PPIL6 | 285755 | RNAseq | -0.0959 | 0.8349 | |
| SRP193095 | PPIL6 | 285755 | RNAseq | -0.0362 | 0.7793 | |
| SRP219564 | PPIL6 | 285755 | RNAseq | -0.5448 | 0.1760 | |
| TCGA | PPIL6 | 285755 | RNAseq | -0.5802 | 0.0028 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PPIL6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPIL6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPIL6 | 285755 | 3 | 3 | 24 | |
| GSE20123 | PPIL6 | 285755 | 3 | 2 | 25 | |
| GSE43470 | PPIL6 | 285755 | 3 | 1 | 39 | |
| GSE46452 | PPIL6 | 285755 | 2 | 11 | 46 | |
| GSE47630 | PPIL6 | 285755 | 9 | 4 | 27 | |
| GSE54993 | PPIL6 | 285755 | 3 | 2 | 65 | |
| GSE54994 | PPIL6 | 285755 | 8 | 8 | 37 | |
| GSE60625 | PPIL6 | 285755 | 0 | 2 | 9 | |
| GSE74703 | PPIL6 | 285755 | 2 | 1 | 33 | |
| GSE74704 | PPIL6 | 285755 | 1 | 0 | 19 | |
| TCGA | PPIL6 | 285755 | 6 | 24 | 66 |
Total number of gains: 40; Total number of losses: 58; Total Number of normals: 390.
Somatic mutations of PPIL6:
Generating mutation plots.
Highly correlated genes for PPIL6:
Showing top 20/83 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPIL6 | KIF9 | 0.669548 | 3 | 0 | 3 |
| PPIL6 | ANKRD6 | 0.665583 | 3 | 0 | 3 |
| PPIL6 | RPL27A | 0.661828 | 3 | 0 | 3 |
| PPIL6 | IFT57 | 0.651616 | 4 | 0 | 4 |
| PPIL6 | FGF2 | 0.650255 | 3 | 0 | 3 |
| PPIL6 | SAP18 | 0.648856 | 4 | 0 | 4 |
| PPIL6 | IFT74 | 0.635302 | 3 | 0 | 3 |
| PPIL6 | PLEKHG6 | 0.620729 | 3 | 0 | 3 |
| PPIL6 | THAP2 | 0.620652 | 4 | 0 | 4 |
| PPIL6 | ANAPC16 | 0.620552 | 6 | 0 | 4 |
| PPIL6 | DCUN1D4 | 0.612183 | 4 | 0 | 3 |
| PPIL6 | ECHDC2 | 0.611373 | 4 | 0 | 3 |
| PPIL6 | FAM104B | 0.609124 | 4 | 0 | 3 |
| PPIL6 | MBD5 | 0.601435 | 3 | 0 | 3 |
| PPIL6 | GPRASP2 | 0.59576 | 3 | 0 | 3 |
| PPIL6 | SH3BGR | 0.590976 | 3 | 0 | 3 |
| PPIL6 | AK9 | 0.578411 | 3 | 0 | 3 |
| PPIL6 | SRI | 0.575417 | 4 | 0 | 3 |
| PPIL6 | ABCA3 | 0.574224 | 4 | 0 | 4 |
| PPIL6 | PRKAA2 | 0.573609 | 5 | 0 | 3 |
For details and further investigation, click here
