| Full name: solute carrier family 1 member 6 | Alias Symbol: EAAT4 | ||
| Type: protein-coding gene | Cytoband: 19p13.12 | ||
| Entrez ID: 6511 | HGNC ID: HGNC:10944 | Ensembl Gene: ENSG00000105143 | OMIM ID: 600637 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC1A6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC1A6 | 6511 | 206882_at | 0.0342 | 0.9129 | |
| GSE20347 | SLC1A6 | 6511 | 206882_at | 0.0058 | 0.9353 | |
| GSE23400 | SLC1A6 | 6511 | 206882_at | -0.0856 | 0.0154 | |
| GSE26886 | SLC1A6 | 6511 | 206882_at | 0.5046 | 0.0005 | |
| GSE29001 | SLC1A6 | 6511 | 206882_at | 0.0134 | 0.9240 | |
| GSE38129 | SLC1A6 | 6511 | 206882_at | -0.0534 | 0.6039 | |
| GSE45670 | SLC1A6 | 6511 | 206882_at | 0.0971 | 0.6455 | |
| GSE53622 | SLC1A6 | 6511 | 85408 | 0.4271 | 0.0006 | |
| GSE53624 | SLC1A6 | 6511 | 85408 | 0.4189 | 0.0021 | |
| GSE63941 | SLC1A6 | 6511 | 206882_at | 0.4428 | 0.2619 | |
| GSE77861 | SLC1A6 | 6511 | 206882_at | 0.0735 | 0.3923 | |
| SRP133303 | SLC1A6 | 6511 | RNAseq | 0.1119 | 0.4043 | |
| SRP159526 | SLC1A6 | 6511 | RNAseq | 1.7479 | 0.0075 | |
| SRP193095 | SLC1A6 | 6511 | RNAseq | 0.4276 | 0.0187 | |
| TCGA | SLC1A6 | 6511 | RNAseq | 3.1257 | 0.0044 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SLC1A6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC1A6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC1A6 | 6511 | 4 | 2 | 24 | |
| GSE20123 | SLC1A6 | 6511 | 3 | 1 | 26 | |
| GSE43470 | SLC1A6 | 6511 | 2 | 6 | 35 | |
| GSE46452 | SLC1A6 | 6511 | 47 | 1 | 11 | |
| GSE47630 | SLC1A6 | 6511 | 4 | 7 | 29 | |
| GSE54993 | SLC1A6 | 6511 | 15 | 4 | 51 | |
| GSE54994 | SLC1A6 | 6511 | 6 | 13 | 34 | |
| GSE60625 | SLC1A6 | 6511 | 9 | 0 | 2 | |
| GSE74703 | SLC1A6 | 6511 | 2 | 4 | 30 | |
| GSE74704 | SLC1A6 | 6511 | 0 | 1 | 19 | |
| TCGA | SLC1A6 | 6511 | 20 | 10 | 66 |
Total number of gains: 112; Total number of losses: 49; Total Number of normals: 327.
Somatic mutations of SLC1A6:
Generating mutation plots.
Highly correlated genes for SLC1A6:
Showing top 20/371 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC1A6 | GLP1R | 0.714162 | 5 | 0 | 5 |
| SLC1A6 | BMP15 | 0.699351 | 4 | 0 | 4 |
| SLC1A6 | ADARB2 | 0.667098 | 3 | 0 | 3 |
| SLC1A6 | NANOG | 0.659165 | 3 | 0 | 3 |
| SLC1A6 | NPFFR1 | 0.650265 | 7 | 0 | 7 |
| SLC1A6 | PELP1 | 0.647015 | 3 | 0 | 3 |
| SLC1A6 | NPPA | 0.643198 | 3 | 0 | 3 |
| SLC1A6 | PPP1R17 | 0.636981 | 3 | 0 | 3 |
| SLC1A6 | DEFA4 | 0.635312 | 5 | 0 | 5 |
| SLC1A6 | AP4S1 | 0.63115 | 5 | 0 | 5 |
| SLC1A6 | RHO | 0.630508 | 5 | 0 | 4 |
| SLC1A6 | BCAM | 0.628032 | 3 | 0 | 3 |
| SLC1A6 | CSF2 | 0.627098 | 5 | 0 | 3 |
| SLC1A6 | GRIN2B | 0.626212 | 3 | 0 | 3 |
| SLC1A6 | TRH | 0.625167 | 4 | 0 | 4 |
| SLC1A6 | SIX6 | 0.624956 | 4 | 0 | 4 |
| SLC1A6 | ASPDH | 0.623917 | 3 | 0 | 3 |
| SLC1A6 | NR2E3 | 0.623006 | 5 | 0 | 4 |
| SLC1A6 | KCNC2 | 0.62018 | 5 | 0 | 5 |
| SLC1A6 | ZSWIM4 | 0.617977 | 3 | 0 | 3 |
For details and further investigation, click here
