REEP5

 

Full name: receptor accessory protein 5 Alias Symbol: DP1|TB2|D5S346|Yip2e
Type: protein-coding gene Cytoband: 5q22.2
Entrez ID: 7905 HGNC ID: HGNC:30077 Ensembl Gene: ENSG00000129625 OMIM ID: 125265
Drug and gene relationship at DGIdb

 

Expression of REEP5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 REEP5 7905 208872_s_at 0.0409 0.9547
GSE20347 REEP5 7905 208873_s_at -0.6421 0.0000
GSE23400 REEP5 7905 208872_s_at 0.2475 0.0010
GSE26886 REEP5 7905 208873_s_at 0.0625 0.8494
GSE29001 REEP5 7905 208873_s_at -0.0656 0.8775
GSE38129 REEP5 7905 208873_s_at -0.6706 0.0000
GSE45670 REEP5 7905 208872_s_at 0.3712 0.0343
GSE53622 REEP5 7905 71176 -0.6873 0.0000
GSE53624 REEP5 7905 71176 -0.5155 0.0000
GSE63941 REEP5 7905 208872_s_at -0.0006 0.9992
GSE77861 REEP5 7905 208872_s_at -0.0936 0.8208
GSE97050 REEP5 7905 A_23_P350045 -0.5161 0.2191
SRP007169 REEP5 7905 RNAseq -0.3509 0.2975
SRP008496 REEP5 7905 RNAseq -0.1727 0.3079
SRP064894 REEP5 7905 RNAseq 0.1754 0.2828
SRP133303 REEP5 7905 RNAseq 0.1711 0.2179
SRP159526 REEP5 7905 RNAseq -0.3067 0.3769
SRP193095 REEP5 7905 RNAseq -0.4194 0.0001
SRP219564 REEP5 7905 RNAseq 0.0347 0.9010
TCGA REEP5 7905 RNAseq -0.1839 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by REEP5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of REEP5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 REEP5 7905 1 13 16
GSE20123 REEP5 7905 1 13 16
GSE43470 REEP5 7905 3 8 32
GSE46452 REEP5 7905 0 28 31
GSE47630 REEP5 7905 0 21 19
GSE54993 REEP5 7905 9 1 60
GSE54994 REEP5 7905 1 17 35
GSE60625 REEP5 7905 0 0 11
GSE74703 REEP5 7905 2 6 28
GSE74704 REEP5 7905 1 7 12
TCGA REEP5 7905 2 41 53

Total number of gains: 20; Total number of losses: 155; Total Number of normals: 313.  


 

Somatic mutations of REEP5:

 

Generating mutation plots.

 

Highly correlated genes for REEP5:

 

Showing top 20/290 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
REEP5PPP2R5C0.778706404
REEP5PINK10.763426303
REEP5PDHX0.748278303
REEP5ANG0.744659505
REEP5CLEC3B0.741027303
REEP5PPARA0.73373303
REEP5RAB7B0.732827404
REEP5IL6R0.731969303
REEP5SNRNP270.730685303
REEP5PHPT10.725515303
REEP5TRIP110.721057303
REEP5CERS40.70908303
REEP5MOCS20.705495404
REEP5HEMK10.704951303
REEP5BTD0.703084403
REEP5RNASE40.700076504
REEP5CEP1120.693443303
REEP5SMPD10.693158303
REEP5THUMPD10.689804303
REEP5WSB20.686427303

For details and further investigation, click here