| Full name: cell cycle associated protein 1 | Alias Symbol: caprin-1|RNG105 | ||
| Type: protein-coding gene | Cytoband: 11p13 | ||
| Entrez ID: 4076 | HGNC ID: HGNC:6743 | Ensembl Gene: ENSG00000135387 | OMIM ID: 601178 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CAPRIN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CAPRIN1 | 4076 | 225340_s_at | 0.0468 | 0.9471 | |
| GSE20347 | CAPRIN1 | 4076 | 200723_s_at | -0.0101 | 0.9686 | |
| GSE23400 | CAPRIN1 | 4076 | 200723_s_at | 0.5098 | 0.0000 | |
| GSE26886 | CAPRIN1 | 4076 | 225340_s_at | -0.5924 | 0.0162 | |
| GSE29001 | CAPRIN1 | 4076 | 200723_s_at | 0.1457 | 0.7752 | |
| GSE38129 | CAPRIN1 | 4076 | 200723_s_at | 0.2104 | 0.1316 | |
| GSE45670 | CAPRIN1 | 4076 | 225340_s_at | 0.0964 | 0.4999 | |
| GSE53622 | CAPRIN1 | 4076 | 42465 | 0.1485 | 0.0714 | |
| GSE53624 | CAPRIN1 | 4076 | 42465 | 0.0499 | 0.5693 | |
| GSE63941 | CAPRIN1 | 4076 | 200723_s_at | -0.0646 | 0.7974 | |
| GSE77861 | CAPRIN1 | 4076 | 200723_s_at | 0.1781 | 0.6472 | |
| GSE97050 | CAPRIN1 | 4076 | A_33_P3302115 | -0.1515 | 0.4084 | |
| SRP007169 | CAPRIN1 | 4076 | RNAseq | 0.7059 | 0.0263 | |
| SRP008496 | CAPRIN1 | 4076 | RNAseq | 0.7404 | 0.0004 | |
| SRP064894 | CAPRIN1 | 4076 | RNAseq | -0.0043 | 0.9765 | |
| SRP133303 | CAPRIN1 | 4076 | RNAseq | 0.3269 | 0.0302 | |
| SRP159526 | CAPRIN1 | 4076 | RNAseq | -0.1629 | 0.4690 | |
| SRP193095 | CAPRIN1 | 4076 | RNAseq | -0.1549 | 0.0616 | |
| SRP219564 | CAPRIN1 | 4076 | RNAseq | 0.0673 | 0.7111 | |
| TCGA | CAPRIN1 | 4076 | RNAseq | 0.0795 | 0.0542 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CAPRIN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CAPRIN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CAPRIN1 | 4076 | 1 | 6 | 23 | |
| GSE20123 | CAPRIN1 | 4076 | 1 | 5 | 24 | |
| GSE43470 | CAPRIN1 | 4076 | 2 | 4 | 37 | |
| GSE46452 | CAPRIN1 | 4076 | 7 | 5 | 47 | |
| GSE47630 | CAPRIN1 | 4076 | 3 | 10 | 27 | |
| GSE54993 | CAPRIN1 | 4076 | 3 | 2 | 65 | |
| GSE54994 | CAPRIN1 | 4076 | 4 | 9 | 40 | |
| GSE60625 | CAPRIN1 | 4076 | 0 | 0 | 11 | |
| GSE74703 | CAPRIN1 | 4076 | 2 | 2 | 32 | |
| GSE74704 | CAPRIN1 | 4076 | 0 | 3 | 17 | |
| TCGA | CAPRIN1 | 4076 | 13 | 24 | 59 |
Total number of gains: 36; Total number of losses: 70; Total Number of normals: 382.
Somatic mutations of CAPRIN1:
Generating mutation plots.
Highly correlated genes for CAPRIN1:
Showing top 20/417 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CAPRIN1 | APEH | 0.774147 | 3 | 0 | 3 |
| CAPRIN1 | ZNF557 | 0.749941 | 3 | 0 | 3 |
| CAPRIN1 | IMPDH2 | 0.740623 | 3 | 0 | 3 |
| CAPRIN1 | NBAS | 0.732253 | 3 | 0 | 3 |
| CAPRIN1 | IER3IP1 | 0.731725 | 3 | 0 | 3 |
| CAPRIN1 | NCOA4 | 0.730735 | 3 | 0 | 3 |
| CAPRIN1 | ALKBH3 | 0.730018 | 3 | 0 | 3 |
| CAPRIN1 | TMEM50A | 0.722901 | 3 | 0 | 3 |
| CAPRIN1 | SLC28A3 | 0.718476 | 3 | 0 | 3 |
| CAPRIN1 | AQR | 0.717387 | 3 | 0 | 3 |
| CAPRIN1 | FBXL5 | 0.710474 | 3 | 0 | 3 |
| CAPRIN1 | PRDM10 | 0.704613 | 3 | 0 | 3 |
| CAPRIN1 | LAPTM4A | 0.699267 | 4 | 0 | 3 |
| CAPRIN1 | TRIP12 | 0.698207 | 4 | 0 | 4 |
| CAPRIN1 | MTA3 | 0.693523 | 3 | 0 | 3 |
| CAPRIN1 | SRSF8 | 0.692741 | 4 | 0 | 4 |
| CAPRIN1 | CREG1 | 0.691134 | 4 | 0 | 4 |
| CAPRIN1 | PSMC4 | 0.688996 | 4 | 0 | 3 |
| CAPRIN1 | CTBS | 0.688697 | 3 | 0 | 3 |
| CAPRIN1 | FEM1A | 0.68079 | 3 | 0 | 3 |
For details and further investigation, click here
