| Full name: prominin 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q11.1 | ||
| Entrez ID: 150696 | HGNC ID: HGNC:20685 | Ensembl Gene: ENSG00000155066 | OMIM ID: 617160 |
| Drug and gene relationship at DGIdb | |||
Expression of PROM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PROM2 | 150696 | 1552797_s_at | 0.0921 | 0.9479 | |
| GSE26886 | PROM2 | 150696 | 1552797_s_at | -1.8184 | 0.0000 | |
| GSE45670 | PROM2 | 150696 | 1552797_s_at | 0.0852 | 0.7733 | |
| GSE53622 | PROM2 | 150696 | 84692 | -0.9225 | 0.0000 | |
| GSE53624 | PROM2 | 150696 | 84692 | -1.2462 | 0.0000 | |
| GSE63941 | PROM2 | 150696 | 1562378_s_at | 1.1922 | 0.0250 | |
| GSE77861 | PROM2 | 150696 | 1552797_s_at | -0.9690 | 0.2550 | |
| GSE97050 | PROM2 | 150696 | A_33_P3389827 | -0.0454 | 0.8634 | |
| SRP007169 | PROM2 | 150696 | RNAseq | -1.1553 | 0.1059 | |
| SRP008496 | PROM2 | 150696 | RNAseq | -1.4478 | 0.0007 | |
| SRP064894 | PROM2 | 150696 | RNAseq | -0.5691 | 0.1318 | |
| SRP133303 | PROM2 | 150696 | RNAseq | -0.4403 | 0.1798 | |
| SRP159526 | PROM2 | 150696 | RNAseq | -1.3766 | 0.0420 | |
| SRP193095 | PROM2 | 150696 | RNAseq | -0.6175 | 0.0011 | |
| SRP219564 | PROM2 | 150696 | RNAseq | -0.8201 | 0.3924 | |
| TCGA | PROM2 | 150696 | RNAseq | 0.1104 | 0.4663 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by PROM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PROM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PROM2 | 150696 | 7 | 2 | 21 | |
| GSE20123 | PROM2 | 150696 | 7 | 2 | 21 | |
| GSE43470 | PROM2 | 150696 | 3 | 2 | 38 | |
| GSE46452 | PROM2 | 150696 | 2 | 3 | 54 | |
| GSE47630 | PROM2 | 150696 | 7 | 0 | 33 | |
| GSE54993 | PROM2 | 150696 | 0 | 6 | 64 | |
| GSE54994 | PROM2 | 150696 | 11 | 0 | 42 | |
| GSE60625 | PROM2 | 150696 | 0 | 3 | 8 | |
| GSE74703 | PROM2 | 150696 | 3 | 1 | 32 | |
| GSE74704 | PROM2 | 150696 | 4 | 1 | 15 | |
| TCGA | PROM2 | 150696 | 35 | 4 | 57 |
Total number of gains: 79; Total number of losses: 24; Total Number of normals: 385.
Somatic mutations of PROM2:
Generating mutation plots.
Highly correlated genes for PROM2:
Showing top 20/862 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PROM2 | APH1A | 0.736884 | 3 | 0 | 3 |
| PROM2 | KAZN | 0.734356 | 6 | 0 | 6 |
| PROM2 | STARD10 | 0.731025 | 3 | 0 | 3 |
| PROM2 | IVL | 0.707066 | 5 | 0 | 5 |
| PROM2 | HIBCH | 0.705826 | 5 | 0 | 5 |
| PROM2 | UPK3B | 0.703839 | 3 | 0 | 3 |
| PROM2 | EPGN | 0.700685 | 3 | 0 | 3 |
| PROM2 | RHOV | 0.700518 | 7 | 0 | 7 |
| PROM2 | ARF6 | 0.69738 | 5 | 0 | 4 |
| PROM2 | TTC39A | 0.691862 | 5 | 0 | 5 |
| PROM2 | P2RY2 | 0.691075 | 9 | 0 | 8 |
| PROM2 | SLPI | 0.690298 | 6 | 0 | 5 |
| PROM2 | FBXO3 | 0.686921 | 3 | 0 | 3 |
| PROM2 | TTC22 | 0.686692 | 8 | 0 | 7 |
| PROM2 | MAB21L3 | 0.685123 | 5 | 0 | 4 |
| PROM2 | STAP2 | 0.682377 | 4 | 0 | 4 |
| PROM2 | EXOC1 | 0.682205 | 4 | 0 | 4 |
| PROM2 | RREB1 | 0.681333 | 5 | 0 | 5 |
| PROM2 | MIOS | 0.680321 | 6 | 0 | 5 |
| PROM2 | CAPN1 | 0.680245 | 7 | 0 | 7 |
For details and further investigation, click here
