| Full name: apurinic/apyrimidinic endodeoxyribonuclease 2 | Alias Symbol: APEXL2|APE2|XTH2|ZGRF2 | ||
| Type: protein-coding gene | Cytoband: Xp11.21 | ||
| Entrez ID: 27301 | HGNC ID: HGNC:17889 | Ensembl Gene: ENSG00000169188 | OMIM ID: 300773 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of APEX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | APEX2 | 27301 | 204408_at | 0.5615 | 0.2611 | |
| GSE20347 | APEX2 | 27301 | 204408_at | 0.1987 | 0.1335 | |
| GSE23400 | APEX2 | 27301 | 204408_at | 0.2600 | 0.0000 | |
| GSE26886 | APEX2 | 27301 | 204408_at | -0.0305 | 0.8635 | |
| GSE29001 | APEX2 | 27301 | 204408_at | -0.0737 | 0.6994 | |
| GSE38129 | APEX2 | 27301 | 204408_at | 0.3354 | 0.0171 | |
| GSE45670 | APEX2 | 27301 | 204408_at | 0.5088 | 0.0034 | |
| GSE53622 | APEX2 | 27301 | 133378 | 0.1491 | 0.2068 | |
| GSE53624 | APEX2 | 27301 | 133378 | 0.3139 | 0.0000 | |
| GSE63941 | APEX2 | 27301 | 204408_at | 0.9125 | 0.0090 | |
| GSE77861 | APEX2 | 27301 | 204408_at | 0.4027 | 0.0954 | |
| GSE97050 | APEX2 | 27301 | A_23_P256682 | 0.5534 | 0.1682 | |
| SRP007169 | APEX2 | 27301 | RNAseq | 0.2236 | 0.5654 | |
| SRP008496 | APEX2 | 27301 | RNAseq | -0.0622 | 0.8323 | |
| SRP064894 | APEX2 | 27301 | RNAseq | 0.6824 | 0.0006 | |
| SRP133303 | APEX2 | 27301 | RNAseq | 0.4652 | 0.0340 | |
| SRP159526 | APEX2 | 27301 | RNAseq | 0.5217 | 0.0981 | |
| SRP193095 | APEX2 | 27301 | RNAseq | 0.0383 | 0.6726 | |
| SRP219564 | APEX2 | 27301 | RNAseq | 0.6466 | 0.0422 | |
| TCGA | APEX2 | 27301 | RNAseq | 0.2867 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by APEX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of APEX2:
No record found for this gene.
Somatic mutations of APEX2:
Generating mutation plots.
Highly correlated genes for APEX2:
Showing top 20/789 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APEX2 | FAM192A | 0.706245 | 4 | 0 | 4 |
| APEX2 | PPARG | 0.704565 | 3 | 0 | 3 |
| APEX2 | PRR3 | 0.702902 | 4 | 0 | 4 |
| APEX2 | MRI1 | 0.700192 | 3 | 0 | 3 |
| APEX2 | WDR89 | 0.697103 | 3 | 0 | 3 |
| APEX2 | MIEN1 | 0.695759 | 5 | 0 | 4 |
| APEX2 | FLYWCH2 | 0.689861 | 4 | 0 | 3 |
| APEX2 | MMACHC | 0.685234 | 4 | 0 | 3 |
| APEX2 | PPP1R35 | 0.685183 | 4 | 0 | 3 |
| APEX2 | CMIP | 0.684422 | 6 | 0 | 5 |
| APEX2 | RAVER1 | 0.682413 | 5 | 0 | 4 |
| APEX2 | CCDC117 | 0.679366 | 3 | 0 | 3 |
| APEX2 | BCAR1 | 0.678756 | 4 | 0 | 4 |
| APEX2 | NACC1 | 0.677118 | 5 | 0 | 4 |
| APEX2 | CCDC137 | 0.676563 | 4 | 0 | 4 |
| APEX2 | ALG10 | 0.674036 | 4 | 0 | 3 |
| APEX2 | ZHX2 | 0.673405 | 3 | 0 | 3 |
| APEX2 | PLEKHM2 | 0.672188 | 4 | 0 | 3 |
| APEX2 | RAB11B | 0.666735 | 4 | 0 | 3 |
| APEX2 | LSM10 | 0.66243 | 4 | 0 | 3 |
For details and further investigation, click here
