| Full name: immunoglobulin superfamily member 8 | Alias Symbol: CD81P3|EWI2|PGRL|CD316 | ||
| Type: protein-coding gene | Cytoband: 1q23.2 | ||
| Entrez ID: 93185 | HGNC ID: HGNC:17813 | Ensembl Gene: ENSG00000162729 | OMIM ID: 606644 |
| Drug and gene relationship at DGIdb | |||
Expression of IGSF8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IGSF8 | 93185 | 225025_at | 1.1495 | 0.0559 | |
| GSE26886 | IGSF8 | 93185 | 225025_at | 0.5709 | 0.0000 | |
| GSE45670 | IGSF8 | 93185 | 225025_at | 0.2371 | 0.0501 | |
| GSE53622 | IGSF8 | 93185 | 57876 | 0.6640 | 0.0000 | |
| GSE53624 | IGSF8 | 93185 | 57876 | 0.8545 | 0.0000 | |
| GSE63941 | IGSF8 | 93185 | 225025_at | 0.6713 | 0.0688 | |
| GSE77861 | IGSF8 | 93185 | 225025_at | 0.4966 | 0.0521 | |
| GSE97050 | IGSF8 | 93185 | A_33_P3371954 | 0.2793 | 0.4092 | |
| SRP007169 | IGSF8 | 93185 | RNAseq | -0.5158 | 0.1667 | |
| SRP008496 | IGSF8 | 93185 | RNAseq | 0.4416 | 0.1746 | |
| SRP064894 | IGSF8 | 93185 | RNAseq | 0.5163 | 0.0391 | |
| SRP133303 | IGSF8 | 93185 | RNAseq | 0.3845 | 0.1084 | |
| SRP159526 | IGSF8 | 93185 | RNAseq | 0.8778 | 0.0062 | |
| SRP193095 | IGSF8 | 93185 | RNAseq | 0.5667 | 0.0001 | |
| SRP219564 | IGSF8 | 93185 | RNAseq | 1.0743 | 0.0619 | |
| TCGA | IGSF8 | 93185 | RNAseq | 0.1543 | 0.0170 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IGSF8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IGSF8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IGSF8 | 93185 | 10 | 0 | 20 | |
| GSE20123 | IGSF8 | 93185 | 10 | 0 | 20 | |
| GSE43470 | IGSF8 | 93185 | 7 | 2 | 34 | |
| GSE46452 | IGSF8 | 93185 | 2 | 1 | 56 | |
| GSE47630 | IGSF8 | 93185 | 15 | 0 | 25 | |
| GSE54993 | IGSF8 | 93185 | 0 | 5 | 65 | |
| GSE54994 | IGSF8 | 93185 | 16 | 0 | 37 | |
| GSE60625 | IGSF8 | 93185 | 0 | 0 | 11 | |
| GSE74703 | IGSF8 | 93185 | 7 | 2 | 27 | |
| GSE74704 | IGSF8 | 93185 | 4 | 0 | 16 | |
| TCGA | IGSF8 | 93185 | 44 | 3 | 49 |
Total number of gains: 115; Total number of losses: 13; Total Number of normals: 360.
Somatic mutations of IGSF8:
Generating mutation plots.
Highly correlated genes for IGSF8:
Showing top 20/821 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IGSF8 | PRR7 | 0.768103 | 3 | 0 | 3 |
| IGSF8 | RAPGEF4 | 0.747408 | 3 | 0 | 3 |
| IGSF8 | RUNX1-IT1 | 0.721771 | 4 | 0 | 4 |
| IGSF8 | ALKBH6 | 0.719993 | 3 | 0 | 3 |
| IGSF8 | KDM6B | 0.715553 | 4 | 0 | 4 |
| IGSF8 | TP53I13 | 0.694204 | 5 | 0 | 5 |
| IGSF8 | AGRN | 0.692295 | 8 | 0 | 7 |
| IGSF8 | RBM28 | 0.692228 | 3 | 0 | 3 |
| IGSF8 | CCM2 | 0.691422 | 6 | 0 | 6 |
| IGSF8 | ITPK1-AS1 | 0.690637 | 3 | 0 | 3 |
| IGSF8 | MYH10 | 0.68874 | 5 | 0 | 5 |
| IGSF8 | ITGA3 | 0.687505 | 7 | 0 | 7 |
| IGSF8 | FBLIM1 | 0.687503 | 6 | 0 | 6 |
| IGSF8 | SIPA1L3 | 0.686991 | 4 | 0 | 3 |
| IGSF8 | PCGF1 | 0.685119 | 5 | 0 | 5 |
| IGSF8 | CCT3 | 0.685039 | 6 | 0 | 5 |
| IGSF8 | DNMT3B | 0.684025 | 6 | 0 | 6 |
| IGSF8 | ITGB4 | 0.683619 | 7 | 0 | 6 |
| IGSF8 | DNLZ | 0.682923 | 3 | 0 | 3 |
| IGSF8 | GATAD2B | 0.682902 | 4 | 0 | 4 |
For details and further investigation, click here
