| Full name: splicing factor 3b subunit 6 | Alias Symbol: P14|SF3B14a|Ht006|CGI-110|SAP14a | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 51639 | HGNC ID: HGNC:30096 | Ensembl Gene: ENSG00000115128 | OMIM ID: 607835 |
Expression of SF3B6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SF3B6 | 51639 | 223416_at | 0.1144 | 0.6959 | |
| GSE26886 | SF3B6 | 51639 | 223416_at | 0.6901 | 0.0000 | |
| GSE45670 | SF3B6 | 51639 | 223416_at | 0.1797 | 0.2090 | |
| GSE53622 | SF3B6 | 51639 | 15919 | 0.3535 | 0.0000 | |
| GSE53624 | SF3B6 | 51639 | 15919 | 0.5144 | 0.0000 | |
| GSE63941 | SF3B6 | 51639 | 223416_at | 0.8956 | 0.0101 | |
| GSE77861 | SF3B6 | 51639 | 223416_at | 0.1064 | 0.7142 | |
| SRP007169 | SF3B6 | 51639 | RNAseq | -0.4801 | 0.1695 | |
| SRP008496 | SF3B6 | 51639 | RNAseq | -0.1960 | 0.3506 | |
| SRP064894 | SF3B6 | 51639 | RNAseq | 0.0817 | 0.7088 | |
| SRP133303 | SF3B6 | 51639 | RNAseq | 0.2994 | 0.1089 | |
| SRP159526 | SF3B6 | 51639 | RNAseq | 0.0349 | 0.9049 | |
| SRP193095 | SF3B6 | 51639 | RNAseq | -0.3773 | 0.0491 | |
| SRP219564 | SF3B6 | 51639 | RNAseq | -0.2160 | 0.4885 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SF3B6 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SF3B6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SF3B6 | 51639 | 10 | 2 | 18 | |
| GSE20123 | SF3B6 | 51639 | 10 | 2 | 18 | |
| GSE43470 | SF3B6 | 51639 | 2 | 1 | 40 | |
| GSE46452 | SF3B6 | 51639 | 3 | 4 | 52 | |
| GSE47630 | SF3B6 | 51639 | 8 | 0 | 32 | |
| GSE54993 | SF3B6 | 51639 | 0 | 7 | 63 | |
| GSE54994 | SF3B6 | 51639 | 10 | 0 | 43 | |
| GSE60625 | SF3B6 | 51639 | 0 | 3 | 8 | |
| GSE74703 | SF3B6 | 51639 | 2 | 0 | 34 | |
| GSE74704 | SF3B6 | 51639 | 9 | 1 | 10 |
Total number of gains: 54; Total number of losses: 20; Total Number of normals: 318.
Somatic mutations of SF3B6:
Generating mutation plots.
Highly correlated genes for SF3B6:
Showing top 20/459 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SF3B6 | PSMA2 | 0.746373 | 3 | 0 | 3 |
| SF3B6 | RPS27A | 0.692252 | 4 | 0 | 4 |
| SF3B6 | CCT7 | 0.691057 | 4 | 0 | 4 |
| SF3B6 | CPSF3 | 0.688326 | 6 | 0 | 5 |
| SF3B6 | CSE1L | 0.672679 | 4 | 0 | 4 |
| SF3B6 | BRIX1 | 0.66088 | 5 | 0 | 5 |
| SF3B6 | SNRPD2 | 0.655304 | 5 | 0 | 4 |
| SF3B6 | MDH1 | 0.654007 | 4 | 0 | 3 |
| SF3B6 | CAD | 0.652708 | 6 | 0 | 5 |
| SF3B6 | NXT1 | 0.647341 | 3 | 0 | 3 |
| SF3B6 | ADAM17 | 0.646319 | 5 | 0 | 5 |
| SF3B6 | PPM1G | 0.646101 | 5 | 0 | 4 |
| SF3B6 | METTL5 | 0.640782 | 4 | 0 | 4 |
| SF3B6 | DGUOK | 0.638284 | 6 | 0 | 6 |
| SF3B6 | LINC00621 | 0.637736 | 3 | 0 | 3 |
| SF3B6 | SSRP1 | 0.636837 | 4 | 0 | 4 |
| SF3B6 | XPO1 | 0.6357 | 4 | 0 | 4 |
| SF3B6 | LRPPRC | 0.634977 | 7 | 0 | 6 |
| SF3B6 | RNASEH1 | 0.631968 | 5 | 0 | 5 |
| SF3B6 | STC1 | 0.631952 | 3 | 0 | 3 |
For details and further investigation, click here
