TIPIN

 

Full name: TIMELESS interacting protein Alias Symbol: FLJ20516
Type: protein-coding gene Cytoband: 15q22.31
Entrez ID: 54962 HGNC ID: HGNC:30750 Ensembl Gene: ENSG00000075131 OMIM ID: 610716
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of TIPIN:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TIPIN 54962 219258_at 0.4125 0.1842
GSE20347 TIPIN 54962 219258_at 1.3838 0.0000
GSE23400 TIPIN 54962 219258_at 0.5701 0.0000
GSE26886 TIPIN 54962 219258_at 1.1845 0.0001
GSE29001 TIPIN 54962 219258_at 0.7641 0.0682
GSE38129 TIPIN 54962 219258_at 1.3759 0.0000
GSE45670 TIPIN 54962 219258_at 0.9569 0.0006
GSE53622 TIPIN 54962 61335 0.6232 0.0000
GSE53624 TIPIN 54962 61335 0.9837 0.0000
GSE63941 TIPIN 54962 219258_at 1.2993 0.0041
GSE77861 TIPIN 54962 219258_at 1.2362 0.0050
GSE97050 TIPIN 54962 A_23_P99930 -0.2452 0.7788
SRP007169 TIPIN 54962 RNAseq 0.3440 0.5515
SRP008496 TIPIN 54962 RNAseq 0.0910 0.8199
SRP064894 TIPIN 54962 RNAseq 0.7535 0.0003
SRP133303 TIPIN 54962 RNAseq 0.5995 0.0005
SRP159526 TIPIN 54962 RNAseq 0.5430 0.2484
SRP193095 TIPIN 54962 RNAseq 0.5855 0.0000
SRP219564 TIPIN 54962 RNAseq 0.5525 0.1824
TCGA TIPIN 54962 RNAseq 0.5263 0.0000

Upregulated datasets: 5; Downregulated datasets: 0.  

 

Survival by TIPIN expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TIPIN:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TIPIN 54962 7 3 20
GSE20123 TIPIN 54962 7 3 20
GSE43470 TIPIN 54962 4 6 33
GSE46452 TIPIN 54962 3 7 49
GSE47630 TIPIN 54962 8 10 22
GSE54993 TIPIN 54962 5 6 59
GSE54994 TIPIN 54962 6 7 40
GSE60625 TIPIN 54962 4 0 7
GSE74703 TIPIN 54962 4 3 29
GSE74704 TIPIN 54962 3 3 14
TCGA TIPIN 54962 9 16 71

Total number of gains: 60; Total number of losses: 64; Total Number of normals: 364.  

 

Somatic mutations of TIPIN:

 

Generating mutation plots.

 

Highly correlated genes for TIPIN:

 

Showing top 20/1348 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TIPINKNSTRN0.773362707
TIPINPUS70.730555909
TIPINCCNB20.72863813011
TIPINOIP50.72602910010
TIPINSNRPG0.72434211011
TIPINKIF230.72403713012
TIPINCCNB10.72284310010
TIPINTRIP130.72121511011
TIPINSPC250.72032911010
TIPINAURKB0.71407111011
TIPINPSMA40.71191612011
TIPINPTRH20.71155111010
TIPINCDC200.71017111011
TIPINEME10.708888605
TIPINDLGAP50.70804612011
TIPINMCM60.70693213012
TIPINNCAPG0.706610010
TIPINCENPN0.70583613011
TIPINGMNN0.70571213012
TIPINECT20.70525611011

For details and further investigation, click here