| Full name: small ubiquitin like modifier 2 | Alias Symbol: SMT3B | ||
| Type: protein-coding gene | Cytoband: 17q25 | ||
| Entrez ID: 6613 | HGNC ID: HGNC:11125 | Ensembl Gene: ENSG00000188612 | OMIM ID: 603042 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SUMO2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | SUMO2 | 6613 | 10802 | 0.1870 | 0.0000 | |
| GSE53624 | SUMO2 | 6613 | 10802 | 0.2588 | 0.0000 | |
| GSE97050 | SUMO2 | 6613 | A_24_P330691 | 0.1399 | 0.4955 | |
| SRP007169 | SUMO2 | 6613 | RNAseq | -0.7551 | 0.0377 | |
| SRP008496 | SUMO2 | 6613 | RNAseq | -0.5550 | 0.0093 | |
| SRP064894 | SUMO2 | 6613 | RNAseq | 0.1251 | 0.4485 | |
| SRP133303 | SUMO2 | 6613 | RNAseq | 0.4437 | 0.0457 | |
| SRP159526 | SUMO2 | 6613 | RNAseq | 0.2607 | 0.1102 | |
| SRP193095 | SUMO2 | 6613 | RNAseq | -0.2527 | 0.0891 | |
| SRP219564 | SUMO2 | 6613 | RNAseq | 0.0203 | 0.9290 | |
| TCGA | SUMO2 | 6613 | RNAseq | 0.2033 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SUMO2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SUMO2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SUMO2 | 6613 | 6 | 2 | 22 | |
| GSE20123 | SUMO2 | 6613 | 6 | 2 | 22 | |
| GSE43470 | SUMO2 | 6613 | 5 | 3 | 35 | |
| GSE46452 | SUMO2 | 6613 | 33 | 0 | 26 | |
| GSE47630 | SUMO2 | 6613 | 8 | 1 | 31 | |
| GSE54993 | SUMO2 | 6613 | 2 | 5 | 63 | |
| GSE54994 | SUMO2 | 6613 | 10 | 4 | 39 | |
| GSE60625 | SUMO2 | 6613 | 6 | 0 | 5 | |
| GSE74703 | SUMO2 | 6613 | 5 | 1 | 30 | |
| GSE74704 | SUMO2 | 6613 | 4 | 1 | 15 | |
| TCGA | SUMO2 | 6613 | 32 | 10 | 54 |
Total number of gains: 117; Total number of losses: 29; Total Number of normals: 342.
Somatic mutations of SUMO2:
Generating mutation plots.
Highly correlated genes for SUMO2:
Showing top 20/97 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SUMO2 | MRPS7 | 0.737287 | 3 | 0 | 3 |
| SUMO2 | ILF2 | 0.725825 | 3 | 0 | 3 |
| SUMO2 | PSMA4 | 0.711022 | 3 | 0 | 3 |
| SUMO2 | ARL6IP6 | 0.704359 | 3 | 0 | 3 |
| SUMO2 | C1orf43 | 0.7016 | 3 | 0 | 3 |
| SUMO2 | SSRP1 | 0.701419 | 3 | 0 | 3 |
| SUMO2 | PTBP1 | 0.698247 | 3 | 0 | 3 |
| SUMO2 | CACYBP | 0.698125 | 3 | 0 | 3 |
| SUMO2 | TYMS | 0.695199 | 3 | 0 | 3 |
| SUMO2 | C1orf131 | 0.692628 | 3 | 0 | 3 |
| SUMO2 | SUPT16H | 0.692542 | 3 | 0 | 3 |
| SUMO2 | ST13 | 0.69119 | 3 | 0 | 3 |
| SUMO2 | MCM6 | 0.690743 | 3 | 0 | 3 |
| SUMO2 | PAICS | 0.689104 | 3 | 0 | 3 |
| SUMO2 | APEX1 | 0.685507 | 3 | 0 | 3 |
| SUMO2 | SNRPE | 0.684708 | 3 | 0 | 3 |
| SUMO2 | GMNN | 0.680892 | 3 | 0 | 3 |
| SUMO2 | PSMD14 | 0.679967 | 3 | 0 | 3 |
| SUMO2 | SLC44A1 | 0.677921 | 3 | 0 | 3 |
| SUMO2 | ACTL6A | 0.677634 | 3 | 0 | 3 |
For details and further investigation, click here
