| Full name: proteasome 26S subunit, ATPase 5 | Alias Symbol: SUG1|p45/SUG|TBP10|p45|S8|TRIP1|SUG-1 | ||
| Type: protein-coding gene | Cytoband: 17q23.3 | ||
| Entrez ID: 5705 | HGNC ID: HGNC:9552 | Ensembl Gene: ENSG00000087191 | OMIM ID: 601681 |
| Drug and gene relationship at DGIdb | |||
Expression of PSMC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMC5 | 5705 | 209503_s_at | -0.2385 | 0.3538 | |
| GSE20347 | PSMC5 | 5705 | 209503_s_at | -0.1717 | 0.1474 | |
| GSE23400 | PSMC5 | 5705 | 209503_s_at | -0.0239 | 0.6768 | |
| GSE26886 | PSMC5 | 5705 | 209503_s_at | -0.2396 | 0.2550 | |
| GSE29001 | PSMC5 | 5705 | 209503_s_at | -0.0549 | 0.8298 | |
| GSE38129 | PSMC5 | 5705 | 209503_s_at | -0.0629 | 0.5509 | |
| GSE45670 | PSMC5 | 5705 | 209503_s_at | 0.1103 | 0.4318 | |
| GSE53622 | PSMC5 | 5705 | 56440 | -0.0253 | 0.6731 | |
| GSE53624 | PSMC5 | 5705 | 56440 | -0.0491 | 0.4190 | |
| GSE63941 | PSMC5 | 5705 | 209503_s_at | 0.1702 | 0.5515 | |
| GSE77861 | PSMC5 | 5705 | 209503_s_at | 0.4390 | 0.0338 | |
| GSE97050 | PSMC5 | 5705 | A_23_P164035 | 0.1426 | 0.5200 | |
| SRP007169 | PSMC5 | 5705 | RNAseq | 0.2258 | 0.4809 | |
| SRP008496 | PSMC5 | 5705 | RNAseq | 0.1633 | 0.5308 | |
| SRP064894 | PSMC5 | 5705 | RNAseq | 0.4823 | 0.0264 | |
| SRP133303 | PSMC5 | 5705 | RNAseq | 0.0839 | 0.6406 | |
| SRP159526 | PSMC5 | 5705 | RNAseq | 0.1620 | 0.4343 | |
| SRP193095 | PSMC5 | 5705 | RNAseq | -0.2413 | 0.0317 | |
| SRP219564 | PSMC5 | 5705 | RNAseq | 0.2099 | 0.4907 | |
| TCGA | PSMC5 | 5705 | RNAseq | 0.0588 | 0.1930 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSMC5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSMC5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMC5 | 5705 | 3 | 1 | 26 | |
| GSE20123 | PSMC5 | 5705 | 3 | 1 | 26 | |
| GSE43470 | PSMC5 | 5705 | 4 | 0 | 39 | |
| GSE46452 | PSMC5 | 5705 | 31 | 0 | 28 | |
| GSE47630 | PSMC5 | 5705 | 7 | 1 | 32 | |
| GSE54993 | PSMC5 | 5705 | 2 | 5 | 63 | |
| GSE54994 | PSMC5 | 5705 | 9 | 4 | 40 | |
| GSE60625 | PSMC5 | 5705 | 4 | 0 | 7 | |
| GSE74703 | PSMC5 | 5705 | 4 | 0 | 32 | |
| GSE74704 | PSMC5 | 5705 | 3 | 1 | 16 | |
| TCGA | PSMC5 | 5705 | 31 | 9 | 56 |
Total number of gains: 101; Total number of losses: 22; Total Number of normals: 365.
Somatic mutations of PSMC5:
Generating mutation plots.
Highly correlated genes for PSMC5:
Showing top 20/149 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMC5 | PIGS | 0.789032 | 3 | 0 | 3 |
| PSMC5 | RSL1D1 | 0.784339 | 3 | 0 | 3 |
| PSMC5 | UBQLN1 | 0.742302 | 3 | 0 | 3 |
| PSMC5 | GTF3C6 | 0.74227 | 3 | 0 | 3 |
| PSMC5 | LRRC23 | 0.735444 | 3 | 0 | 3 |
| PSMC5 | IWS1 | 0.732517 | 3 | 0 | 3 |
| PSMC5 | SHANK3 | 0.724329 | 3 | 0 | 3 |
| PSMC5 | HEATR6 | 0.711804 | 4 | 0 | 4 |
| PSMC5 | AGGF1 | 0.705962 | 3 | 0 | 3 |
| PSMC5 | NUP88 | 0.688424 | 4 | 0 | 3 |
| PSMC5 | GLOD4 | 0.680787 | 4 | 0 | 3 |
| PSMC5 | CDC40 | 0.673685 | 4 | 0 | 3 |
| PSMC5 | FBXW2 | 0.670786 | 3 | 0 | 3 |
| PSMC5 | EP300 | 0.670561 | 3 | 0 | 3 |
| PSMC5 | RELL2 | 0.6659 | 4 | 0 | 3 |
| PSMC5 | FTSJ3 | 0.657505 | 9 | 0 | 7 |
| PSMC5 | MCFD2 | 0.650541 | 4 | 0 | 3 |
| PSMC5 | PSMD14 | 0.64936 | 4 | 0 | 3 |
| PSMC5 | WIPI1 | 0.646574 | 3 | 0 | 3 |
| PSMC5 | PSMA5 | 0.645524 | 4 | 0 | 3 |
For details and further investigation, click here
