| Full name: NADH:ubiquinone oxidoreductase subunit B1 | Alias Symbol: MNLL|CI-MNLL | ||
| Type: protein-coding gene | Cytoband: 14q31.3 | ||
| Entrez ID: 4707 | HGNC ID: HGNC:7695 | Ensembl Gene: ENSG00000183648 | OMIM ID: 603837 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NDUFB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFB1 | 4707 | 206790_s_at | -0.1458 | 0.7599 | |
| GSE20347 | NDUFB1 | 4707 | 206790_s_at | -0.2346 | 0.0649 | |
| GSE23400 | NDUFB1 | 4707 | 206790_s_at | -0.0419 | 0.6092 | |
| GSE26886 | NDUFB1 | 4707 | 206790_s_at | 0.0945 | 0.4285 | |
| GSE29001 | NDUFB1 | 4707 | 206790_s_at | -0.2590 | 0.2918 | |
| GSE38129 | NDUFB1 | 4707 | 206790_s_at | -0.2554 | 0.0064 | |
| GSE45670 | NDUFB1 | 4707 | 206790_s_at | 0.0099 | 0.9349 | |
| GSE53622 | NDUFB1 | 4707 | 10795 | -0.4437 | 0.0000 | |
| GSE53624 | NDUFB1 | 4707 | 10795 | -0.2467 | 0.0000 | |
| GSE63941 | NDUFB1 | 4707 | 206790_s_at | 0.2724 | 0.3838 | |
| GSE77861 | NDUFB1 | 4707 | 206790_s_at | -0.2861 | 0.1165 | |
| GSE97050 | NDUFB1 | 4707 | A_23_P140423 | -0.4089 | 0.2199 | |
| SRP007169 | NDUFB1 | 4707 | RNAseq | -0.8935 | 0.0199 | |
| SRP008496 | NDUFB1 | 4707 | RNAseq | -0.9419 | 0.0001 | |
| SRP064894 | NDUFB1 | 4707 | RNAseq | 0.1163 | 0.7670 | |
| SRP133303 | NDUFB1 | 4707 | RNAseq | -0.2004 | 0.3032 | |
| SRP159526 | NDUFB1 | 4707 | RNAseq | -0.3601 | 0.2229 | |
| SRP193095 | NDUFB1 | 4707 | RNAseq | -0.8425 | 0.0000 | |
| SRP219564 | NDUFB1 | 4707 | RNAseq | -0.6397 | 0.0164 | |
| TCGA | NDUFB1 | 4707 | RNAseq | -0.0769 | 0.2216 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NDUFB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFB1 | 4707 | 9 | 5 | 16 | |
| GSE20123 | NDUFB1 | 4707 | 9 | 4 | 17 | |
| GSE43470 | NDUFB1 | 4707 | 7 | 3 | 33 | |
| GSE46452 | NDUFB1 | 4707 | 16 | 3 | 40 | |
| GSE47630 | NDUFB1 | 4707 | 11 | 8 | 21 | |
| GSE54993 | NDUFB1 | 4707 | 3 | 8 | 59 | |
| GSE54994 | NDUFB1 | 4707 | 20 | 4 | 29 | |
| GSE60625 | NDUFB1 | 4707 | 0 | 2 | 9 | |
| GSE74703 | NDUFB1 | 4707 | 6 | 3 | 27 | |
| GSE74704 | NDUFB1 | 4707 | 4 | 3 | 13 | |
| TCGA | NDUFB1 | 4707 | 30 | 21 | 45 |
Total number of gains: 115; Total number of losses: 64; Total Number of normals: 309.
Somatic mutations of NDUFB1:
Generating mutation plots.
Highly correlated genes for NDUFB1:
Showing top 20/199 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFB1 | MRPS21 | 0.739522 | 4 | 0 | 3 |
| NDUFB1 | ZNF585A | 0.715346 | 3 | 0 | 3 |
| NDUFB1 | PDHB | 0.694788 | 3 | 0 | 3 |
| NDUFB1 | ABHD14B | 0.689868 | 3 | 0 | 3 |
| NDUFB1 | PPARA | 0.689081 | 3 | 0 | 3 |
| NDUFB1 | CAPN3 | 0.681832 | 3 | 0 | 3 |
| NDUFB1 | PSMG2 | 0.680607 | 3 | 0 | 3 |
| NDUFB1 | PRDM5 | 0.677724 | 3 | 0 | 3 |
| NDUFB1 | EIF4EBP2 | 0.662401 | 4 | 0 | 4 |
| NDUFB1 | CLK4 | 0.661021 | 3 | 0 | 3 |
| NDUFB1 | OXSM | 0.652549 | 3 | 0 | 3 |
| NDUFB1 | SKAP2 | 0.651214 | 3 | 0 | 3 |
| NDUFB1 | NFIA | 0.650786 | 4 | 0 | 4 |
| NDUFB1 | MSRA | 0.648427 | 3 | 0 | 3 |
| NDUFB1 | GSTK1 | 0.645573 | 3 | 0 | 3 |
| NDUFB1 | HOXA4 | 0.64541 | 4 | 0 | 3 |
| NDUFB1 | IK | 0.64455 | 4 | 0 | 4 |
| NDUFB1 | WDR27 | 0.642173 | 3 | 0 | 3 |
| NDUFB1 | ZFP62 | 0.641418 | 3 | 0 | 3 |
| NDUFB1 | APOB | 0.641036 | 3 | 0 | 3 |
For details and further investigation, click here
