| Full name: mitochondrial inner membrane protein MPV17 | Alias Symbol: SYM1 | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 4358 | HGNC ID: HGNC:7224 | Ensembl Gene: ENSG00000115204 | OMIM ID: 137960 |
| Drug and gene relationship at DGIdb | |||
Expression of MPV17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPV17 | 4358 | 203466_at | 0.4893 | 0.1516 | |
| GSE20347 | MPV17 | 4358 | 203466_at | 0.3852 | 0.0428 | |
| GSE23400 | MPV17 | 4358 | 203466_at | 0.4382 | 0.0000 | |
| GSE26886 | MPV17 | 4358 | 203466_at | 0.0411 | 0.8872 | |
| GSE29001 | MPV17 | 4358 | 203466_at | 0.2484 | 0.3987 | |
| GSE38129 | MPV17 | 4358 | 203466_at | 0.3477 | 0.0268 | |
| GSE45670 | MPV17 | 4358 | 203466_at | 0.2220 | 0.2981 | |
| GSE53622 | MPV17 | 4358 | 12358 | 0.7862 | 0.0000 | |
| GSE53624 | MPV17 | 4358 | 34916 | 0.4695 | 0.0000 | |
| GSE63941 | MPV17 | 4358 | 203466_at | -0.0382 | 0.9467 | |
| GSE77861 | MPV17 | 4358 | 203466_at | 0.4065 | 0.2837 | |
| GSE97050 | MPV17 | 4358 | A_33_P3415211 | 0.6750 | 0.1195 | |
| SRP007169 | MPV17 | 4358 | RNAseq | 0.3937 | 0.2989 | |
| SRP008496 | MPV17 | 4358 | RNAseq | 0.4927 | 0.0203 | |
| SRP064894 | MPV17 | 4358 | RNAseq | 0.6157 | 0.0000 | |
| SRP133303 | MPV17 | 4358 | RNAseq | 0.4936 | 0.0000 | |
| SRP159526 | MPV17 | 4358 | RNAseq | 0.1745 | 0.4621 | |
| SRP193095 | MPV17 | 4358 | RNAseq | 0.4048 | 0.0009 | |
| SRP219564 | MPV17 | 4358 | RNAseq | 0.4490 | 0.1663 | |
| TCGA | MPV17 | 4358 | RNAseq | 0.1621 | 0.0024 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MPV17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPV17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPV17 | 4358 | 11 | 2 | 17 | |
| GSE20123 | MPV17 | 4358 | 11 | 2 | 17 | |
| GSE43470 | MPV17 | 4358 | 3 | 1 | 39 | |
| GSE46452 | MPV17 | 4358 | 3 | 4 | 52 | |
| GSE47630 | MPV17 | 4358 | 8 | 0 | 32 | |
| GSE54993 | MPV17 | 4358 | 0 | 6 | 64 | |
| GSE54994 | MPV17 | 4358 | 10 | 0 | 43 | |
| GSE60625 | MPV17 | 4358 | 0 | 3 | 8 | |
| GSE74703 | MPV17 | 4358 | 3 | 0 | 33 | |
| GSE74704 | MPV17 | 4358 | 9 | 1 | 10 | |
| TCGA | MPV17 | 4358 | 37 | 2 | 57 |
Total number of gains: 95; Total number of losses: 21; Total Number of normals: 372.
Somatic mutations of MPV17:
Generating mutation plots.
Highly correlated genes for MPV17:
Showing top 20/1289 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPV17 | PTGFRN | 0.781842 | 3 | 0 | 3 |
| MPV17 | RAB34 | 0.736929 | 3 | 0 | 3 |
| MPV17 | PYCR2 | 0.733276 | 3 | 0 | 3 |
| MPV17 | NGF | 0.728067 | 3 | 0 | 3 |
| MPV17 | AGTRAP | 0.718196 | 3 | 0 | 3 |
| MPV17 | ZNF496 | 0.716954 | 3 | 0 | 3 |
| MPV17 | NFKB2 | 0.715712 | 4 | 0 | 3 |
| MPV17 | PRELID1 | 0.715036 | 3 | 0 | 3 |
| MPV17 | NF1 | 0.708345 | 3 | 0 | 3 |
| MPV17 | PTCD3 | 0.705689 | 6 | 0 | 6 |
| MPV17 | NRM | 0.705522 | 5 | 0 | 5 |
| MPV17 | RNF4 | 0.692406 | 3 | 0 | 3 |
| MPV17 | DGUOK | 0.690097 | 9 | 0 | 8 |
| MPV17 | SLC7A6OS | 0.684039 | 4 | 0 | 4 |
| MPV17 | SLC39A13 | 0.682603 | 4 | 0 | 4 |
| MPV17 | MED1 | 0.681953 | 5 | 0 | 4 |
| MPV17 | SSR3 | 0.674282 | 7 | 0 | 7 |
| MPV17 | IRF2BPL | 0.671936 | 5 | 0 | 4 |
| MPV17 | MRPL45 | 0.671689 | 3 | 0 | 3 |
| MPV17 | BMP2 | 0.665348 | 3 | 0 | 3 |
For details and further investigation, click here
