| Full name: inner membrane mitochondrial protein | Alias Symbol: P87|P89|HMP|MINOS2|Mic60|MICOS60 | ||
| Type: protein-coding gene | Cytoband: 2p11.2 | ||
| Entrez ID: 10989 | HGNC ID: HGNC:6047 | Ensembl Gene: ENSG00000132305 | OMIM ID: 600378 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of IMMT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IMMT | 10989 | 200955_at | 0.0166 | 0.9654 | |
| GSE20347 | IMMT | 10989 | 200955_at | 0.4417 | 0.0033 | |
| GSE23400 | IMMT | 10989 | 200955_at | 0.3536 | 0.0000 | |
| GSE26886 | IMMT | 10989 | 200955_at | 0.5511 | 0.0009 | |
| GSE29001 | IMMT | 10989 | 200955_at | 0.2400 | 0.4625 | |
| GSE38129 | IMMT | 10989 | 200955_at | 0.3876 | 0.0038 | |
| GSE45670 | IMMT | 10989 | 200955_at | 0.1979 | 0.2737 | |
| GSE53622 | IMMT | 10989 | 1575 | 0.5342 | 0.0000 | |
| GSE53624 | IMMT | 10989 | 1575 | 0.5615 | 0.0000 | |
| GSE63941 | IMMT | 10989 | 200955_at | 0.5760 | 0.1251 | |
| GSE77861 | IMMT | 10989 | 200955_at | 0.4414 | 0.0759 | |
| GSE97050 | IMMT | 10989 | A_33_P3314468 | 0.2344 | 0.3772 | |
| SRP007169 | IMMT | 10989 | RNAseq | 0.6144 | 0.0530 | |
| SRP008496 | IMMT | 10989 | RNAseq | 0.6346 | 0.0054 | |
| SRP064894 | IMMT | 10989 | RNAseq | 0.3129 | 0.0001 | |
| SRP133303 | IMMT | 10989 | RNAseq | 0.3451 | 0.0001 | |
| SRP159526 | IMMT | 10989 | RNAseq | 0.5881 | 0.0083 | |
| SRP193095 | IMMT | 10989 | RNAseq | 0.1754 | 0.0250 | |
| SRP219564 | IMMT | 10989 | RNAseq | 0.3109 | 0.4385 | |
| TCGA | IMMT | 10989 | RNAseq | -0.0328 | 0.4397 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IMMT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IMMT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IMMT | 10989 | 9 | 2 | 19 | |
| GSE20123 | IMMT | 10989 | 9 | 2 | 19 | |
| GSE43470 | IMMT | 10989 | 4 | 2 | 37 | |
| GSE46452 | IMMT | 10989 | 2 | 3 | 54 | |
| GSE47630 | IMMT | 10989 | 7 | 0 | 33 | |
| GSE54993 | IMMT | 10989 | 0 | 6 | 64 | |
| GSE54994 | IMMT | 10989 | 10 | 0 | 43 | |
| GSE60625 | IMMT | 10989 | 0 | 3 | 8 | |
| GSE74703 | IMMT | 10989 | 4 | 1 | 31 | |
| GSE74704 | IMMT | 10989 | 7 | 0 | 13 | |
| TCGA | IMMT | 10989 | 35 | 4 | 57 |
Total number of gains: 87; Total number of losses: 23; Total Number of normals: 378.
Somatic mutations of IMMT:
Generating mutation plots.
Highly correlated genes for IMMT:
Showing top 20/1274 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IMMT | DNMBP | 0.725693 | 3 | 0 | 3 |
| IMMT | MTFMT | 0.723641 | 4 | 0 | 4 |
| IMMT | SMCR8 | 0.72295 | 3 | 0 | 3 |
| IMMT | ANKRD40 | 0.709873 | 4 | 0 | 4 |
| IMMT | SMAD3 | 0.708303 | 3 | 0 | 3 |
| IMMT | ABCF1 | 0.708237 | 6 | 0 | 6 |
| IMMT | PTCD3 | 0.703777 | 11 | 0 | 9 |
| IMMT | METTL2A | 0.700365 | 3 | 0 | 3 |
| IMMT | MRPL37 | 0.694923 | 3 | 0 | 3 |
| IMMT | FADS1 | 0.694618 | 3 | 0 | 3 |
| IMMT | NACC1 | 0.693709 | 3 | 0 | 3 |
| IMMT | SH3RF3 | 0.690147 | 3 | 0 | 3 |
| IMMT | DGUOK | 0.68869 | 12 | 0 | 11 |
| IMMT | PIAS2 | 0.685773 | 4 | 0 | 3 |
| IMMT | CHST15 | 0.684233 | 4 | 0 | 4 |
| IMMT | JAG1 | 0.684161 | 3 | 0 | 3 |
| IMMT | KLHL13 | 0.681974 | 6 | 0 | 5 |
| IMMT | RNF138 | 0.681452 | 5 | 0 | 4 |
| IMMT | TRPM4 | 0.681057 | 3 | 0 | 3 |
| IMMT | WDR70 | 0.680204 | 3 | 0 | 3 |
For details and further investigation, click here
