| Full name: quiescin sulfhydryl oxidase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q25.2 | ||
| Entrez ID: 5768 | HGNC ID: HGNC:9756 | Ensembl Gene: ENSG00000116260 | OMIM ID: 603120 |
| Drug and gene relationship at DGIdb | |||
Expression of QSOX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | QSOX1 | 5768 | 201482_at | -0.4504 | 0.1560 | |
| GSE20347 | QSOX1 | 5768 | 201482_at | -0.6086 | 0.0001 | |
| GSE23400 | QSOX1 | 5768 | 201482_at | -0.7623 | 0.0000 | |
| GSE26886 | QSOX1 | 5768 | 201482_at | -2.1955 | 0.0000 | |
| GSE29001 | QSOX1 | 5768 | 201482_at | -1.0280 | 0.0028 | |
| GSE38129 | QSOX1 | 5768 | 201482_at | -0.6285 | 0.0001 | |
| GSE45670 | QSOX1 | 5768 | 201482_at | -0.4689 | 0.0371 | |
| GSE53622 | QSOX1 | 5768 | 4965 | -0.9907 | 0.0000 | |
| GSE53624 | QSOX1 | 5768 | 4965 | -1.0575 | 0.0000 | |
| GSE63941 | QSOX1 | 5768 | 201482_at | -4.7198 | 0.0000 | |
| GSE77861 | QSOX1 | 5768 | 201482_at | -0.5378 | 0.0469 | |
| GSE97050 | QSOX1 | 5768 | A_33_P3225268 | 0.2694 | 0.4693 | |
| SRP007169 | QSOX1 | 5768 | RNAseq | -3.5604 | 0.0000 | |
| SRP008496 | QSOX1 | 5768 | RNAseq | -3.0246 | 0.0000 | |
| SRP064894 | QSOX1 | 5768 | RNAseq | -1.5508 | 0.0000 | |
| SRP133303 | QSOX1 | 5768 | RNAseq | -1.3808 | 0.0000 | |
| SRP159526 | QSOX1 | 5768 | RNAseq | -1.0813 | 0.0011 | |
| SRP193095 | QSOX1 | 5768 | RNAseq | -1.7169 | 0.0000 | |
| SRP219564 | QSOX1 | 5768 | RNAseq | -1.3043 | 0.0007 | |
| TCGA | QSOX1 | 5768 | RNAseq | -0.4163 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by QSOX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of QSOX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | QSOX1 | 5768 | 12 | 0 | 18 | |
| GSE20123 | QSOX1 | 5768 | 12 | 0 | 18 | |
| GSE43470 | QSOX1 | 5768 | 6 | 1 | 36 | |
| GSE46452 | QSOX1 | 5768 | 3 | 1 | 55 | |
| GSE47630 | QSOX1 | 5768 | 14 | 0 | 26 | |
| GSE54993 | QSOX1 | 5768 | 0 | 6 | 64 | |
| GSE54994 | QSOX1 | 5768 | 15 | 0 | 38 | |
| GSE60625 | QSOX1 | 5768 | 0 | 0 | 11 | |
| GSE74703 | QSOX1 | 5768 | 6 | 1 | 29 | |
| GSE74704 | QSOX1 | 5768 | 5 | 0 | 15 | |
| TCGA | QSOX1 | 5768 | 40 | 3 | 53 |
Total number of gains: 113; Total number of losses: 12; Total Number of normals: 363.
Somatic mutations of QSOX1:
Generating mutation plots.
Highly correlated genes for QSOX1:
Showing top 20/1076 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| QSOX1 | SH3GL1 | 0.777099 | 10 | 0 | 10 |
| QSOX1 | ANKRD37 | 0.766828 | 4 | 0 | 4 |
| QSOX1 | VSIG10L | 0.760303 | 6 | 0 | 6 |
| QSOX1 | KRT78 | 0.740121 | 6 | 0 | 6 |
| QSOX1 | ATG9B | 0.733838 | 7 | 0 | 7 |
| QSOX1 | TOM1 | 0.73328 | 12 | 0 | 10 |
| QSOX1 | SCNN1B | 0.730299 | 10 | 0 | 9 |
| QSOX1 | SPINK7 | 0.726905 | 6 | 0 | 6 |
| QSOX1 | PCBP1-AS1 | 0.723456 | 4 | 0 | 3 |
| QSOX1 | CRCT1 | 0.723019 | 10 | 0 | 9 |
| QSOX1 | ANKRD35 | 0.720623 | 7 | 0 | 7 |
| QSOX1 | PAPSS2 | 0.719881 | 3 | 0 | 3 |
| QSOX1 | NIPAL1 | 0.719604 | 3 | 0 | 3 |
| QSOX1 | LTA4H | 0.719535 | 3 | 0 | 3 |
| QSOX1 | AMER2 | 0.71934 | 3 | 0 | 3 |
| QSOX1 | CYSRT1 | 0.719079 | 6 | 0 | 6 |
| QSOX1 | SFTA2 | 0.71834 | 4 | 0 | 4 |
| QSOX1 | SMIM5 | 0.71784 | 6 | 0 | 6 |
| QSOX1 | MLKL | 0.712362 | 3 | 0 | 3 |
| QSOX1 | DEGS2 | 0.710465 | 6 | 0 | 6 |
For details and further investigation, click here
