| Full name: tetratricopeptide repeat domain 23 | Alias Symbol: FLJ12572|HCC-8 | ||
| Type: protein-coding gene | Cytoband: 15q26.3 | ||
| Entrez ID: 64927 | HGNC ID: HGNC:25730 | Ensembl Gene: ENSG00000103852 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TTC23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTC23 | 64927 | 219838_at | -0.0187 | 0.9767 | |
| GSE20347 | TTC23 | 64927 | 219838_at | -0.2201 | 0.0180 | |
| GSE23400 | TTC23 | 64927 | 219838_at | 0.0030 | 0.9560 | |
| GSE26886 | TTC23 | 64927 | 219838_at | -0.3279 | 0.0506 | |
| GSE29001 | TTC23 | 64927 | 219838_at | 0.0362 | 0.8565 | |
| GSE38129 | TTC23 | 64927 | 219838_at | -0.0602 | 0.5490 | |
| GSE45670 | TTC23 | 64927 | 219838_at | 0.0680 | 0.6456 | |
| GSE53622 | TTC23 | 64927 | 62819 | -0.1794 | 0.0276 | |
| GSE53624 | TTC23 | 64927 | 62819 | -0.1548 | 0.0425 | |
| GSE63941 | TTC23 | 64927 | 219838_at | -0.0682 | 0.8755 | |
| GSE77861 | TTC23 | 64927 | 219838_at | -0.2104 | 0.5212 | |
| GSE97050 | TTC23 | 64927 | A_24_P65121 | -0.1098 | 0.7316 | |
| SRP007169 | TTC23 | 64927 | RNAseq | -0.7794 | 0.1399 | |
| SRP008496 | TTC23 | 64927 | RNAseq | -0.4519 | 0.1459 | |
| SRP064894 | TTC23 | 64927 | RNAseq | -0.1383 | 0.2103 | |
| SRP133303 | TTC23 | 64927 | RNAseq | -0.2559 | 0.2548 | |
| SRP159526 | TTC23 | 64927 | RNAseq | -0.2807 | 0.1878 | |
| SRP193095 | TTC23 | 64927 | RNAseq | -0.2014 | 0.0724 | |
| SRP219564 | TTC23 | 64927 | RNAseq | -0.3043 | 0.4079 | |
| TCGA | TTC23 | 64927 | RNAseq | -0.1169 | 0.0413 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TTC23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTC23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTC23 | 64927 | 7 | 1 | 22 | |
| GSE20123 | TTC23 | 64927 | 7 | 1 | 22 | |
| GSE43470 | TTC23 | 64927 | 8 | 3 | 32 | |
| GSE46452 | TTC23 | 64927 | 3 | 7 | 49 | |
| GSE47630 | TTC23 | 64927 | 9 | 10 | 21 | |
| GSE54993 | TTC23 | 64927 | 4 | 7 | 59 | |
| GSE54994 | TTC23 | 64927 | 9 | 7 | 37 | |
| GSE60625 | TTC23 | 64927 | 4 | 0 | 7 | |
| GSE74703 | TTC23 | 64927 | 6 | 3 | 27 | |
| GSE74704 | TTC23 | 64927 | 3 | 2 | 15 | |
| TCGA | TTC23 | 64927 | 19 | 12 | 65 |
Total number of gains: 79; Total number of losses: 53; Total Number of normals: 356.
Somatic mutations of TTC23:
Generating mutation plots.
Highly correlated genes for TTC23:
Showing top 20/264 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTC23 | SRSF8 | 0.776287 | 3 | 0 | 3 |
| TTC23 | SLC9A6 | 0.767931 | 4 | 0 | 4 |
| TTC23 | NUDCD3 | 0.763277 | 3 | 0 | 3 |
| TTC23 | CAPN2 | 0.760136 | 3 | 0 | 3 |
| TTC23 | MBD1 | 0.752932 | 3 | 0 | 3 |
| TTC23 | SNX18 | 0.749434 | 4 | 0 | 4 |
| TTC23 | SCAF8 | 0.741043 | 3 | 0 | 3 |
| TTC23 | APPL2 | 0.740669 | 3 | 0 | 3 |
| TTC23 | STAM | 0.733633 | 3 | 0 | 3 |
| TTC23 | RAB1A | 0.718891 | 3 | 0 | 3 |
| TTC23 | WDR73 | 0.71521 | 3 | 0 | 3 |
| TTC23 | KCMF1 | 0.714236 | 3 | 0 | 3 |
| TTC23 | NIPA2 | 0.705961 | 3 | 0 | 3 |
| TTC23 | DEXI | 0.704269 | 3 | 0 | 3 |
| TTC23 | AP4E1 | 0.70366 | 4 | 0 | 3 |
| TTC23 | CUL2 | 0.703642 | 4 | 0 | 3 |
| TTC23 | GFM2 | 0.701956 | 3 | 0 | 3 |
| TTC23 | NNT | 0.698642 | 3 | 0 | 3 |
| TTC23 | POLE3 | 0.698145 | 3 | 0 | 3 |
| TTC23 | CHCHD4 | 0.697042 | 3 | 0 | 3 |
For details and further investigation, click here
