TMEM119

 

Full name: transmembrane protein 119 Alias Symbol: 
Type: protein-coding gene Cytoband: 12q23.3
Entrez ID: 338773 HGNC ID: HGNC:27884 Ensembl Gene: ENSG00000183160 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TMEM119:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM119 338773 227300_at 0.6675 0.4586
GSE26886 TMEM119 338773 227300_at 0.5456 0.0032
GSE45670 TMEM119 338773 227300_at -0.2292 0.2654
GSE53622 TMEM119 338773 32179 0.6922 0.0000
GSE53624 TMEM119 338773 27441 0.7990 0.0000
GSE63941 TMEM119 338773 227300_at -2.6951 0.0000
GSE77861 TMEM119 338773 227300_at 0.1508 0.3422
GSE97050 TMEM119 338773 A_33_P3395605 0.0879 0.9095
SRP007169 TMEM119 338773 RNAseq 3.3435 0.0001
SRP008496 TMEM119 338773 RNAseq 4.4130 0.0000
SRP064894 TMEM119 338773 RNAseq 2.7258 0.0000
SRP133303 TMEM119 338773 RNAseq 0.9989 0.0004
SRP159526 TMEM119 338773 RNAseq 0.6177 0.0878
SRP193095 TMEM119 338773 RNAseq 0.9366 0.0249
SRP219564 TMEM119 338773 RNAseq 1.5656 0.0660
TCGA TMEM119 338773 RNAseq -0.1752 0.3362

Upregulated datasets: 3; Downregulated datasets: 1.  

 

Survival by TMEM119 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TMEM119:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM119 338773 5 3 22
GSE20123 TMEM119 338773 5 3 22
GSE43470 TMEM119 338773 2 1 40
GSE46452 TMEM119 338773 9 1 49
GSE47630 TMEM119 338773 9 1 30
GSE54993 TMEM119 338773 0 5 65
GSE54994 TMEM119 338773 4 2 47
GSE60625 TMEM119 338773 0 0 11
GSE74703 TMEM119 338773 2 0 34
GSE74704 TMEM119 338773 2 2 16
TCGA TMEM119 338773 21 10 65

Total number of gains: 59; Total number of losses: 28; Total Number of normals: 401.  

 

Somatic mutations of TMEM119:

 

Generating mutation plots.

 

Highly correlated genes for TMEM119:

 

Showing top 20/777 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM119RARRES20.743007808
TMEM119TFEC0.731513505
TMEM119CTSK0.728356908
TMEM119PCOLCE0.723341909
TMEM119TRPV20.713715808
TMEM119FGF70.71217303
TMEM119CCDC1700.705043303
TMEM119PDGFRB0.70487808
TMEM119THY10.702015909
TMEM119PLXND10.697176808
TMEM119PRRX10.694409909
TMEM119HLA-DMA0.69155404
TMEM119OLFML30.690622808
TMEM119GREM10.690115807
TMEM119GAS70.685952303
TMEM119GGT50.685786605
TMEM119CERKL0.685234303
TMEM119FAM219A0.681244303
TMEM119TDRD60.68072403
TMEM119ISLR0.679952909

For details and further investigation, click here