EMILIN1

 

Full name: elastin microfibril interfacer 1 Alias Symbol: DKFZp586M121|gp115
Type: protein-coding gene Cytoband: 2p23.3
Entrez ID: 11117 HGNC ID: HGNC:19880 Ensembl Gene: ENSG00000138080 OMIM ID: 130660
Drug and gene relationship at DGIdb

 

Expression of EMILIN1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 EMILIN1 11117 204163_at -0.2731 0.7649
GSE20347 EMILIN1 11117 204163_at 0.4625 0.0191
GSE23400 EMILIN1 11117 204163_at -0.0709 0.6921
GSE26886 EMILIN1 11117 204163_at 0.7986 0.0020
GSE29001 EMILIN1 11117 204163_at 0.3256 0.3312
GSE38129 EMILIN1 11117 204163_at 0.3286 0.4810
GSE45670 EMILIN1 11117 204163_at -0.6811 0.0111
GSE53622 EMILIN1 11117 104045 0.2036 0.0353
GSE53624 EMILIN1 11117 104045 0.4175 0.0000
GSE63941 EMILIN1 11117 204163_at -3.4467 0.0000
GSE77861 EMILIN1 11117 204163_at 0.1442 0.5483
GSE97050 EMILIN1 11117 A_33_P3333455 0.0402 0.8915
SRP007169 EMILIN1 11117 RNAseq 3.9285 0.0000
SRP008496 EMILIN1 11117 RNAseq 4.3495 0.0000
SRP064894 EMILIN1 11117 RNAseq 1.8523 0.0000
SRP133303 EMILIN1 11117 RNAseq 0.7345 0.0391
SRP159526 EMILIN1 11117 RNAseq 0.6333 0.1878
SRP193095 EMILIN1 11117 RNAseq 1.2632 0.0043
SRP219564 EMILIN1 11117 RNAseq 0.1561 0.8639
TCGA EMILIN1 11117 RNAseq -0.2190 0.0767

Upregulated datasets: 4; Downregulated datasets: 1.  

 

Survival by EMILIN1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of EMILIN1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 EMILIN1 11117 11 2 17
GSE20123 EMILIN1 11117 11 2 17
GSE43470 EMILIN1 11117 3 1 39
GSE46452 EMILIN1 11117 3 4 52
GSE47630 EMILIN1 11117 8 0 32
GSE54993 EMILIN1 11117 0 6 64
GSE54994 EMILIN1 11117 10 0 43
GSE60625 EMILIN1 11117 0 3 8
GSE74703 EMILIN1 11117 3 0 33
GSE74704 EMILIN1 11117 9 1 10
TCGA EMILIN1 11117 37 2 57

Total number of gains: 95; Total number of losses: 21; Total Number of normals: 372.  

 

Somatic mutations of EMILIN1:

 

Generating mutation plots.

 

Highly correlated genes for EMILIN1:

 

Showing top 20/525 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
EMILIN1RARRES20.75942413013
EMILIN1DNM3OS0.758881404
EMILIN1TCEAL70.757956808
EMILIN1RBM430.752136303
EMILIN1SETDB20.750528303
EMILIN1HEPH0.74219711010
EMILIN1SCN9A0.730613303
EMILIN1PMP220.72938811011
EMILIN1DDR20.72329212010
EMILIN1FBN10.71802810010
EMILIN1ISLR0.71776412012
EMILIN1FAT40.715136706
EMILIN1ANK20.708146505
EMILIN1MXRA80.70536611010
EMILIN1PCOLCE0.70456812012
EMILIN1MMP23B0.700927303
EMILIN1PLN0.698533606
EMILIN1DCHS10.6969841008
EMILIN1COL6A10.6969812011
EMILIN1SCARF20.696308505

For details and further investigation, click here