C3AR1

 

Full name: complement C3a receptor 1 Alias Symbol: C3AR|AZ3B
Type: protein-coding gene Cytoband: 12p13.31
Entrez ID: 719 HGNC ID: HGNC:1319 Ensembl Gene: ENSG00000171860 OMIM ID: 605246
Drug and gene relationship at DGIdb

 

C3AR1 involved pathways:

KEGG pathway Description View
hsa05150Staphylococcus aureus infection

 

Expression of C3AR1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C3AR1 719 209906_at 0.4220 0.7049
GSE20347 C3AR1 719 209906_at 0.4829 0.0004
GSE23400 C3AR1 719 209906_at 0.2567 0.0000
GSE26886 C3AR1 719 209906_at 0.2832 0.3182
GSE29001 C3AR1 719 209906_at 0.8749 0.0164
GSE38129 C3AR1 719 209906_at 0.4690 0.0094
GSE45670 C3AR1 719 209906_at -0.1795 0.5999
GSE53622 C3AR1 719 96278 0.5164 0.0000
GSE53624 C3AR1 719 96278 0.7429 0.0000
GSE63941 C3AR1 719 209906_at 0.0511 0.7906
GSE77861 C3AR1 719 209906_at -0.0073 0.9638
GSE97050 C3AR1 719 A_23_P2431 0.3476 0.3313
SRP007169 C3AR1 719 RNAseq 3.1748 0.0002
SRP008496 C3AR1 719 RNAseq 2.6993 0.0000
SRP064894 C3AR1 719 RNAseq 0.9953 0.0052
SRP133303 C3AR1 719 RNAseq 0.8657 0.0019
SRP159526 C3AR1 719 RNAseq 0.7120 0.3196
SRP219564 C3AR1 719 RNAseq 1.2363 0.1278
TCGA C3AR1 719 RNAseq 0.1753 0.2557

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by C3AR1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of C3AR1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C3AR1 719 6 3 21
GSE20123 C3AR1 719 6 3 21
GSE43470 C3AR1 719 7 3 33
GSE46452 C3AR1 719 10 1 48
GSE47630 C3AR1 719 12 2 26
GSE54993 C3AR1 719 1 10 59
GSE54994 C3AR1 719 8 3 42
GSE60625 C3AR1 719 0 1 10
GSE74703 C3AR1 719 7 2 27
GSE74704 C3AR1 719 4 2 14
TCGA C3AR1 719 40 6 50

Total number of gains: 101; Total number of losses: 36; Total Number of normals: 351.  

 

Somatic mutations of C3AR1:

 

Generating mutation plots.

 

Highly correlated genes for C3AR1:

 

Showing top 20/751 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C3AR1FCER1G0.81755410010
C3AR1CD1630.80531311011
C3AR1FCGR3A0.804808303
C3AR1TYROBP0.80391911010
C3AR1CD140.80084611010
C3AR1C1QB0.80072411010
C3AR1TFEC0.79942310010
C3AR1MS4A4A0.79608310010
C3AR1C1QA0.76800512010
C3AR1RASSF40.753931504
C3AR1RAB420.741101303
C3AR1C19orf380.740734303
C3AR1ETS10.738871404
C3AR1CERKL0.738802303
C3AR1MNDA0.73824711011
C3AR1SLC7A70.73608811010
C3AR1BORA0.734549303
C3AR1GPR340.730409605
C3AR1C1QC0.724752705
C3AR1DRAM10.71713810010

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