| Full name: transmembrane protein 131 | Alias Symbol: CC28|YR-23|RW1|KIAA0257|PRO1048 | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 23505 | HGNC ID: HGNC:30366 | Ensembl Gene: ENSG00000075568 | OMIM ID: 615659 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM131:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM131 | 23505 | 212507_at | 0.0790 | 0.8786 | |
| GSE20347 | TMEM131 | 23505 | 212507_at | -0.3095 | 0.0575 | |
| GSE23400 | TMEM131 | 23505 | 212507_at | 0.0803 | 0.2505 | |
| GSE26886 | TMEM131 | 23505 | 212507_at | 0.4612 | 0.1125 | |
| GSE29001 | TMEM131 | 23505 | 212507_at | -0.2814 | 0.3262 | |
| GSE38129 | TMEM131 | 23505 | 212507_at | -0.1223 | 0.3191 | |
| GSE45670 | TMEM131 | 23505 | 212507_at | -0.2139 | 0.0929 | |
| GSE53622 | TMEM131 | 23505 | 32999 | -0.0994 | 0.0603 | |
| GSE53624 | TMEM131 | 23505 | 27297 | -0.1815 | 0.0037 | |
| GSE63941 | TMEM131 | 23505 | 212507_at | -0.5309 | 0.1962 | |
| GSE77861 | TMEM131 | 23505 | 212507_at | -0.1285 | 0.5746 | |
| GSE97050 | TMEM131 | 23505 | A_23_P368558 | 0.1478 | 0.5916 | |
| SRP007169 | TMEM131 | 23505 | RNAseq | -0.0042 | 0.9911 | |
| SRP008496 | TMEM131 | 23505 | RNAseq | 0.2091 | 0.2781 | |
| SRP064894 | TMEM131 | 23505 | RNAseq | -0.2868 | 0.0794 | |
| SRP133303 | TMEM131 | 23505 | RNAseq | 0.1233 | 0.2719 | |
| SRP159526 | TMEM131 | 23505 | RNAseq | 0.6703 | 0.1083 | |
| SRP193095 | TMEM131 | 23505 | RNAseq | -0.3519 | 0.0013 | |
| SRP219564 | TMEM131 | 23505 | RNAseq | -0.3007 | 0.3474 | |
| TCGA | TMEM131 | 23505 | RNAseq | -0.0982 | 0.0174 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM131 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM131:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM131 | 23505 | 6 | 2 | 22 | |
| GSE20123 | TMEM131 | 23505 | 6 | 2 | 22 | |
| GSE43470 | TMEM131 | 23505 | 3 | 3 | 37 | |
| GSE46452 | TMEM131 | 23505 | 2 | 3 | 54 | |
| GSE47630 | TMEM131 | 23505 | 7 | 0 | 33 | |
| GSE54993 | TMEM131 | 23505 | 0 | 6 | 64 | |
| GSE54994 | TMEM131 | 23505 | 11 | 0 | 42 | |
| GSE60625 | TMEM131 | 23505 | 0 | 3 | 8 | |
| GSE74703 | TMEM131 | 23505 | 3 | 2 | 31 | |
| GSE74704 | TMEM131 | 23505 | 4 | 1 | 15 | |
| TCGA | TMEM131 | 23505 | 35 | 3 | 58 |
Total number of gains: 77; Total number of losses: 25; Total Number of normals: 386.
Somatic mutations of TMEM131:
Generating mutation plots.
Highly correlated genes for TMEM131:
Showing top 20/250 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM131 | RBM4 | 0.747548 | 3 | 0 | 3 |
| TMEM131 | SMCR8 | 0.736059 | 3 | 0 | 3 |
| TMEM131 | FGFR1OP | 0.726634 | 3 | 0 | 3 |
| TMEM131 | NSRP1 | 0.725644 | 3 | 0 | 3 |
| TMEM131 | ZNF121 | 0.72557 | 3 | 0 | 3 |
| TMEM131 | ANAPC5 | 0.719455 | 3 | 0 | 3 |
| TMEM131 | ACBD5 | 0.716938 | 3 | 0 | 3 |
| TMEM131 | LAMP1 | 0.698097 | 3 | 0 | 3 |
| TMEM131 | RPUSD4 | 0.695214 | 3 | 0 | 3 |
| TMEM131 | ARID2 | 0.69457 | 4 | 0 | 4 |
| TMEM131 | GUSB | 0.691551 | 3 | 0 | 3 |
| TMEM131 | DOCK7 | 0.691276 | 3 | 0 | 3 |
| TMEM131 | CBFA2T2 | 0.685595 | 3 | 0 | 3 |
| TMEM131 | SLC35B3 | 0.684299 | 3 | 0 | 3 |
| TMEM131 | BACE2 | 0.68363 | 3 | 0 | 3 |
| TMEM131 | TDP2 | 0.680799 | 3 | 0 | 3 |
| TMEM131 | SPEN | 0.674258 | 3 | 0 | 3 |
| TMEM131 | PIP4K2C | 0.672924 | 3 | 0 | 3 |
| TMEM131 | STARD7 | 0.6713 | 3 | 0 | 3 |
| TMEM131 | ARF6 | 0.670639 | 3 | 0 | 3 |
For details and further investigation, click here
