| Full name: MAD2L1 binding protein | Alias Symbol: CMT2|KIAA0110|dJ261G23.1 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 9587 | HGNC ID: HGNC:21059 | Ensembl Gene: ENSG00000124688 | OMIM ID: 618136 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MAD2L1BP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAD2L1BP | 9587 | 203094_at | 0.2455 | 0.4977 | |
| GSE20347 | MAD2L1BP | 9587 | 203094_at | 0.2327 | 0.1519 | |
| GSE23400 | MAD2L1BP | 9587 | 203094_at | 0.2151 | 0.0000 | |
| GSE26886 | MAD2L1BP | 9587 | 203094_at | 0.1332 | 0.3648 | |
| GSE29001 | MAD2L1BP | 9587 | 203094_at | 0.2358 | 0.1816 | |
| GSE38129 | MAD2L1BP | 9587 | 203094_at | 0.3238 | 0.0084 | |
| GSE45670 | MAD2L1BP | 9587 | 203094_at | 0.3545 | 0.0063 | |
| GSE53622 | MAD2L1BP | 9587 | 43825 | 0.3925 | 0.0000 | |
| GSE53624 | MAD2L1BP | 9587 | 43825 | 0.4776 | 0.0000 | |
| GSE63941 | MAD2L1BP | 9587 | 203094_at | 0.4919 | 0.1011 | |
| GSE77861 | MAD2L1BP | 9587 | 203094_at | 0.0631 | 0.8295 | |
| GSE97050 | MAD2L1BP | 9587 | A_24_P43588 | 0.5435 | 0.1594 | |
| SRP007169 | MAD2L1BP | 9587 | RNAseq | -0.0700 | 0.8619 | |
| SRP008496 | MAD2L1BP | 9587 | RNAseq | 0.0132 | 0.9575 | |
| SRP064894 | MAD2L1BP | 9587 | RNAseq | 0.4231 | 0.0619 | |
| SRP133303 | MAD2L1BP | 9587 | RNAseq | 0.4384 | 0.0207 | |
| SRP159526 | MAD2L1BP | 9587 | RNAseq | 0.0408 | 0.8186 | |
| SRP193095 | MAD2L1BP | 9587 | RNAseq | -0.0969 | 0.4783 | |
| SRP219564 | MAD2L1BP | 9587 | RNAseq | 0.0220 | 0.9272 | |
| TCGA | MAD2L1BP | 9587 | RNAseq | -0.0084 | 0.8902 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MAD2L1BP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAD2L1BP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAD2L1BP | 9587 | 7 | 0 | 23 | |
| GSE20123 | MAD2L1BP | 9587 | 7 | 0 | 23 | |
| GSE43470 | MAD2L1BP | 9587 | 6 | 0 | 37 | |
| GSE46452 | MAD2L1BP | 9587 | 2 | 9 | 48 | |
| GSE47630 | MAD2L1BP | 9587 | 8 | 4 | 28 | |
| GSE54993 | MAD2L1BP | 9587 | 3 | 2 | 65 | |
| GSE54994 | MAD2L1BP | 9587 | 10 | 4 | 39 | |
| GSE60625 | MAD2L1BP | 9587 | 0 | 1 | 10 | |
| GSE74703 | MAD2L1BP | 9587 | 6 | 0 | 30 | |
| GSE74704 | MAD2L1BP | 9587 | 3 | 0 | 17 | |
| TCGA | MAD2L1BP | 9587 | 22 | 11 | 63 |
Total number of gains: 74; Total number of losses: 31; Total Number of normals: 383.
Somatic mutations of MAD2L1BP:
Generating mutation plots.
Highly correlated genes for MAD2L1BP:
Showing top 20/1011 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAD2L1BP | KTI12 | 0.756288 | 3 | 0 | 3 |
| MAD2L1BP | TMEM167A | 0.729162 | 3 | 0 | 3 |
| MAD2L1BP | IER3IP1 | 0.726667 | 3 | 0 | 3 |
| MAD2L1BP | PPIL1 | 0.726334 | 8 | 0 | 8 |
| MAD2L1BP | HHEX | 0.722786 | 3 | 0 | 3 |
| MAD2L1BP | MRPL14 | 0.711878 | 8 | 0 | 6 |
| MAD2L1BP | RRP36 | 0.699844 | 7 | 0 | 6 |
| MAD2L1BP | NUP50 | 0.696639 | 5 | 0 | 5 |
| MAD2L1BP | SLC35B2 | 0.696089 | 4 | 0 | 4 |
| MAD2L1BP | RECQL | 0.68847 | 4 | 0 | 4 |
| MAD2L1BP | SNX20 | 0.680631 | 3 | 0 | 3 |
| MAD2L1BP | TCTN1 | 0.678921 | 3 | 0 | 3 |
| MAD2L1BP | MAD2L2 | 0.676035 | 5 | 0 | 4 |
| MAD2L1BP | TXNDC12 | 0.674721 | 6 | 0 | 6 |
| MAD2L1BP | DNASE2 | 0.670813 | 5 | 0 | 5 |
| MAD2L1BP | PSMG3 | 0.669514 | 4 | 0 | 4 |
| MAD2L1BP | NUS1 | 0.668495 | 3 | 0 | 3 |
| MAD2L1BP | SPATA13 | 0.667676 | 3 | 0 | 3 |
| MAD2L1BP | MRPL37 | 0.665124 | 5 | 0 | 4 |
| MAD2L1BP | MEA1 | 0.66404 | 10 | 0 | 9 |
For details and further investigation, click here
