| Full name: zinc finger HIT-type containing 6 | Alias Symbol: FLJ20729|NY-BR-75|BCD1 | ||
| Type: protein-coding gene | Cytoband: 1p22.3 | ||
| Entrez ID: 54680 | HGNC ID: HGNC:26089 | Ensembl Gene: ENSG00000117174 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZNHIT6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNHIT6 | 54680 | 218932_at | -0.0856 | 0.8118 | |
| GSE20347 | ZNHIT6 | 54680 | 218932_at | -0.4892 | 0.0279 | |
| GSE23400 | ZNHIT6 | 54680 | 218932_at | -0.0281 | 0.7915 | |
| GSE26886 | ZNHIT6 | 54680 | 218932_at | -0.4686 | 0.0183 | |
| GSE29001 | ZNHIT6 | 54680 | 218932_at | -0.1843 | 0.5286 | |
| GSE38129 | ZNHIT6 | 54680 | 218932_at | -0.2405 | 0.1237 | |
| GSE45670 | ZNHIT6 | 54680 | 218932_at | -0.3522 | 0.0029 | |
| GSE53622 | ZNHIT6 | 54680 | 92716 | -0.2078 | 0.0010 | |
| GSE53624 | ZNHIT6 | 54680 | 92716 | -0.1204 | 0.2361 | |
| GSE63941 | ZNHIT6 | 54680 | 218932_at | -0.4007 | 0.5488 | |
| GSE77861 | ZNHIT6 | 54680 | 218932_at | -0.5279 | 0.0773 | |
| GSE97050 | ZNHIT6 | 54680 | A_24_P113686 | 0.0444 | 0.8881 | |
| SRP007169 | ZNHIT6 | 54680 | RNAseq | 0.4352 | 0.3591 | |
| SRP008496 | ZNHIT6 | 54680 | RNAseq | 0.7473 | 0.0501 | |
| SRP064894 | ZNHIT6 | 54680 | RNAseq | -0.1609 | 0.3305 | |
| SRP133303 | ZNHIT6 | 54680 | RNAseq | -0.1071 | 0.4420 | |
| SRP159526 | ZNHIT6 | 54680 | RNAseq | -0.6214 | 0.0108 | |
| SRP193095 | ZNHIT6 | 54680 | RNAseq | -0.3137 | 0.0022 | |
| SRP219564 | ZNHIT6 | 54680 | RNAseq | -0.1636 | 0.6820 | |
| TCGA | ZNHIT6 | 54680 | RNAseq | 0.1213 | 0.0338 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNHIT6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNHIT6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNHIT6 | 54680 | 0 | 8 | 22 | |
| GSE20123 | ZNHIT6 | 54680 | 0 | 8 | 22 | |
| GSE43470 | ZNHIT6 | 54680 | 2 | 4 | 37 | |
| GSE46452 | ZNHIT6 | 54680 | 1 | 1 | 57 | |
| GSE47630 | ZNHIT6 | 54680 | 8 | 5 | 27 | |
| GSE54993 | ZNHIT6 | 54680 | 0 | 1 | 69 | |
| GSE54994 | ZNHIT6 | 54680 | 6 | 3 | 44 | |
| GSE60625 | ZNHIT6 | 54680 | 0 | 0 | 11 | |
| GSE74703 | ZNHIT6 | 54680 | 1 | 3 | 32 | |
| GSE74704 | ZNHIT6 | 54680 | 0 | 5 | 15 | |
| TCGA | ZNHIT6 | 54680 | 6 | 23 | 67 |
Total number of gains: 24; Total number of losses: 61; Total Number of normals: 403.
Somatic mutations of ZNHIT6:
Generating mutation plots.
Highly correlated genes for ZNHIT6:
Showing top 20/735 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNHIT6 | TCHP | 0.754723 | 3 | 0 | 3 |
| ZNHIT6 | TMTC3 | 0.752063 | 3 | 0 | 3 |
| ZNHIT6 | PLCD3 | 0.751663 | 3 | 0 | 3 |
| ZNHIT6 | NANS | 0.74241 | 3 | 0 | 3 |
| ZNHIT6 | MACC1 | 0.716124 | 3 | 0 | 3 |
| ZNHIT6 | CCNYL1 | 0.71221 | 4 | 0 | 4 |
| ZNHIT6 | PRDX3 | 0.710488 | 3 | 0 | 3 |
| ZNHIT6 | PRPF38A | 0.703011 | 4 | 0 | 3 |
| ZNHIT6 | ATF1 | 0.701562 | 4 | 0 | 3 |
| ZNHIT6 | BACE2 | 0.699365 | 3 | 0 | 3 |
| ZNHIT6 | GRHPR | 0.694987 | 3 | 0 | 3 |
| ZNHIT6 | RWDD2B | 0.694748 | 4 | 0 | 3 |
| ZNHIT6 | CRK | 0.693231 | 5 | 0 | 5 |
| ZNHIT6 | RECQL | 0.689771 | 3 | 0 | 3 |
| ZNHIT6 | RPP38 | 0.688146 | 3 | 0 | 3 |
| ZNHIT6 | SRP68 | 0.686931 | 4 | 0 | 3 |
| ZNHIT6 | ALDH1A3 | 0.686841 | 3 | 0 | 3 |
| ZNHIT6 | ZNF71 | 0.684699 | 3 | 0 | 3 |
| ZNHIT6 | SRFBP1 | 0.681955 | 4 | 0 | 4 |
| ZNHIT6 | RNFT1 | 0.681744 | 3 | 0 | 3 |
For details and further investigation, click here
