| Full name: replication factor C subunit 5 | Alias Symbol: RFC36 | ||
| Type: protein-coding gene | Cytoband: 12q24.23 | ||
| Entrez ID: 5985 | HGNC ID: HGNC:9973 | Ensembl Gene: ENSG00000111445 | OMIM ID: 600407 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RFC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RFC5 | 5985 | 213734_at | 0.0073 | 0.9956 | |
| GSE20347 | RFC5 | 5985 | 213734_at | -0.7153 | 0.0001 | |
| GSE23400 | RFC5 | 5985 | 213734_at | -0.1148 | 0.4188 | |
| GSE26886 | RFC5 | 5985 | 213734_at | -0.1986 | 0.6307 | |
| GSE29001 | RFC5 | 5985 | 203209_at | 1.1247 | 0.0052 | |
| GSE38129 | RFC5 | 5985 | 213734_at | -0.2431 | 0.2679 | |
| GSE45670 | RFC5 | 5985 | 213734_at | -0.1847 | 0.1466 | |
| GSE53622 | RFC5 | 5985 | 108876 | 0.7427 | 0.0000 | |
| GSE53624 | RFC5 | 5985 | 108876 | 1.0889 | 0.0000 | |
| GSE63941 | RFC5 | 5985 | 213734_at | 0.3172 | 0.3768 | |
| GSE77861 | RFC5 | 5985 | 203209_at | 0.9893 | 0.0026 | |
| GSE97050 | RFC5 | 5985 | A_23_P95302 | 0.2514 | 0.3631 | |
| SRP007169 | RFC5 | 5985 | RNAseq | 3.0934 | 0.0000 | |
| SRP008496 | RFC5 | 5985 | RNAseq | 2.3337 | 0.0000 | |
| SRP064894 | RFC5 | 5985 | RNAseq | 0.6676 | 0.0030 | |
| SRP133303 | RFC5 | 5985 | RNAseq | 0.6918 | 0.0012 | |
| SRP159526 | RFC5 | 5985 | RNAseq | 1.2254 | 0.0000 | |
| SRP193095 | RFC5 | 5985 | RNAseq | 0.6376 | 0.0000 | |
| SRP219564 | RFC5 | 5985 | RNAseq | 0.4863 | 0.1861 | |
| TCGA | RFC5 | 5985 | RNAseq | 0.4486 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by RFC5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RFC5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RFC5 | 5985 | 6 | 2 | 22 | |
| GSE20123 | RFC5 | 5985 | 6 | 2 | 22 | |
| GSE43470 | RFC5 | 5985 | 2 | 0 | 41 | |
| GSE46452 | RFC5 | 5985 | 9 | 1 | 49 | |
| GSE47630 | RFC5 | 5985 | 9 | 3 | 28 | |
| GSE54993 | RFC5 | 5985 | 0 | 5 | 65 | |
| GSE54994 | RFC5 | 5985 | 6 | 6 | 41 | |
| GSE60625 | RFC5 | 5985 | 0 | 0 | 11 | |
| GSE74703 | RFC5 | 5985 | 2 | 0 | 34 | |
| GSE74704 | RFC5 | 5985 | 3 | 2 | 15 | |
| TCGA | RFC5 | 5985 | 21 | 10 | 65 |
Total number of gains: 64; Total number of losses: 31; Total Number of normals: 393.
Somatic mutations of RFC5:
Generating mutation plots.
Highly correlated genes for RFC5:
Showing top 20/259 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RFC5 | UBE2T | 0.774593 | 5 | 0 | 5 |
| RFC5 | SAPCD2 | 0.73727 | 3 | 0 | 3 |
| RFC5 | SIX4 | 0.731541 | 4 | 0 | 4 |
| RFC5 | LIN9 | 0.72795 | 4 | 0 | 4 |
| RFC5 | ZIC5 | 0.717168 | 3 | 0 | 3 |
| RFC5 | NOP56 | 0.711896 | 3 | 0 | 3 |
| RFC5 | MGME1 | 0.710562 | 3 | 0 | 3 |
| RFC5 | HAGLROS | 0.705987 | 3 | 0 | 3 |
| RFC5 | MED30 | 0.690071 | 5 | 0 | 5 |
| RFC5 | TMEM44 | 0.687382 | 3 | 0 | 3 |
| RFC5 | CCSAP | 0.682581 | 3 | 0 | 3 |
| RFC5 | NUF2 | 0.682439 | 6 | 0 | 5 |
| RFC5 | PTCD1 | 0.673258 | 3 | 0 | 3 |
| RFC5 | MRPL47 | 0.673207 | 5 | 0 | 4 |
| RFC5 | CBX2 | 0.67198 | 3 | 0 | 3 |
| RFC5 | FAM200A | 0.671539 | 4 | 0 | 4 |
| RFC5 | SKA3 | 0.671419 | 4 | 0 | 4 |
| RFC5 | ADO | 0.670034 | 4 | 0 | 4 |
| RFC5 | ZC3HC1 | 0.667343 | 4 | 0 | 4 |
| RFC5 | SCNM1 | 0.664322 | 3 | 0 | 3 |
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