| Full name: chromobox 2 | Alias Symbol: MGC10561 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 84733 | HGNC ID: HGNC:1552 | Ensembl Gene: ENSG00000173894 | OMIM ID: 602770 |
| Drug and gene relationship at DGIdb | |||
Expression of CBX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CBX2 | 84733 | 226473_at | 1.3397 | 0.2321 | |
| GSE20347 | CBX2 | 84733 | 215989_at | 0.0851 | 0.3527 | |
| GSE23400 | CBX2 | 84733 | 215989_at | -0.1197 | 0.0088 | |
| GSE26886 | CBX2 | 84733 | 226473_at | 1.8930 | 0.0000 | |
| GSE29001 | CBX2 | 84733 | 215989_at | 0.0111 | 0.9564 | |
| GSE38129 | CBX2 | 84733 | 215989_at | 0.0258 | 0.7516 | |
| GSE45670 | CBX2 | 84733 | 226473_at | 1.3510 | 0.0014 | |
| GSE53622 | CBX2 | 84733 | 68743 | 1.0144 | 0.0000 | |
| GSE53624 | CBX2 | 84733 | 68743 | 1.6645 | 0.0000 | |
| GSE63941 | CBX2 | 84733 | 226473_at | 1.7788 | 0.0220 | |
| GSE77861 | CBX2 | 84733 | 226473_at | 0.7668 | 0.0073 | |
| GSE97050 | CBX2 | 84733 | A_33_P3423954 | 0.2654 | 0.3438 | |
| SRP007169 | CBX2 | 84733 | RNAseq | 0.7147 | 0.1539 | |
| SRP008496 | CBX2 | 84733 | RNAseq | 1.1834 | 0.0015 | |
| SRP064894 | CBX2 | 84733 | RNAseq | 1.2616 | 0.0002 | |
| SRP133303 | CBX2 | 84733 | RNAseq | 1.5018 | 0.0002 | |
| SRP159526 | CBX2 | 84733 | RNAseq | 2.6754 | 0.0000 | |
| SRP219564 | CBX2 | 84733 | RNAseq | 1.5292 | 0.0143 | |
| TCGA | CBX2 | 84733 | RNAseq | 1.3398 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by CBX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CBX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CBX2 | 84733 | 4 | 3 | 23 | |
| GSE20123 | CBX2 | 84733 | 4 | 3 | 23 | |
| GSE43470 | CBX2 | 84733 | 3 | 5 | 35 | |
| GSE46452 | CBX2 | 84733 | 34 | 0 | 25 | |
| GSE47630 | CBX2 | 84733 | 9 | 1 | 30 | |
| GSE54993 | CBX2 | 84733 | 2 | 5 | 63 | |
| GSE54994 | CBX2 | 84733 | 10 | 5 | 38 | |
| GSE60625 | CBX2 | 84733 | 6 | 0 | 5 | |
| GSE74703 | CBX2 | 84733 | 3 | 3 | 30 | |
| GSE74704 | CBX2 | 84733 | 4 | 3 | 13 | |
| TCGA | CBX2 | 84733 | 29 | 9 | 58 |
Total number of gains: 108; Total number of losses: 37; Total Number of normals: 343.
Somatic mutations of CBX2:
Generating mutation plots.
Highly correlated genes for CBX2:
Showing top 20/918 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CBX2 | DKK3 | 0.714736 | 3 | 0 | 3 |
| CBX2 | SAPCD2 | 0.701109 | 6 | 0 | 6 |
| CBX2 | TRIO | 0.687227 | 5 | 0 | 4 |
| CBX2 | TEAD4 | 0.684617 | 6 | 0 | 5 |
| CBX2 | WDR66 | 0.680376 | 5 | 0 | 5 |
| CBX2 | POP7 | 0.680104 | 5 | 0 | 5 |
| CBX2 | HAUS7 | 0.672521 | 3 | 0 | 3 |
| CBX2 | RFC5 | 0.67198 | 3 | 0 | 3 |
| CBX2 | COA6 | 0.669588 | 7 | 0 | 6 |
| CBX2 | CRELD2 | 0.664256 | 4 | 0 | 4 |
| CBX2 | SUPT6H | 0.66361 | 3 | 0 | 3 |
| CBX2 | AP2B1 | 0.663565 | 4 | 0 | 4 |
| CBX2 | SPP1 | 0.663134 | 7 | 0 | 7 |
| CBX2 | SDK1 | 0.659258 | 6 | 0 | 4 |
| CBX2 | ASH1L-AS1 | 0.656715 | 4 | 0 | 4 |
| CBX2 | GEMIN6 | 0.65523 | 5 | 0 | 4 |
| CBX2 | C4orf48 | 0.65388 | 7 | 0 | 5 |
| CBX2 | UHRF1 | 0.653052 | 5 | 0 | 5 |
| CBX2 | UBE2T | 0.652457 | 8 | 0 | 7 |
| CBX2 | DTYMK | 0.652159 | 5 | 0 | 5 |
For details and further investigation, click here
