FUBP3

 

Full name: far upstream element binding protein 3 Alias Symbol: 
Type: protein-coding gene Cytoband: 9q34.11-q34.12
Entrez ID: 8939 HGNC ID: HGNC:4005 Ensembl Gene: ENSG00000107164 OMIM ID: 603536
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of FUBP3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FUBP3 8939 212824_at -0.1209 0.6710
GSE20347 FUBP3 8939 212824_at -0.0801 0.6656
GSE23400 FUBP3 8939 212824_at 0.3518 0.0000
GSE26886 FUBP3 8939 212824_at 0.1430 0.4387
GSE29001 FUBP3 8939 212824_at 0.3794 0.1592
GSE38129 FUBP3 8939 212824_at 0.0190 0.8773
GSE45670 FUBP3 8939 212824_at 0.1382 0.3158
GSE53622 FUBP3 8939 164661 0.3033 0.0000
GSE53624 FUBP3 8939 164661 0.2831 0.0000
GSE63941 FUBP3 8939 212824_at -0.1697 0.6403
GSE77861 FUBP3 8939 212824_at 0.1774 0.2883
GSE97050 FUBP3 8939 A_33_P3326099 -0.1069 0.7333
SRP007169 FUBP3 8939 RNAseq 1.3190 0.0026
SRP008496 FUBP3 8939 RNAseq 1.1184 0.0006
SRP064894 FUBP3 8939 RNAseq 0.0520 0.7955
SRP133303 FUBP3 8939 RNAseq 0.3572 0.0128
SRP159526 FUBP3 8939 RNAseq 0.2097 0.1498
SRP193095 FUBP3 8939 RNAseq 0.1981 0.0635
SRP219564 FUBP3 8939 RNAseq -0.2653 0.2531
TCGA FUBP3 8939 RNAseq 0.0410 0.3718

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by FUBP3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of FUBP3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FUBP3 8939 6 9 15
GSE20123 FUBP3 8939 6 9 15
GSE43470 FUBP3 8939 5 7 31
GSE46452 FUBP3 8939 6 13 40
GSE47630 FUBP3 8939 3 16 21
GSE54993 FUBP3 8939 3 3 64
GSE54994 FUBP3 8939 12 9 32
GSE60625 FUBP3 8939 0 0 11
GSE74703 FUBP3 8939 5 5 26
GSE74704 FUBP3 8939 3 7 10
TCGA FUBP3 8939 27 26 43

Total number of gains: 76; Total number of losses: 104; Total Number of normals: 308.  


 

Somatic mutations of FUBP3:

 

Generating mutation plots.

 

Highly correlated genes for FUBP3:

 

Showing top 20/445 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FUBP3AGPAT40.791187303
FUBP3TFAM0.717165303
FUBP3GNG100.704404
FUBP3RAD210.700697303
FUBP3MRPS350.691192303
FUBP3SRFBP10.684503404
FUBP3RLF0.683215303
FUBP3ASXL20.679786404
FUBP3CNOT40.675994403
FUBP3NFKB10.672038303
FUBP3PRRC10.66921303
FUBP3SMG80.667456404
FUBP3CHD10.653998403
FUBP3DHX330.653624404
FUBP3SET0.649056504
FUBP3TOR1B0.64793211010
FUBP3KDSR0.647884303
FUBP3MITD10.646523503
FUBP3PHF200.645727303
FUBP3ACER30.645435303

For details and further investigation, click here