| Full name: ring finger protein 24 | Alias Symbol: G1L | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 11237 | HGNC ID: HGNC:13779 | Ensembl Gene: ENSG00000101236 | OMIM ID: 612489 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RNF24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF24 | 11237 | 204669_s_at | 0.1648 | 0.8466 | |
| GSE20347 | RNF24 | 11237 | 204669_s_at | 0.0406 | 0.7910 | |
| GSE23400 | RNF24 | 11237 | 204669_s_at | 0.1284 | 0.0600 | |
| GSE26886 | RNF24 | 11237 | 204669_s_at | 0.0962 | 0.6254 | |
| GSE29001 | RNF24 | 11237 | 210706_s_at | -0.2750 | 0.1540 | |
| GSE38129 | RNF24 | 11237 | 204669_s_at | 0.3789 | 0.1273 | |
| GSE45670 | RNF24 | 11237 | 204669_s_at | 0.3380 | 0.0708 | |
| GSE53622 | RNF24 | 11237 | 18514 | 0.6676 | 0.0000 | |
| GSE53624 | RNF24 | 11237 | 18514 | 0.3858 | 0.0000 | |
| GSE63941 | RNF24 | 11237 | 226542_at | -2.3822 | 0.0010 | |
| GSE77861 | RNF24 | 11237 | 210706_s_at | -0.0771 | 0.6282 | |
| GSE97050 | RNF24 | 11237 | A_24_P333019 | 0.5277 | 0.2232 | |
| SRP007169 | RNF24 | 11237 | RNAseq | -0.5000 | 0.2886 | |
| SRP008496 | RNF24 | 11237 | RNAseq | -0.1232 | 0.6979 | |
| SRP064894 | RNF24 | 11237 | RNAseq | 0.1503 | 0.5263 | |
| SRP133303 | RNF24 | 11237 | RNAseq | 0.3684 | 0.0601 | |
| SRP159526 | RNF24 | 11237 | RNAseq | 1.3187 | 0.0012 | |
| SRP193095 | RNF24 | 11237 | RNAseq | 0.5179 | 0.0021 | |
| SRP219564 | RNF24 | 11237 | RNAseq | 0.1140 | 0.8048 | |
| TCGA | RNF24 | 11237 | RNAseq | 0.1775 | 0.0304 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by RNF24 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF24 | 11237 | 12 | 3 | 15 | |
| GSE20123 | RNF24 | 11237 | 13 | 3 | 14 | |
| GSE43470 | RNF24 | 11237 | 10 | 1 | 32 | |
| GSE46452 | RNF24 | 11237 | 26 | 1 | 32 | |
| GSE47630 | RNF24 | 11237 | 18 | 4 | 18 | |
| GSE54993 | RNF24 | 11237 | 2 | 14 | 54 | |
| GSE54994 | RNF24 | 11237 | 24 | 2 | 27 | |
| GSE60625 | RNF24 | 11237 | 0 | 0 | 11 | |
| GSE74703 | RNF24 | 11237 | 9 | 1 | 26 | |
| GSE74704 | RNF24 | 11237 | 8 | 1 | 11 | |
| TCGA | RNF24 | 11237 | 39 | 11 | 46 |
Total number of gains: 161; Total number of losses: 41; Total Number of normals: 286.
Somatic mutations of RNF24:
Generating mutation plots.
Highly correlated genes for RNF24:
Showing top 20/145 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF24 | IRAK2 | 0.806627 | 3 | 0 | 3 |
| RNF24 | SUSD1 | 0.745954 | 3 | 0 | 3 |
| RNF24 | AP1G1 | 0.727878 | 3 | 0 | 3 |
| RNF24 | CRLF3 | 0.725178 | 3 | 0 | 3 |
| RNF24 | DNAJC7 | 0.7195 | 4 | 0 | 4 |
| RNF24 | DPP4 | 0.712985 | 3 | 0 | 3 |
| RNF24 | HGF | 0.707836 | 3 | 0 | 3 |
| RNF24 | RAPGEF6 | 0.706868 | 3 | 0 | 3 |
| RNF24 | SPCS3 | 0.703481 | 3 | 0 | 3 |
| RNF24 | TTC39C | 0.698608 | 3 | 0 | 3 |
| RNF24 | NUDT19 | 0.696637 | 3 | 0 | 3 |
| RNF24 | RSPH9 | 0.694652 | 3 | 0 | 3 |
| RNF24 | QSOX1 | 0.694503 | 3 | 0 | 3 |
| RNF24 | RRM2B | 0.692088 | 3 | 0 | 3 |
| RNF24 | NES | 0.692015 | 3 | 0 | 3 |
| RNF24 | ARHGAP17 | 0.68894 | 5 | 0 | 4 |
| RNF24 | ZNF547 | 0.688102 | 3 | 0 | 3 |
| RNF24 | ZFR | 0.687388 | 3 | 0 | 3 |
| RNF24 | PPP4R1 | 0.685946 | 3 | 0 | 3 |
| RNF24 | ANKRD11 | 0.684617 | 3 | 0 | 3 |
For details and further investigation, click here
