| Full name: cyclin dependent kinase 2 associated protein 2 | Alias Symbol: DOC-1R|p14 | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 10263 | HGNC ID: HGNC:30833 | Ensembl Gene: ENSG00000167797 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CDK2AP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDK2AP2 | 10263 | 203252_at | 0.4241 | 0.3685 | |
| GSE20347 | CDK2AP2 | 10263 | 203252_at | 0.2962 | 0.1275 | |
| GSE23400 | CDK2AP2 | 10263 | 203252_at | 0.1569 | 0.0478 | |
| GSE26886 | CDK2AP2 | 10263 | 203252_at | 0.8968 | 0.0013 | |
| GSE29001 | CDK2AP2 | 10263 | 203252_at | 0.0321 | 0.9358 | |
| GSE38129 | CDK2AP2 | 10263 | 203252_at | 0.3015 | 0.0270 | |
| GSE45670 | CDK2AP2 | 10263 | 203252_at | 0.3773 | 0.0997 | |
| GSE53622 | CDK2AP2 | 10263 | 19118 | -0.0184 | 0.8424 | |
| GSE53624 | CDK2AP2 | 10263 | 17943 | 0.1316 | 0.0131 | |
| GSE63941 | CDK2AP2 | 10263 | 203252_at | 2.2910 | 0.0006 | |
| GSE77861 | CDK2AP2 | 10263 | 203252_at | 0.2367 | 0.4360 | |
| GSE97050 | CDK2AP2 | 10263 | A_33_P3329839 | 0.2327 | 0.5259 | |
| SRP007169 | CDK2AP2 | 10263 | RNAseq | -0.7535 | 0.0581 | |
| SRP008496 | CDK2AP2 | 10263 | RNAseq | -0.5845 | 0.0172 | |
| SRP064894 | CDK2AP2 | 10263 | RNAseq | 0.4610 | 0.1566 | |
| SRP133303 | CDK2AP2 | 10263 | RNAseq | 0.6037 | 0.0193 | |
| SRP159526 | CDK2AP2 | 10263 | RNAseq | -0.0512 | 0.8273 | |
| SRP193095 | CDK2AP2 | 10263 | RNAseq | 0.1732 | 0.2326 | |
| SRP219564 | CDK2AP2 | 10263 | RNAseq | 0.4969 | 0.2222 | |
| TCGA | CDK2AP2 | 10263 | RNAseq | 0.0876 | 0.2029 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CDK2AP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDK2AP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDK2AP2 | 10263 | 10 | 3 | 17 | |
| GSE20123 | CDK2AP2 | 10263 | 10 | 3 | 17 | |
| GSE43470 | CDK2AP2 | 10263 | 5 | 2 | 36 | |
| GSE46452 | CDK2AP2 | 10263 | 14 | 3 | 42 | |
| GSE47630 | CDK2AP2 | 10263 | 8 | 5 | 27 | |
| GSE54993 | CDK2AP2 | 10263 | 3 | 1 | 66 | |
| GSE54994 | CDK2AP2 | 10263 | 13 | 4 | 36 | |
| GSE60625 | CDK2AP2 | 10263 | 0 | 3 | 8 | |
| GSE74703 | CDK2AP2 | 10263 | 4 | 1 | 31 | |
| GSE74704 | CDK2AP2 | 10263 | 8 | 1 | 11 | |
| TCGA | CDK2AP2 | 10263 | 30 | 8 | 58 |
Total number of gains: 105; Total number of losses: 34; Total Number of normals: 349.
Somatic mutations of CDK2AP2:
Generating mutation plots.
Highly correlated genes for CDK2AP2:
Showing top 20/885 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDK2AP2 | STK11IP | 0.769171 | 3 | 0 | 3 |
| CDK2AP2 | TMEM41A | 0.765685 | 3 | 0 | 3 |
| CDK2AP2 | MRPL21 | 0.754858 | 4 | 0 | 4 |
| CDK2AP2 | CLK2 | 0.736886 | 3 | 0 | 3 |
| CDK2AP2 | PAICS | 0.72879 | 3 | 0 | 3 |
| CDK2AP2 | ZNF837 | 0.723681 | 3 | 0 | 3 |
| CDK2AP2 | KLHDC3 | 0.722379 | 4 | 0 | 4 |
| CDK2AP2 | ZC3HC1 | 0.718555 | 4 | 0 | 4 |
| CDK2AP2 | FAM193A | 0.718406 | 3 | 0 | 3 |
| CDK2AP2 | FTO | 0.71774 | 3 | 0 | 3 |
| CDK2AP2 | FAM161A | 0.708534 | 4 | 0 | 4 |
| CDK2AP2 | TADA1 | 0.708118 | 3 | 0 | 3 |
| CDK2AP2 | MARK1 | 0.702296 | 3 | 0 | 3 |
| CDK2AP2 | CREB5 | 0.70064 | 3 | 0 | 3 |
| CDK2AP2 | PROX1 | 0.698567 | 3 | 0 | 3 |
| CDK2AP2 | TMEM44 | 0.696854 | 3 | 0 | 3 |
| CDK2AP2 | SWT1 | 0.695705 | 3 | 0 | 3 |
| CDK2AP2 | TMEM216 | 0.694096 | 3 | 0 | 3 |
| CDK2AP2 | SOCS4 | 0.692637 | 3 | 0 | 3 |
| CDK2AP2 | RNF2 | 0.69179 | 3 | 0 | 3 |
For details and further investigation, click here
