| Full name: guanylate binding protein 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p22.2 | ||
| Entrez ID: 2633 | HGNC ID: HGNC:4182 | Ensembl Gene: ENSG00000117228 | OMIM ID: 600411 |
Expression of GBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GBP1 | 2633 | 231577_s_at | 1.1215 | 0.3128 | |
| GSE20347 | GBP1 | 2633 | 202269_x_at | 0.8451 | 0.0310 | |
| GSE23400 | GBP1 | 2633 | 202269_x_at | 1.0758 | 0.0000 | |
| GSE26886 | GBP1 | 2633 | 202270_at | 1.1823 | 0.0536 | |
| GSE29001 | GBP1 | 2633 | 202270_at | 1.1867 | 0.0160 | |
| GSE38129 | GBP1 | 2633 | 202269_x_at | 0.6549 | 0.0295 | |
| GSE45670 | GBP1 | 2633 | 231577_s_at | 1.4039 | 0.0117 | |
| GSE53622 | GBP1 | 2633 | 100330 | 1.3260 | 0.0000 | |
| GSE53624 | GBP1 | 2633 | 100330 | 1.2825 | 0.0000 | |
| GSE63941 | GBP1 | 2633 | 202270_at | -2.5661 | 0.0811 | |
| GSE77861 | GBP1 | 2633 | 202269_x_at | 0.3079 | 0.5009 | |
| GSE97050 | GBP1 | 2633 | A_23_P62890 | 0.9528 | 0.1616 | |
| SRP007169 | GBP1 | 2633 | RNAseq | 2.7790 | 0.0000 | |
| SRP008496 | GBP1 | 2633 | RNAseq | 2.6320 | 0.0000 | |
| SRP064894 | GBP1 | 2633 | RNAseq | 1.0722 | 0.0002 | |
| SRP133303 | GBP1 | 2633 | RNAseq | 1.6372 | 0.0000 | |
| SRP159526 | GBP1 | 2633 | RNAseq | 0.2778 | 0.6620 | |
| SRP193095 | GBP1 | 2633 | RNAseq | 1.3466 | 0.0000 | |
| TCGA | GBP1 | 2633 | RNAseq | 0.5492 | 0.0000 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by GBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GBP1 | 2633 | 0 | 8 | 22 | |
| GSE20123 | GBP1 | 2633 | 0 | 8 | 22 | |
| GSE43470 | GBP1 | 2633 | 2 | 4 | 37 | |
| GSE46452 | GBP1 | 2633 | 1 | 1 | 57 | |
| GSE47630 | GBP1 | 2633 | 8 | 5 | 27 | |
| GSE54993 | GBP1 | 2633 | 0 | 1 | 69 | |
| GSE54994 | GBP1 | 2633 | 6 | 2 | 45 | |
| GSE60625 | GBP1 | 2633 | 0 | 0 | 11 | |
| GSE74703 | GBP1 | 2633 | 1 | 3 | 32 | |
| GSE74704 | GBP1 | 2633 | 0 | 5 | 15 | |
| TCGA | GBP1 | 2633 | 6 | 23 | 67 |
Total number of gains: 24; Total number of losses: 60; Total Number of normals: 404.
Somatic mutations of GBP1:
Generating mutation plots.
Highly correlated genes for GBP1:
Showing top 20/698 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GBP1 | TAP1 | 0.79444 | 11 | 0 | 11 |
| GBP1 | STAT1 | 0.786514 | 12 | 0 | 12 |
| GBP1 | EPSTI1 | 0.782707 | 8 | 0 | 7 |
| GBP1 | DDX60L | 0.765612 | 6 | 0 | 6 |
| GBP1 | CXCL9 | 0.751523 | 12 | 0 | 12 |
| GBP1 | CXCL10 | 0.743252 | 13 | 0 | 12 |
| GBP1 | CXCL11 | 0.741046 | 12 | 0 | 11 |
| GBP1 | CD80 | 0.740867 | 3 | 0 | 3 |
| GBP1 | ZNFX1 | 0.733068 | 8 | 0 | 8 |
| GBP1 | RBM12B | 0.728739 | 3 | 0 | 3 |
| GBP1 | IFIH1 | 0.727898 | 10 | 0 | 9 |
| GBP1 | EXOC8 | 0.727457 | 3 | 0 | 3 |
| GBP1 | SP110 | 0.726897 | 11 | 0 | 10 |
| GBP1 | OTUD6B | 0.726866 | 3 | 0 | 3 |
| GBP1 | PARP9 | 0.716635 | 8 | 0 | 8 |
| GBP1 | GTF2H1 | 0.713054 | 3 | 0 | 3 |
| GBP1 | IFI44 | 0.710263 | 12 | 0 | 11 |
| GBP1 | USP41 | 0.708755 | 3 | 0 | 3 |
| GBP1 | STAT2 | 0.705811 | 7 | 0 | 6 |
| GBP1 | LGALS8 | 0.705248 | 3 | 0 | 3 |
For details and further investigation, click here
