| Full name: PAT1 homolog 2 | Alias Symbol: Pat1a | ||
| Type: protein-coding gene | Cytoband: 15q21.1 | ||
| Entrez ID: 197135 | HGNC ID: HGNC:33630 | Ensembl Gene: ENSG00000229474 | OMIM ID: 614661 |
| Drug and gene relationship at DGIdb | |||
Expression of PATL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PATL2 | 197135 | 230753_at | 0.4754 | 0.3837 | |
| GSE26886 | PATL2 | 197135 | 230753_at | 0.1606 | 0.2444 | |
| GSE45670 | PATL2 | 197135 | 230753_at | 0.2152 | 0.1393 | |
| GSE53622 | PATL2 | 197135 | 51503 | 0.5428 | 0.0004 | |
| GSE53624 | PATL2 | 197135 | 51503 | 0.3821 | 0.0048 | |
| GSE63941 | PATL2 | 197135 | 230753_at | 0.0994 | 0.7056 | |
| GSE77861 | PATL2 | 197135 | 230753_at | -0.1129 | 0.4292 | |
| SRP133303 | PATL2 | 197135 | RNAseq | 0.0527 | 0.8673 | |
| SRP193095 | PATL2 | 197135 | RNAseq | 0.5879 | 0.0411 | |
| SRP219564 | PATL2 | 197135 | RNAseq | 1.0996 | 0.0434 | |
| TCGA | PATL2 | 197135 | RNAseq | 0.6741 | 0.1553 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PATL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PATL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PATL2 | 197135 | 3 | 4 | 23 | |
| GSE20123 | PATL2 | 197135 | 3 | 5 | 22 | |
| GSE43470 | PATL2 | 197135 | 4 | 4 | 35 | |
| GSE46452 | PATL2 | 197135 | 3 | 7 | 49 | |
| GSE47630 | PATL2 | 197135 | 8 | 10 | 22 | |
| GSE54993 | PATL2 | 197135 | 4 | 6 | 60 | |
| GSE54994 | PATL2 | 197135 | 5 | 7 | 41 | |
| GSE60625 | PATL2 | 197135 | 4 | 0 | 7 | |
| GSE74703 | PATL2 | 197135 | 4 | 3 | 29 | |
| GSE74704 | PATL2 | 197135 | 1 | 2 | 17 | |
| TCGA | PATL2 | 197135 | 12 | 16 | 68 |
Total number of gains: 51; Total number of losses: 64; Total Number of normals: 373.
Somatic mutations of PATL2:
Generating mutation plots.
Highly correlated genes for PATL2:
Showing top 20/30 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PATL2 | SIRPG | 0.697713 | 3 | 0 | 3 |
| PATL2 | RTN4RL1 | 0.679634 | 3 | 0 | 3 |
| PATL2 | GZMB | 0.621477 | 4 | 0 | 3 |
| PATL2 | IL2RB | 0.598513 | 4 | 0 | 3 |
| PATL2 | IL12RB1 | 0.59029 | 4 | 0 | 3 |
| PATL2 | ZBP1 | 0.577344 | 5 | 0 | 3 |
| PATL2 | PCED1B | 0.577222 | 5 | 0 | 4 |
| PATL2 | TFEC | 0.572258 | 4 | 0 | 3 |
| PATL2 | STRA6 | 0.561962 | 4 | 0 | 3 |
| PATL2 | HLA-F | 0.560334 | 7 | 0 | 5 |
| PATL2 | HCP5 | 0.556999 | 7 | 0 | 4 |
| PATL2 | LY86 | 0.555478 | 3 | 0 | 3 |
| PATL2 | IFNG | 0.555269 | 4 | 0 | 3 |
| PATL2 | CTLA4 | 0.554433 | 4 | 0 | 3 |
| PATL2 | CST7 | 0.552884 | 4 | 0 | 3 |
| PATL2 | CCL7 | 0.552546 | 4 | 0 | 3 |
| PATL2 | KLHL6 | 0.548052 | 3 | 0 | 3 |
| PATL2 | JAKMIP1 | 0.541165 | 5 | 0 | 4 |
| PATL2 | IRF1 | 0.539583 | 4 | 0 | 3 |
| PATL2 | PARVG | 0.529439 | 5 | 0 | 3 |
For details and further investigation, click here
