| Full name: opsin 3 | Alias Symbol: ERO|NMO-1|encephalopsin|PPP1R116 | ||
| Type: protein-coding gene | Cytoband: 1q43 | ||
| Entrez ID: 23596 | HGNC ID: HGNC:14007 | Ensembl Gene: ENSG00000054277 | OMIM ID: 606695 |
| Drug and gene relationship at DGIdb | |||
Expression of OPN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OPN3 | 23596 | 219032_x_at | 0.5363 | 0.5893 | |
| GSE20347 | OPN3 | 23596 | 219032_x_at | 0.0762 | 0.8167 | |
| GSE23400 | OPN3 | 23596 | 219032_x_at | 0.5669 | 0.0001 | |
| GSE26886 | OPN3 | 23596 | 219032_x_at | 0.3670 | 0.3219 | |
| GSE29001 | OPN3 | 23596 | 219032_x_at | 0.1750 | 0.6799 | |
| GSE38129 | OPN3 | 23596 | 219032_x_at | 0.5868 | 0.0140 | |
| GSE45670 | OPN3 | 23596 | 219032_x_at | 0.1443 | 0.5392 | |
| GSE63941 | OPN3 | 23596 | 219032_x_at | 0.4591 | 0.5963 | |
| GSE77861 | OPN3 | 23596 | 219032_x_at | 0.1064 | 0.8651 | |
| GSE97050 | OPN3 | 23596 | A_23_P74391 | 0.6783 | 0.1714 | |
| SRP007169 | OPN3 | 23596 | RNAseq | -0.0531 | 0.9216 | |
| SRP008496 | OPN3 | 23596 | RNAseq | 0.2402 | 0.5353 | |
| SRP064894 | OPN3 | 23596 | RNAseq | 0.5187 | 0.0241 | |
| SRP133303 | OPN3 | 23596 | RNAseq | 0.8228 | 0.0092 | |
| SRP159526 | OPN3 | 23596 | RNAseq | -0.1557 | 0.7200 | |
| SRP193095 | OPN3 | 23596 | RNAseq | 0.1486 | 0.4265 | |
| SRP219564 | OPN3 | 23596 | RNAseq | 1.1938 | 0.1167 | |
| TCGA | OPN3 | 23596 | RNAseq | 0.2237 | 0.0208 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OPN3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of OPN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OPN3 | 23596 | 7 | 1 | 22 | |
| GSE20123 | OPN3 | 23596 | 7 | 1 | 22 | |
| GSE43470 | OPN3 | 23596 | 6 | 1 | 36 | |
| GSE46452 | OPN3 | 23596 | 4 | 2 | 53 | |
| GSE47630 | OPN3 | 23596 | 15 | 0 | 25 | |
| GSE54993 | OPN3 | 23596 | 0 | 6 | 64 | |
| GSE54994 | OPN3 | 23596 | 18 | 0 | 35 | |
| GSE60625 | OPN3 | 23596 | 0 | 0 | 11 | |
| GSE74703 | OPN3 | 23596 | 6 | 1 | 29 | |
| GSE74704 | OPN3 | 23596 | 2 | 0 | 18 | |
| TCGA | OPN3 | 23596 | 42 | 4 | 50 |
Total number of gains: 107; Total number of losses: 16; Total Number of normals: 365.
Somatic mutations of OPN3:
Generating mutation plots.
Highly correlated genes for OPN3:
Showing top 20/61 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OPN3 | TANK | 0.765491 | 4 | 0 | 4 |
| OPN3 | NRG4 | 0.708744 | 3 | 0 | 3 |
| OPN3 | RTN4RL1 | 0.704585 | 4 | 0 | 4 |
| OPN3 | EML6 | 0.703256 | 3 | 0 | 3 |
| OPN3 | CPNE9 | 0.685041 | 3 | 0 | 3 |
| OPN3 | SIRPA | 0.666519 | 3 | 0 | 3 |
| OPN3 | ARHGAP22 | 0.665038 | 3 | 0 | 3 |
| OPN3 | HOXA11 | 0.664177 | 3 | 0 | 3 |
| OPN3 | WDR53 | 0.662763 | 3 | 0 | 3 |
| OPN3 | ASF1B | 0.648095 | 3 | 0 | 3 |
| OPN3 | ELMO3 | 0.640984 | 5 | 0 | 3 |
| OPN3 | TUBAL3 | 0.638838 | 3 | 0 | 3 |
| OPN3 | APCDD1 | 0.634138 | 3 | 0 | 3 |
| OPN3 | SIPA1L1 | 0.63073 | 3 | 0 | 3 |
| OPN3 | FLAD1 | 0.627473 | 4 | 0 | 3 |
| OPN3 | MYO10 | 0.618527 | 5 | 0 | 3 |
| OPN3 | LFNG | 0.617587 | 4 | 0 | 3 |
| OPN3 | POLR3G | 0.614593 | 6 | 0 | 3 |
| OPN3 | SLC39A4 | 0.600661 | 3 | 0 | 3 |
| OPN3 | IL31RA | 0.593435 | 3 | 0 | 3 |
For details and further investigation, click here
