| Full name: S100 calcium binding protein A6 | Alias Symbol: 2A9|PRA|CABP | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 6277 | HGNC ID: HGNC:10496 | Ensembl Gene: ENSG00000197956 | OMIM ID: 114110 |
| Drug and gene relationship at DGIdb | |||
Expression of S100A6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | S100A6 | 6277 | 217728_at | -0.1601 | 0.8634 | |
| GSE20347 | S100A6 | 6277 | 217728_at | -0.2394 | 0.1764 | |
| GSE23400 | S100A6 | 6277 | 217728_at | -0.1941 | 0.0584 | |
| GSE26886 | S100A6 | 6277 | 217728_at | 0.6046 | 0.0085 | |
| GSE29001 | S100A6 | 6277 | 217728_at | -0.8219 | 0.0388 | |
| GSE38129 | S100A6 | 6277 | 217728_at | -0.1742 | 0.3216 | |
| GSE45670 | S100A6 | 6277 | 217728_at | 0.2799 | 0.0501 | |
| GSE53622 | S100A6 | 6277 | 139741 | -0.5059 | 0.0000 | |
| GSE53624 | S100A6 | 6277 | 139741 | -0.1959 | 0.0080 | |
| GSE63941 | S100A6 | 6277 | 217728_at | -1.1314 | 0.0394 | |
| GSE77861 | S100A6 | 6277 | 217728_at | 0.5745 | 0.0493 | |
| GSE97050 | S100A6 | 6277 | A_23_P201711 | 0.1314 | 0.8067 | |
| SRP007169 | S100A6 | 6277 | RNAseq | -1.4510 | 0.0027 | |
| SRP008496 | S100A6 | 6277 | RNAseq | -1.1459 | 0.0008 | |
| SRP064894 | S100A6 | 6277 | RNAseq | -0.0104 | 0.9775 | |
| SRP133303 | S100A6 | 6277 | RNAseq | -0.0437 | 0.8578 | |
| SRP159526 | S100A6 | 6277 | RNAseq | 0.3113 | 0.4531 | |
| SRP193095 | S100A6 | 6277 | RNAseq | -0.2929 | 0.1554 | |
| SRP219564 | S100A6 | 6277 | RNAseq | -0.2401 | 0.4326 | |
| TCGA | S100A6 | 6277 | RNAseq | 0.1421 | 0.0501 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by S100A6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of S100A6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | S100A6 | 6277 | 14 | 0 | 16 | |
| GSE20123 | S100A6 | 6277 | 14 | 0 | 16 | |
| GSE43470 | S100A6 | 6277 | 6 | 2 | 35 | |
| GSE46452 | S100A6 | 6277 | 2 | 1 | 56 | |
| GSE47630 | S100A6 | 6277 | 15 | 0 | 25 | |
| GSE54993 | S100A6 | 6277 | 0 | 4 | 66 | |
| GSE54994 | S100A6 | 6277 | 16 | 0 | 37 | |
| GSE60625 | S100A6 | 6277 | 0 | 0 | 11 | |
| GSE74703 | S100A6 | 6277 | 6 | 1 | 29 | |
| GSE74704 | S100A6 | 6277 | 7 | 0 | 13 | |
| TCGA | S100A6 | 6277 | 39 | 1 | 56 |
Total number of gains: 119; Total number of losses: 9; Total Number of normals: 360.
Somatic mutations of S100A6:
Generating mutation plots.
Highly correlated genes for S100A6:
Showing top 20/222 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| S100A6 | RELA | 0.744684 | 4 | 0 | 4 |
| S100A6 | DNMBP | 0.724868 | 3 | 0 | 3 |
| S100A6 | CD99L2 | 0.716619 | 3 | 0 | 3 |
| S100A6 | ASAP2 | 0.703703 | 3 | 0 | 3 |
| S100A6 | ZDHHC9 | 0.703478 | 3 | 0 | 3 |
| S100A6 | PCDH18 | 0.69506 | 3 | 0 | 3 |
| S100A6 | NTPCR | 0.693591 | 3 | 0 | 3 |
| S100A6 | RPS27L | 0.693273 | 3 | 0 | 3 |
| S100A6 | EP400 | 0.683889 | 3 | 0 | 3 |
| S100A6 | IQGAP1 | 0.682863 | 3 | 0 | 3 |
| S100A6 | MMP15 | 0.681419 | 3 | 0 | 3 |
| S100A6 | NACC1 | 0.67734 | 4 | 0 | 3 |
| S100A6 | CPT1A | 0.676334 | 5 | 0 | 5 |
| S100A6 | ARMC6 | 0.668052 | 3 | 0 | 3 |
| S100A6 | VTI1B | 0.660976 | 3 | 0 | 3 |
| S100A6 | NDUFB10 | 0.659524 | 3 | 0 | 3 |
| S100A6 | YLPM1 | 0.653125 | 4 | 0 | 3 |
| S100A6 | ZNF746 | 0.652889 | 3 | 0 | 3 |
| S100A6 | ABCB6 | 0.652259 | 4 | 0 | 4 |
| S100A6 | CD109 | 0.650618 | 5 | 0 | 5 |
For details and further investigation, click here
