| Full name: NADH:ubiquinone oxidoreductase subunit B10 | Alias Symbol: PDSW | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 4716 | HGNC ID: HGNC:7696 | Ensembl Gene: ENSG00000140990 | OMIM ID: 603843 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NDUFB10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFB10 | 4716 | 223112_s_at | -0.0215 | 0.9851 | |
| GSE26886 | NDUFB10 | 4716 | 228301_x_at | 1.0961 | 0.0000 | |
| GSE45670 | NDUFB10 | 4716 | 223112_s_at | -0.0205 | 0.9144 | |
| GSE53622 | NDUFB10 | 4716 | 35502 | -0.1283 | 0.0319 | |
| GSE53624 | NDUFB10 | 4716 | 35502 | 0.2164 | 0.0001 | |
| GSE63941 | NDUFB10 | 4716 | 223112_s_at | 0.4171 | 0.2280 | |
| GSE77861 | NDUFB10 | 4716 | 223112_s_at | -0.0109 | 0.9807 | |
| GSE97050 | NDUFB10 | 4716 | A_23_P118105 | -0.1515 | 0.6812 | |
| SRP007169 | NDUFB10 | 4716 | RNAseq | -0.3216 | 0.3312 | |
| SRP008496 | NDUFB10 | 4716 | RNAseq | -0.3468 | 0.1620 | |
| SRP064894 | NDUFB10 | 4716 | RNAseq | 0.4250 | 0.2569 | |
| SRP133303 | NDUFB10 | 4716 | RNAseq | 0.3223 | 0.0137 | |
| SRP159526 | NDUFB10 | 4716 | RNAseq | 0.2317 | 0.4014 | |
| SRP193095 | NDUFB10 | 4716 | RNAseq | -0.0866 | 0.5088 | |
| SRP219564 | NDUFB10 | 4716 | RNAseq | 0.0881 | 0.8469 | |
| TCGA | NDUFB10 | 4716 | RNAseq | -0.0538 | 0.3263 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NDUFB10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFB10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFB10 | 4716 | 5 | 5 | 20 | |
| GSE20123 | NDUFB10 | 4716 | 5 | 4 | 21 | |
| GSE43470 | NDUFB10 | 4716 | 4 | 7 | 32 | |
| GSE46452 | NDUFB10 | 4716 | 38 | 1 | 20 | |
| GSE47630 | NDUFB10 | 4716 | 13 | 6 | 21 | |
| GSE54993 | NDUFB10 | 4716 | 3 | 5 | 62 | |
| GSE54994 | NDUFB10 | 4716 | 5 | 9 | 39 | |
| GSE60625 | NDUFB10 | 4716 | 4 | 0 | 7 | |
| GSE74703 | NDUFB10 | 4716 | 4 | 5 | 27 | |
| GSE74704 | NDUFB10 | 4716 | 3 | 2 | 15 | |
| TCGA | NDUFB10 | 4716 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of NDUFB10:
Generating mutation plots.
Highly correlated genes for NDUFB10:
Showing top 20/87 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFB10 | ECI1 | 0.734108 | 5 | 0 | 5 |
| NDUFB10 | HEXIM2 | 0.666932 | 4 | 0 | 4 |
| NDUFB10 | S100A6 | 0.659524 | 3 | 0 | 3 |
| NDUFB10 | NEBL-AS1 | 0.658991 | 3 | 0 | 3 |
| NDUFB10 | ADSL | 0.644983 | 4 | 0 | 3 |
| NDUFB10 | PDE6D | 0.643296 | 3 | 0 | 3 |
| NDUFB10 | DEXI | 0.625814 | 5 | 0 | 4 |
| NDUFB10 | ZCRB1 | 0.620891 | 4 | 0 | 3 |
| NDUFB10 | PRPF8 | 0.620446 | 3 | 0 | 3 |
| NDUFB10 | HSPA12A | 0.618496 | 3 | 0 | 3 |
| NDUFB10 | SERGEF | 0.617937 | 3 | 0 | 3 |
| NDUFB10 | BAD | 0.617083 | 4 | 0 | 3 |
| NDUFB10 | MXRA7 | 0.612394 | 4 | 0 | 3 |
| NDUFB10 | CALML4 | 0.61044 | 3 | 0 | 3 |
| NDUFB10 | DCTPP1 | 0.60651 | 6 | 0 | 5 |
| NDUFB10 | FTO | 0.604355 | 4 | 0 | 3 |
| NDUFB10 | MPG | 0.602761 | 6 | 0 | 5 |
| NDUFB10 | CD2BP2 | 0.60063 | 4 | 0 | 3 |
| NDUFB10 | MRPL40 | 0.600201 | 4 | 0 | 3 |
| NDUFB10 | COG7 | 0.599878 | 4 | 0 | 3 |
For details and further investigation, click here
