| Full name: TOX high mobility group box family member 3 | Alias Symbol: CAGF9 | ||
| Type: protein-coding gene | Cytoband: 16q12.1 | ||
| Entrez ID: 27324 | HGNC ID: HGNC:11972 | Ensembl Gene: ENSG00000103460 | OMIM ID: 611416 |
| Drug and gene relationship at DGIdb | |||
Expression of TOX3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TOX3 | 27324 | 216623_x_at | -0.5806 | 0.7739 | |
| GSE20347 | TOX3 | 27324 | 216623_x_at | 0.0353 | 0.8117 | |
| GSE23400 | TOX3 | 27324 | 216623_x_at | -0.1601 | 0.0023 | |
| GSE26886 | TOX3 | 27324 | 230745_s_at | -0.0015 | 0.9947 | |
| GSE29001 | TOX3 | 27324 | 216623_x_at | 0.0074 | 0.9856 | |
| GSE38129 | TOX3 | 27324 | 216623_x_at | -0.3411 | 0.4418 | |
| GSE45670 | TOX3 | 27324 | 230745_s_at | 0.0231 | 0.8512 | |
| GSE53622 | TOX3 | 27324 | 84783 | -2.3159 | 0.0000 | |
| GSE53624 | TOX3 | 27324 | 84783 | -2.5888 | 0.0000 | |
| GSE63941 | TOX3 | 27324 | 230745_s_at | 0.1399 | 0.5299 | |
| GSE77861 | TOX3 | 27324 | 230745_s_at | -0.0091 | 0.9384 | |
| GSE97050 | TOX3 | 27324 | A_23_P54681 | -0.0130 | 0.9725 | |
| SRP133303 | TOX3 | 27324 | RNAseq | -0.6817 | 0.4529 | |
| TCGA | TOX3 | 27324 | RNAseq | -2.5935 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by TOX3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TOX3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TOX3 | 27324 | 3 | 0 | 27 | |
| GSE20123 | TOX3 | 27324 | 3 | 0 | 27 | |
| GSE43470 | TOX3 | 27324 | 2 | 7 | 34 | |
| GSE46452 | TOX3 | 27324 | 38 | 1 | 20 | |
| GSE47630 | TOX3 | 27324 | 11 | 7 | 22 | |
| GSE54993 | TOX3 | 27324 | 2 | 5 | 63 | |
| GSE54994 | TOX3 | 27324 | 6 | 11 | 36 | |
| GSE60625 | TOX3 | 27324 | 4 | 0 | 7 | |
| GSE74703 | TOX3 | 27324 | 2 | 4 | 30 | |
| GSE74704 | TOX3 | 27324 | 3 | 0 | 17 | |
| TCGA | TOX3 | 27324 | 26 | 11 | 59 |
Total number of gains: 100; Total number of losses: 46; Total Number of normals: 342.
Somatic mutations of TOX3:
Generating mutation plots.
Highly correlated genes for TOX3:
Showing top 20/147 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TOX3 | TSPAN8 | 0.733356 | 6 | 0 | 6 |
| TOX3 | PPP1R1B | 0.720247 | 5 | 0 | 4 |
| TOX3 | CP | 0.706948 | 3 | 0 | 3 |
| TOX3 | PUS7L | 0.704014 | 3 | 0 | 3 |
| TOX3 | TMC5 | 0.693495 | 5 | 0 | 5 |
| TOX3 | CHRM1 | 0.692907 | 3 | 0 | 3 |
| TOX3 | MLPH | 0.665751 | 7 | 0 | 7 |
| TOX3 | SLC44A4 | 0.663678 | 7 | 0 | 6 |
| TOX3 | ZNF518A | 0.658838 | 3 | 0 | 3 |
| TOX3 | LRRC26 | 0.655223 | 3 | 0 | 3 |
| TOX3 | CHST9 | 0.652288 | 4 | 0 | 3 |
| TOX3 | ENPP5 | 0.651603 | 4 | 0 | 4 |
| TOX3 | SCGB2A1 | 0.647782 | 4 | 0 | 3 |
| TOX3 | AGR3 | 0.64258 | 3 | 0 | 3 |
| TOX3 | RPS24 | 0.641368 | 3 | 0 | 3 |
| TOX3 | TFF3 | 0.638825 | 7 | 0 | 6 |
| TOX3 | TMEM150A | 0.636234 | 3 | 0 | 3 |
| TOX3 | TCN1 | 0.628107 | 4 | 0 | 4 |
| TOX3 | LONRF3 | 0.626527 | 3 | 0 | 3 |
| TOX3 | IRF2BP1 | 0.620075 | 4 | 0 | 4 |
For details and further investigation, click here
