| Full name: secretin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 6343 | HGNC ID: HGNC:10607 | Ensembl Gene: ENSG00000070031 | OMIM ID: 182099 |
| Drug and gene relationship at DGIdb | |||
Expression of SCT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCT | 6343 | 221198_at | -0.1454 | 0.6406 | |
| GSE20347 | SCT | 6343 | 221198_at | -0.1695 | 0.0328 | |
| GSE23400 | SCT | 6343 | 221198_at | -0.1231 | 0.0020 | |
| GSE26886 | SCT | 6343 | 221198_at | 0.2956 | 0.0990 | |
| GSE29001 | SCT | 6343 | 221198_at | -0.1186 | 0.1973 | |
| GSE38129 | SCT | 6343 | 221198_at | -0.0793 | 0.4366 | |
| GSE45670 | SCT | 6343 | 221198_at | -0.3448 | 0.0009 | |
| GSE53622 | SCT | 6343 | 123448 | 0.6016 | 0.0000 | |
| GSE53624 | SCT | 6343 | 123448 | 0.6439 | 0.0000 | |
| GSE63941 | SCT | 6343 | 221198_at | -0.0619 | 0.8083 | |
| GSE77861 | SCT | 6343 | 221198_at | -0.0907 | 0.5920 | |
| GSE97050 | SCT | 6343 | A_23_P104594 | -0.6542 | 0.3240 | |
| SRP133303 | SCT | 6343 | RNAseq | 0.0933 | 0.7904 | |
| SRP219564 | SCT | 6343 | RNAseq | 0.8238 | 0.0555 | |
| TCGA | SCT | 6343 | RNAseq | 1.3472 | 0.0435 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SCT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCT | 6343 | 1 | 11 | 18 | |
| GSE20123 | SCT | 6343 | 1 | 12 | 17 | |
| GSE43470 | SCT | 6343 | 1 | 10 | 32 | |
| GSE46452 | SCT | 6343 | 7 | 8 | 44 | |
| GSE47630 | SCT | 6343 | 4 | 12 | 24 | |
| GSE54993 | SCT | 6343 | 3 | 1 | 66 | |
| GSE54994 | SCT | 6343 | 1 | 12 | 40 | |
| GSE60625 | SCT | 6343 | 0 | 0 | 11 | |
| GSE74703 | SCT | 6343 | 1 | 8 | 27 | |
| GSE74704 | SCT | 6343 | 0 | 8 | 12 | |
| TCGA | SCT | 6343 | 8 | 38 | 50 |
Total number of gains: 27; Total number of losses: 120; Total Number of normals: 341.
Somatic mutations of SCT:
Generating mutation plots.
Highly correlated genes for SCT:
Showing top 20/247 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCT | FLT4 | 0.717186 | 4 | 0 | 4 |
| SCT | TSPAN16 | 0.701208 | 3 | 0 | 3 |
| SCT | CSF2 | 0.663044 | 3 | 0 | 3 |
| SCT | STARD7-AS1 | 0.658277 | 3 | 0 | 3 |
| SCT | POU2F2 | 0.643128 | 4 | 0 | 3 |
| SCT | SLC22A31 | 0.640379 | 3 | 0 | 3 |
| SCT | TNK2 | 0.632692 | 3 | 0 | 3 |
| SCT | TSPO2 | 0.621801 | 4 | 0 | 4 |
| SCT | RASL10B | 0.61967 | 3 | 0 | 3 |
| SCT | NR0B2 | 0.614684 | 3 | 0 | 3 |
| SCT | GFI1B | 0.61268 | 4 | 0 | 4 |
| SCT | BFSP2 | 0.608622 | 3 | 0 | 3 |
| SCT | SLC22A13 | 0.607729 | 6 | 0 | 4 |
| SCT | LMAN1L | 0.607406 | 3 | 0 | 3 |
| SCT | LIN37 | 0.607106 | 3 | 0 | 3 |
| SCT | TNP1 | 0.607082 | 5 | 0 | 4 |
| SCT | DOK3 | 0.60326 | 4 | 0 | 3 |
| SCT | KLK8 | 0.60324 | 4 | 0 | 3 |
| SCT | RDH8 | 0.600677 | 4 | 0 | 3 |
| SCT | COL20A1 | 0.600412 | 3 | 0 | 3 |
For details and further investigation, click here
