| Full name: secreted and transmembrane 1 | Alias Symbol: K12 | ||
| Type: protein-coding gene | Cytoband: 17q25 | ||
| Entrez ID: 6398 | HGNC ID: HGNC:10707 | Ensembl Gene: ENSG00000141574 | OMIM ID: 602602 |
| Drug and gene relationship at DGIdb | |||
Expression of SECTM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SECTM1 | 6398 | 213716_s_at | 0.3362 | 0.5692 | |
| GSE20347 | SECTM1 | 6398 | 213716_s_at | 0.1675 | 0.4207 | |
| GSE23400 | SECTM1 | 6398 | 213716_s_at | 0.0791 | 0.3252 | |
| GSE26886 | SECTM1 | 6398 | 213716_s_at | 0.3851 | 0.3139 | |
| GSE29001 | SECTM1 | 6398 | 213716_s_at | 0.3386 | 0.3668 | |
| GSE38129 | SECTM1 | 6398 | 213716_s_at | 0.0867 | 0.6471 | |
| GSE45670 | SECTM1 | 6398 | 213716_s_at | 0.6445 | 0.0110 | |
| GSE53622 | SECTM1 | 6398 | 8765 | 0.1144 | 0.5318 | |
| GSE53624 | SECTM1 | 6398 | 8765 | 0.6575 | 0.0000 | |
| GSE63941 | SECTM1 | 6398 | 213716_s_at | -0.5899 | 0.4931 | |
| GSE77861 | SECTM1 | 6398 | 213716_s_at | -0.1227 | 0.6573 | |
| GSE97050 | SECTM1 | 6398 | A_24_P48204 | 0.2912 | 0.3419 | |
| SRP007169 | SECTM1 | 6398 | RNAseq | -0.6207 | 0.2859 | |
| SRP008496 | SECTM1 | 6398 | RNAseq | -0.4947 | 0.3016 | |
| SRP064894 | SECTM1 | 6398 | RNAseq | 0.5061 | 0.2151 | |
| SRP133303 | SECTM1 | 6398 | RNAseq | 0.7982 | 0.0222 | |
| SRP159526 | SECTM1 | 6398 | RNAseq | 0.0489 | 0.9348 | |
| SRP193095 | SECTM1 | 6398 | RNAseq | -0.4686 | 0.2188 | |
| SRP219564 | SECTM1 | 6398 | RNAseq | 1.3831 | 0.0031 | |
| TCGA | SECTM1 | 6398 | RNAseq | -0.0630 | 0.6357 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SECTM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SECTM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SECTM1 | 6398 | 4 | 5 | 21 | |
| GSE20123 | SECTM1 | 6398 | 4 | 5 | 21 | |
| GSE43470 | SECTM1 | 6398 | 3 | 5 | 35 | |
| GSE46452 | SECTM1 | 6398 | 34 | 0 | 25 | |
| GSE47630 | SECTM1 | 6398 | 9 | 2 | 29 | |
| GSE54993 | SECTM1 | 6398 | 2 | 5 | 63 | |
| GSE54994 | SECTM1 | 6398 | 10 | 6 | 37 | |
| GSE60625 | SECTM1 | 6398 | 6 | 0 | 5 | |
| GSE74703 | SECTM1 | 6398 | 3 | 3 | 30 | |
| GSE74704 | SECTM1 | 6398 | 4 | 4 | 12 | |
| TCGA | SECTM1 | 6398 | 23 | 13 | 60 |
Total number of gains: 102; Total number of losses: 48; Total Number of normals: 338.
Somatic mutations of SECTM1:
Generating mutation plots.
Highly correlated genes for SECTM1:
Showing top 20/343 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SECTM1 | PPP5C | 0.753359 | 3 | 0 | 3 |
| SECTM1 | MADD | 0.742405 | 3 | 0 | 3 |
| SECTM1 | KCND3 | 0.711029 | 3 | 0 | 3 |
| SECTM1 | ZBTB33 | 0.703451 | 3 | 0 | 3 |
| SECTM1 | EEFSEC | 0.700536 | 3 | 0 | 3 |
| SECTM1 | POLR2A | 0.700019 | 3 | 0 | 3 |
| SECTM1 | SNX20 | 0.699249 | 4 | 0 | 3 |
| SECTM1 | CD180 | 0.698452 | 5 | 0 | 3 |
| SECTM1 | TP53I11 | 0.697979 | 3 | 0 | 3 |
| SECTM1 | RALGAPA2 | 0.697139 | 4 | 0 | 3 |
| SECTM1 | KLHL3 | 0.696937 | 3 | 0 | 3 |
| SECTM1 | ZNF324B | 0.693887 | 3 | 0 | 3 |
| SECTM1 | GPR160 | 0.693446 | 3 | 0 | 3 |
| SECTM1 | UHMK1 | 0.688807 | 3 | 0 | 3 |
| SECTM1 | GDF9 | 0.684061 | 3 | 0 | 3 |
| SECTM1 | HAVCR2 | 0.682611 | 4 | 0 | 3 |
| SECTM1 | P2RY8 | 0.680423 | 3 | 0 | 3 |
| SECTM1 | HGF | 0.678306 | 4 | 0 | 3 |
| SECTM1 | RGS18 | 0.676223 | 4 | 0 | 3 |
| SECTM1 | FAM89B | 0.674414 | 3 | 0 | 3 |
For details and further investigation, click here
