| Full name: serpin family B member 10 | Alias Symbol: bomapin | ||
| Type: protein-coding gene | Cytoband: 18q21.3 | ||
| Entrez ID: 5273 | HGNC ID: HGNC:8942 | Ensembl Gene: ENSG00000242550 | OMIM ID: 602058 |
| Drug and gene relationship at DGIdb | |||
Expression of SERPINB10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SERPINB10 | 5273 | 214539_at | 0.3051 | 0.6955 | |
| GSE20347 | SERPINB10 | 5273 | 214539_at | 0.0223 | 0.7971 | |
| GSE23400 | SERPINB10 | 5273 | 214539_at | -0.1291 | 0.0018 | |
| GSE26886 | SERPINB10 | 5273 | 214539_at | -0.0409 | 0.7710 | |
| GSE29001 | SERPINB10 | 5273 | 214539_at | -0.0633 | 0.6958 | |
| GSE38129 | SERPINB10 | 5273 | 214539_at | -0.0665 | 0.4650 | |
| GSE45670 | SERPINB10 | 5273 | 214539_at | 0.0614 | 0.6227 | |
| GSE53622 | SERPINB10 | 5273 | 129245 | -1.5118 | 0.0000 | |
| GSE53624 | SERPINB10 | 5273 | 129245 | -2.2598 | 0.0000 | |
| GSE63941 | SERPINB10 | 5273 | 214539_at | 0.5197 | 0.5985 | |
| GSE77861 | SERPINB10 | 5273 | 214539_at | 0.1874 | 0.2849 | |
| GSE97050 | SERPINB10 | 5273 | A_23_P313981 | -0.0442 | 0.9603 | |
| SRP064894 | SERPINB10 | 5273 | RNAseq | -1.3494 | 0.0000 | |
| SRP133303 | SERPINB10 | 5273 | RNAseq | -0.3293 | 0.0883 | |
| SRP159526 | SERPINB10 | 5273 | RNAseq | -1.8153 | 0.0035 | |
| SRP193095 | SERPINB10 | 5273 | RNAseq | -0.5258 | 0.0202 | |
| SRP219564 | SERPINB10 | 5273 | RNAseq | -0.4959 | 0.3544 | |
| TCGA | SERPINB10 | 5273 | RNAseq | 1.5830 | 0.0979 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SERPINB10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SERPINB10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SERPINB10 | 5273 | 1 | 9 | 20 | |
| GSE20123 | SERPINB10 | 5273 | 1 | 9 | 20 | |
| GSE43470 | SERPINB10 | 5273 | 0 | 7 | 36 | |
| GSE46452 | SERPINB10 | 5273 | 1 | 26 | 32 | |
| GSE47630 | SERPINB10 | 5273 | 5 | 21 | 14 | |
| GSE54993 | SERPINB10 | 5273 | 9 | 0 | 61 | |
| GSE54994 | SERPINB10 | 5273 | 1 | 18 | 34 | |
| GSE60625 | SERPINB10 | 5273 | 0 | 4 | 7 | |
| GSE74703 | SERPINB10 | 5273 | 0 | 7 | 29 | |
| GSE74704 | SERPINB10 | 5273 | 1 | 6 | 13 | |
| TCGA | SERPINB10 | 5273 | 10 | 45 | 41 |
Total number of gains: 29; Total number of losses: 152; Total Number of normals: 307.
Somatic mutations of SERPINB10:
Generating mutation plots.
Highly correlated genes for SERPINB10:
Showing top 20/193 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SERPINB10 | SENP1 | 0.753216 | 3 | 0 | 3 |
| SERPINB10 | INPP5B | 0.716326 | 3 | 0 | 3 |
| SERPINB10 | LRRC34 | 0.693786 | 3 | 0 | 3 |
| SERPINB10 | MCMBP | 0.67878 | 3 | 0 | 3 |
| SERPINB10 | IFIT5 | 0.674648 | 3 | 0 | 3 |
| SERPINB10 | VPS33A | 0.67253 | 3 | 0 | 3 |
| SERPINB10 | NDUFA9 | 0.663114 | 3 | 0 | 3 |
| SERPINB10 | OR1A1 | 0.660546 | 5 | 0 | 5 |
| SERPINB10 | KANSL2 | 0.648109 | 3 | 0 | 3 |
| SERPINB10 | GTF2H1 | 0.647574 | 3 | 0 | 3 |
| SERPINB10 | GYG2 | 0.644526 | 4 | 0 | 3 |
| SERPINB10 | RASIP1 | 0.64387 | 3 | 0 | 3 |
| SERPINB10 | SYT17 | 0.641424 | 3 | 0 | 3 |
| SERPINB10 | PTGER4 | 0.631054 | 4 | 0 | 3 |
| SERPINB10 | PACS1 | 0.629136 | 3 | 0 | 3 |
| SERPINB10 | MLF2 | 0.62809 | 3 | 0 | 3 |
| SERPINB10 | PTPRU | 0.627741 | 4 | 0 | 4 |
| SERPINB10 | ZNF384 | 0.62681 | 4 | 0 | 3 |
| SERPINB10 | RBM17 | 0.625036 | 3 | 0 | 3 |
| SERPINB10 | SEC22B | 0.620199 | 3 | 0 | 3 |
For details and further investigation, click here
