| Full name: serpin family F member 1 | Alias Symbol: EPC-1|PIG35 | ||
| Type: protein-coding gene | Cytoband: 17p13.3 | ||
| Entrez ID: 5176 | HGNC ID: HGNC:8824 | Ensembl Gene: ENSG00000132386 | OMIM ID: 172860 |
| Drug and gene relationship at DGIdb | |||
SERPINF1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04310 | Wnt signaling pathway |
Expression of SERPINF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SERPINF1 | 5176 | 202283_at | -0.5894 | 0.3810 | |
| GSE20347 | SERPINF1 | 5176 | 202283_at | 0.4926 | 0.0292 | |
| GSE23400 | SERPINF1 | 5176 | 202283_at | 0.3813 | 0.0120 | |
| GSE26886 | SERPINF1 | 5176 | 202283_at | 1.7171 | 0.0036 | |
| GSE29001 | SERPINF1 | 5176 | 202283_at | 0.1435 | 0.8120 | |
| GSE38129 | SERPINF1 | 5176 | 202283_at | 0.2000 | 0.6429 | |
| GSE45670 | SERPINF1 | 5176 | 202283_at | -1.3921 | 0.0004 | |
| GSE53622 | SERPINF1 | 5176 | 9492 | 0.5472 | 0.0001 | |
| GSE53624 | SERPINF1 | 5176 | 9492 | 0.4853 | 0.0000 | |
| GSE63941 | SERPINF1 | 5176 | 202283_at | -2.0234 | 0.2460 | |
| GSE77861 | SERPINF1 | 5176 | 202283_at | 1.0486 | 0.0879 | |
| GSE97050 | SERPINF1 | 5176 | A_23_P100660 | 0.5771 | 0.1585 | |
| SRP007169 | SERPINF1 | 5176 | RNAseq | 3.9275 | 0.0000 | |
| SRP008496 | SERPINF1 | 5176 | RNAseq | 3.0844 | 0.0000 | |
| SRP064894 | SERPINF1 | 5176 | RNAseq | 1.1645 | 0.0059 | |
| SRP133303 | SERPINF1 | 5176 | RNAseq | 0.5599 | 0.1501 | |
| SRP159526 | SERPINF1 | 5176 | RNAseq | -0.1247 | 0.6441 | |
| SRP193095 | SERPINF1 | 5176 | RNAseq | 1.0770 | 0.0000 | |
| SRP219564 | SERPINF1 | 5176 | RNAseq | 0.8944 | 0.1780 | |
| TCGA | SERPINF1 | 5176 | RNAseq | -0.1147 | 0.3062 |
Upregulated datasets: 5; Downregulated datasets: 1.
Survival by SERPINF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SERPINF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SERPINF1 | 5176 | 4 | 2 | 24 | |
| GSE20123 | SERPINF1 | 5176 | 4 | 3 | 23 | |
| GSE43470 | SERPINF1 | 5176 | 3 | 6 | 34 | |
| GSE46452 | SERPINF1 | 5176 | 34 | 1 | 24 | |
| GSE47630 | SERPINF1 | 5176 | 8 | 1 | 31 | |
| GSE54993 | SERPINF1 | 5176 | 9 | 3 | 58 | |
| GSE54994 | SERPINF1 | 5176 | 8 | 8 | 37 | |
| GSE60625 | SERPINF1 | 5176 | 4 | 0 | 7 | |
| GSE74703 | SERPINF1 | 5176 | 2 | 3 | 31 | |
| GSE74704 | SERPINF1 | 5176 | 2 | 1 | 17 | |
| TCGA | SERPINF1 | 5176 | 20 | 21 | 55 |
Total number of gains: 98; Total number of losses: 49; Total Number of normals: 341.
Somatic mutations of SERPINF1:
Generating mutation plots.
Highly correlated genes for SERPINF1:
Showing top 20/820 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SERPINF1 | GPC6 | 0.780595 | 5 | 0 | 5 |
| SERPINF1 | BICC1 | 0.734333 | 8 | 0 | 7 |
| SERPINF1 | TMEM178A | 0.688386 | 3 | 0 | 3 |
| SERPINF1 | COL6A2 | 0.68505 | 10 | 0 | 10 |
| SERPINF1 | C1R | 0.680671 | 10 | 0 | 8 |
| SERPINF1 | DAB2 | 0.680621 | 11 | 0 | 9 |
| SERPINF1 | ANXA6 | 0.680022 | 10 | 0 | 10 |
| SERPINF1 | EFHD1 | 0.676242 | 5 | 0 | 4 |
| SERPINF1 | PTGER3 | 0.675721 | 6 | 0 | 6 |
| SERPINF1 | SFRP2 | 0.67387 | 7 | 0 | 6 |
| SERPINF1 | OLFML2B | 0.672643 | 9 | 0 | 8 |
| SERPINF1 | C11orf96 | 0.671932 | 4 | 0 | 4 |
| SERPINF1 | TMEM176B | 0.668205 | 11 | 0 | 7 |
| SERPINF1 | GALNT10 | 0.667212 | 7 | 0 | 7 |
| SERPINF1 | A2M-AS1 | 0.66687 | 3 | 0 | 3 |
| SERPINF1 | OLFML3 | 0.665253 | 12 | 0 | 10 |
| SERPINF1 | EDNRB | 0.66485 | 5 | 0 | 4 |
| SERPINF1 | LRRC25 | 0.664476 | 3 | 0 | 3 |
| SERPINF1 | ARRB2 | 0.663463 | 3 | 0 | 3 |
| SERPINF1 | S1PR1 | 0.66338 | 5 | 0 | 4 |
For details and further investigation, click here
