| Full name: sideroflexin 1 | Alias Symbol: FLJ12876|SLC56A1 | ||
| Type: protein-coding gene | Cytoband: 5q35.2 | ||
| Entrez ID: 94081 | HGNC ID: HGNC:16085 | Ensembl Gene: ENSG00000164466 | OMIM ID: 615569 |
| Drug and gene relationship at DGIdb | |||
Expression of SFXN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SFXN1 | 94081 | 218392_x_at | 0.7634 | 0.0971 | |
| GSE20347 | SFXN1 | 94081 | 218392_x_at | 0.4789 | 0.0102 | |
| GSE23400 | SFXN1 | 94081 | 218392_x_at | 0.5744 | 0.0000 | |
| GSE26886 | SFXN1 | 94081 | 218392_x_at | 1.0278 | 0.0000 | |
| GSE29001 | SFXN1 | 94081 | 218392_x_at | 0.4019 | 0.0598 | |
| GSE38129 | SFXN1 | 94081 | 218392_x_at | 0.8334 | 0.0000 | |
| GSE45670 | SFXN1 | 94081 | 218392_x_at | 0.5339 | 0.0017 | |
| GSE53622 | SFXN1 | 94081 | 97918 | 0.5853 | 0.0004 | |
| GSE53624 | SFXN1 | 94081 | 97918 | 0.4409 | 0.0064 | |
| GSE63941 | SFXN1 | 94081 | 218392_x_at | 0.2167 | 0.6187 | |
| GSE77861 | SFXN1 | 94081 | 218392_x_at | 0.6021 | 0.0393 | |
| SRP007169 | SFXN1 | 94081 | RNAseq | 1.0074 | 0.0020 | |
| SRP008496 | SFXN1 | 94081 | RNAseq | 0.4163 | 0.2112 | |
| SRP064894 | SFXN1 | 94081 | RNAseq | 0.4084 | 0.0537 | |
| SRP133303 | SFXN1 | 94081 | RNAseq | 0.7261 | 0.0006 | |
| SRP159526 | SFXN1 | 94081 | RNAseq | 0.9427 | 0.0800 | |
| SRP193095 | SFXN1 | 94081 | RNAseq | 0.5255 | 0.0002 | |
| SRP219564 | SFXN1 | 94081 | RNAseq | 0.4075 | 0.3086 | |
| TCGA | SFXN1 | 94081 | RNAseq | 0.2637 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SFXN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SFXN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SFXN1 | 94081 | 2 | 12 | 16 | |
| GSE20123 | SFXN1 | 94081 | 2 | 12 | 16 | |
| GSE43470 | SFXN1 | 94081 | 1 | 10 | 32 | |
| GSE46452 | SFXN1 | 94081 | 0 | 27 | 32 | |
| GSE47630 | SFXN1 | 94081 | 0 | 20 | 20 | |
| GSE54993 | SFXN1 | 94081 | 10 | 2 | 58 | |
| GSE54994 | SFXN1 | 94081 | 2 | 17 | 34 | |
| GSE60625 | SFXN1 | 94081 | 1 | 0 | 10 | |
| GSE74703 | SFXN1 | 94081 | 1 | 7 | 28 | |
| GSE74704 | SFXN1 | 94081 | 1 | 6 | 13 | |
| TCGA | SFXN1 | 94081 | 7 | 35 | 54 |
Total number of gains: 27; Total number of losses: 148; Total Number of normals: 313.
Somatic mutations of SFXN1:
Generating mutation plots.
Highly correlated genes for SFXN1:
Showing top 20/792 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SFXN1 | C4orf48 | 0.674826 | 4 | 0 | 4 |
| SFXN1 | OGDHL | 0.672115 | 4 | 0 | 3 |
| SFXN1 | TBCE | 0.671966 | 7 | 0 | 7 |
| SFXN1 | TSPAN17 | 0.671932 | 5 | 0 | 5 |
| SFXN1 | AEN | 0.658047 | 4 | 0 | 4 |
| SFXN1 | REL | 0.657899 | 4 | 0 | 3 |
| SFXN1 | SLC36A1 | 0.656292 | 6 | 0 | 6 |
| SFXN1 | NEK2 | 0.65029 | 6 | 0 | 6 |
| SFXN1 | HPRT1 | 0.648382 | 8 | 0 | 7 |
| SFXN1 | CDK5RAP2 | 0.645282 | 4 | 0 | 4 |
| SFXN1 | WDR66 | 0.641893 | 5 | 0 | 4 |
| SFXN1 | FEN1 | 0.640911 | 8 | 0 | 8 |
| SFXN1 | SLC4A1AP | 0.636756 | 6 | 0 | 5 |
| SFXN1 | TYMP | 0.636568 | 4 | 0 | 3 |
| SFXN1 | ACVR1C | 0.636223 | 3 | 0 | 3 |
| SFXN1 | TET3 | 0.633308 | 6 | 0 | 5 |
| SFXN1 | KIF4A | 0.630773 | 9 | 0 | 8 |
| SFXN1 | LINC00467 | 0.63052 | 3 | 0 | 3 |
| SFXN1 | NMT1 | 0.628886 | 8 | 0 | 6 |
| SFXN1 | BUB1B | 0.628776 | 7 | 0 | 6 |
For details and further investigation, click here
